- Advancements in Transdermal Drug Delivery
- Dermatology and Skin Diseases
- Skin Protection and Aging
- Dermatological and COVID-19 studies
- Contact Dermatitis and Allergies
- Drug-Induced Adverse Reactions
- Chemotherapy-related skin toxicity
- Neonatal skin health care
Tokuda Hospital
2022-2024
Acibadem City Clinic
2022-2024
Skin microbiome and skin physiology are important indicators of the epidermal homeostasis status. Stress models can reveal pathological conditions modulating effects. Here we investigated cutaneous in relation to after mild tape stripping (TS) without treatment compared two cosmetic leave-on lotions (pH 5.5 vs. pH 9.3) 25 healthy volunteers.The was analyzed by 16S-rRNA-gene amplicon sequencing put following parameter: barrier function (TEWA-Meter TM300), stratum corneum hydration...
Instrumentation technology for transepidermal water loss measurements has not been substantially modified since its introduction by Nilsson in 1977. Recent progress sensor development allowed a new arrangement using matrix of 30 sensors. Raw measurement values are processed with spatial statistical analysis. We aimed to compare the new, multi-sensor probe (Tewameter TM Hex) established Tewameter 300 and gain reference data parameters energy vapor concentration on skin.Baseline repeated volar...
Abstract Introduction Stratum corneum (SC) is essential for skin barrier function, mitigating water loss and shielding against potentially harmful substances allergens. The SC's lipid matrix, arranged in a lamellar structure, integral to its protective role. Our study explores the restoration effects of multilamellar cream with an acidic pH compared basic placebo on physiology interaction microbiome after stress induction via tape stripping (TS). Materials Methods In this double‐blind study,...
Non-invasive measurement of the stratum corneum hydration (SCH) with capacitance-based instrumentation is established in dermatological and cosmetic studies. We wanted to test reliability non-invasive self-measurements for SCH performed under real-life conditions by volunteers a Bluetooth-based (wireless) probe Corneometer® (CM 825i) transmitting data via smartphone application central server. Probes smartphones communicated using Bluetooth Low Energy. Data from were securely transferred...