A5048005867- Glycosylation and Glycoproteins Research
- Nanoplatforms for cancer theranostics
- Molecular Communication and Nanonetworks
- SARS-CoV-2 and COVID-19 Research
- Monoclonal and Polyclonal Antibodies Research
- Bacteriophages and microbial interactions
King Mongkut's University of Technology Thonburi
2022-2024
The urgent need for an effective COVID-19 therapy has propelled the exploration of innovative strategies to combat fast-mutating SARS-CoV-2 virus. This study attempted develop nanobodies (Nbs) against Omicron variants by redirecting 1.29 neutralizing Nb, a receptor-binding domain (RBD)-specific Nb that can protect various other than Omicron, target subvariant BA.5, variant used development bivalent vaccine. Error-prone libraries were constructed. Following two rounds selection using...
Tuberculosis (TB) is an infectious disease that considered a major public health problem worldwide. The current diagnostic technology for TB detection not efficient. Interferon-γ inducible protein 10 (IP-10) highly investigated biomarker diagnosis. Nanobody (Nb) novel type of antibody fragment which can be produced in microorganisms at low cost and could used to replace mAb diagnostics. This study focused on selection nanobody specific IP-10. Phage display was the initial screening...