A5034464933- Pharmacological Effects of Natural Compounds
- Inflammasome and immune disorders
- Fashion and Cultural Textiles
- Gut microbiota and health
- Probiotics and Fermented Foods
- Signaling Pathways in Disease
- Helicobacter pylori-related gastroenterology studies
- Cancer-related gene regulation
- Diet, Metabolism, and Disease
- Wnt/β-catenin signaling in development and cancer
- Attention Deficit Hyperactivity Disorder
- Nanocluster Synthesis and Applications
- Liver Disease Diagnosis and Treatment
- Biochemical Analysis and Sensing Techniques
- Asthma and respiratory diseases
- Alcohol Consumption and Health Effects
- IL-33, ST2, and ILC Pathways
- Context-Aware Activity Recognition Systems
- Dermatology and Skin Diseases
- Nanoplatforms for cancer theranostics
- Lipid metabolism and disorders
- Digestive system and related health
- Color perception and design
- Plant-derived Lignans Synthesis and Bioactivity
- Clostridium difficile and Clostridium perfringens research
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2018-2024
Shanghai University of Traditional Chinese Medicine
2018-2024
Chongqing University
2021-2022
Chongqing Cancer Hospital
2021-2022
Nanning Normal University
2019
Hisense (China)
2016
Yangzhou University
2011
Yangzhou Polytechnic Institute
2007-2009
In this study, we used DSS to establish an IBD mouse model study the preventive effect of Lactobacillus plantarum ( L. ) ZS62 on in context oxidative stress and immune response. We assessed mitigating strain mice by examining length histopathological changes colon, determining serum antioxidant index levels inflammatory cytokines, as well mRNA protein expression relevant genes. The results showed that could inhibit colonic atrophy mice, reduce degree damage, downregulate MDA, MPO, IL‐1 β ,...
Lactobacillus plantarum ZS62 is a newly isolated strain from naturally fermented yogurt that might offer some beneficial effects in the setting of alcohol-induced subacute liver injury. The liver-protective effect L. was investigated by gavage feeding mice with this (1 × 109 CFU/kg BW) before alcohol administration daily for 7 days. We then compared hepatic morphology, function indexes, lipid levels, inflammation, oxidative stress and mRNA expression metabolism- inflammation-related genes...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause gastrointestinal symptoms in the patients, but role of gut microbiota SARS-CoV-2 remains unclear. Thus, this study, we aim to investigate whether affects composition and function microbiota. In demonstrated for first time that significant shifts microbiome were appeared both SARS-CoV-2-infected asymptomatic symptomatic cases. The relative abundance Candidatus_Saccharibacteria was significantly increased, whereas...
The epithelial-mesenchymal transition (EMT) pathway can mediate tumour migration, and the occurrence of EMT is closely related to Wnt/β-catenin signalling pathway. purpose this paper was study effect Lactobacillus fermentum ZS09 (L. ZS09) on in mouse with azoxymethane/dextran sulfate sodium salt (AOM/DSS) induced colon cancer potential underlying mechanism.In study, a model established through intraperitoneal injection 10 mg/kg azoxymethane (AOM) three cycles 2.5% dextran (DSS) drinking...
Background Attention deficit hyperactivity disorder (ADHD), a prevalent neurodevelopmental in children, can be effectively alleviated by the herbal preparation Long Mu Qing Xin Mixture (LMQXM), but its mechanism has not been fully elucidated. Objective To scrutinize potential pharmacological mechanisms which LMQXM improves behavior spontaneously hypertensive rats (SHR/NCrl). Methods The SHR/NCrl were randomly stratified into model (SHR) group, methylphenidate hydrochloride (MPH) and groups...
Asthma severely interferes with people's lives through coughing, wheezing and inflammation of the lungs. Herbacetin is a class natural compounds that inhibit development inflammation. However, whether inhibits asthma has not been definitively studied.
Mycoplasma pneumoniae (MP) is one of the main pathogens causing community acquired pneumonia (CAP) in children and adults. Previous pharmacological clinical studies have shown that Polydatin (PD) exerts anti-inflammatory action by conferring protective benefit MP pneumonia. However, mechanism underlying PD on infection remains unclear. It was found alleviated MP-induced injury inhibiting caspase-1/gasdermin D (GSDMD)-mediated epithelial pyroptosis. The results demonstrated inhibited...
Abnormal proliferation and migration of human airway smooth-muscle cells (hASMC) play crucial roles in child asthma. We investigated the effect Six-ingredient-Xiao-qing-long decoction (SXD) on transforming growth factor (TGF)-β1-stimulated hASMC. Cell viability TGF-β1-induced hASMC were determined by CCK-8 transwell assays. The expressions FK506 binding protein 51 (FKBP51), kinase B (AKT), p-AKT RT-qPCR western blotting. In addition, FKBP51 overexpression (oeFKBP51) knockdown (siFKBP51)...