A5102749634- Silk-based biomaterials and applications
- Electrospun Nanofibers in Biomedical Applications
- Magnetic and Electromagnetic Effects
- Microbial Metabolic Engineering and Bioproduction
- 3D Printing in Biomedical Research
- Phytochemistry and biological activity of medicinal plants
- Mine drainage and remediation techniques
- Protein Hydrolysis and Bioactive Peptides
- Antimicrobial Peptides and Activities
- Polymer Surface Interaction Studies
- Viral Infectious Diseases and Gene Expression in Insects
- Bone Tissue Engineering Materials
- Advanced Radiotherapy Techniques
- Parallel Computing and Optimization Techniques
- Tailings Management and Properties
- Geoscience and Mining Technology
- Microfluidic and Bio-sensing Technologies
- Gastric Cancer Management and Outcomes
- Spaceflight effects on biology
- Silkworms and Sericulture Research
- Cellular Mechanics and Interactions
- Ocular Diseases and Behçet’s Syndrome
- Protein purification and stability
- Otitis Media and Relapsing Polychondritis
- Polysaccharides and Plant Cell Walls
Yonsei University
1991-2025
Harvard University
2012-2025
Gordon Center for Medical Imaging
2025
Massachusetts General Hospital
2025
Kangwon National University
2009-2022
Korea Institute of Geoscience and Mineral Resources
2016
Dong-A University Hospital
2002-2013
Saarland University
2013
Dong-A University
1999-2011
National Cancer Center
2011
Abstract There is no way of predicting whether a patient with recurrent oral ulcerations (ROU) will develop Behçet's disease (BD). In the absence valid laboratory test to exclude BD, such result in diagnostic problem when they occur as sole and earliest manifestation disease. We assessed prognosis ROU by performing prospective evaluations 67 patients who had only history were registered at Disease Specialty Clinic Severance Hospital Yonsei University, Seoul, Korea. Thirty‐five (52.2%)...
The efficacy of silk peptide in treatment atopic dermatitis was examined a picryl chloride-induced model NC/Nga mice. Silk ameliorated the development by lowering serum IgE concentration. Treatment cultured spleen cells with reduced production enhancing IFN-γ and reducing level IL-4. functional peptides were identified as mixture GAGA sequences containing mass spectrometry vitro assay. Our findings indicate that exerts an effect on modulating Th1/Th2 balance.
ABSTRACT This report describes fabrication of a millimeter‐scale three‐dimensional (3D) multicellular structure with central cavity based on magnetic levitation 3T3 cells that had ingested Fe 3 O 4 ‐containing microcapsules. Magnetically levitated initially formed disc‐shaped cell cluster at the air‐medium interface and transformed into spheroid (up to 2.8 mm in diameter) after 10‐day incubation under magnet. Hematoxylin‐and‐eosin‐stained section revealed an eosinophilic shell enclosed...
Cellular uptake of a protein microsphere was investigated in vitro. Fibroin microspheres with an average diameter approximately 1 µm were prepared Fluorescein isothiocyanate–dextran for the fluorescent core. Tomography, performed using confocal laser scanning microscopy, confirmed into cytoplasmic area 3T3 cells. Flow cytometry showed that cellular proportional to co-incubation time and concentration. It also revealed fibroin internalised by cells at different rates depending on cell cycle...
Abstract An elaborate control of fibroin self‐assembly is critical in determining the size, structure, and release properties a microcapsule. This report describes preparation microspheres submicron range using an aqueous solution nanoemulsified decane with mixed detergent Tween 80 Span 80. Nanodispersed water droplets containing molecules were dried under vacuum to facilitate coalescence then transformed suspended particles 200–1200 nm diameter. The method was also applied encapsulate...
This study was carried out to investigate the in vitro and vivo moisturizing properties percutaneous absorption of PEG-impregnated Aloe vera gel. The PEG-i-Aloe gel obtained from dewatering impregnation by soaking (DIS) leaf slice. property sample evaluated moisture determination using gravimetric method desiccator under different RH% water sorption-desorption test on human skin. transdermal penetration characteristics investigated Franz diffusion cell method. had high retention ability...
Background: The capability for DNA double-strand breaks (DSBs) repair is crucial inherent radiosensitivity of tumor and normal cells. We have investigated the clinicopathologic significance gene expression in nasopharyngeal (NP) carcinoma. Materials Methods: A total 65 NP cancer patients who received radiotherapy were included. immunopositivity to Ku 70, DNA-PKcs, MRN, RAD50, XRCC4, LIG4 examined all tissues. Results: comprised 42 males 23 females, with a median age 56 years (range, 18-84)....
Swine respiratory diseases induce severe economic losses in the swine industry worldwide. Several methods have been developed and applied to control these diseases. However, there are still problems of disease industry. Recently, egg yolk antibodies found offer several advantages for animals humans. In a previous study (24), causative pathogens were developed. remained, especially terms reduced laying rates. Therefore, experimental vaccines reformulated with various bacterial antigens After...
To prevent the shrinkage of aloe vera slices during air drying, a method utilizing shrink-proof layer was developed. The sample configured whole leaf slices, where 1 side or both sides were covered with filter papers as layers. After drying by varying temperature and slice thickness, characteristics, well several quality factors dried analyzed. In simulation curves, modified Page model showed best fitness, representing diffusion-controlled mechanism. Nonetheless, there trace constant-rate...
Cellular uptake of microspheres may cause physiological stress and toxicity. In this report, we investigated the effect cellular fibroin on growth, cell cycle progression, morphology 3T3 cells. The were prepared by physical cross-linking molecules without any chemical modification. Fluorescent are comprised fluorescein isothiocyanate-dextran core shell. More than 90% cells determined to be fluorescence-positive following 24-h incubation with fluorescent (0.17 mg/mL). Microsphere localization...
Abstract The clinical features and histopathologic findings of a 54‐year‐old Korean male who had retained the sting apparatus bee for four months are described. showed ulcerative, erythematous plaques with irregular borders which resembled cutaneous neoplasms such as squamous cell carcinoma. Histopathologic included epidermal necrosis marked pseudoepitheliomatous hyperplasia. In dermis, stick‐shaped was demonstrated intense lymphohistiocytic eosinophilic infiltrations were noted.