A5100777924- ZnO doping and properties
- Coronary Interventions and Diagnostics
- Ga2O3 and related materials
- Gas Sensing Nanomaterials and Sensors
- Viral Infections and Immunology Research
- Cardiovascular Function and Risk Factors
- Viral gastroenteritis research and epidemiology
- Advanced biosensing and bioanalysis techniques
- Fatty Acid Research and Health
- Cardiac Imaging and Diagnostics
- Cytomegalovirus and herpesvirus research
- Acute Myocardial Infarction Research
- Consumer Perception and Purchasing Behavior
- Copper-based nanomaterials and applications
- RNA Interference and Gene Delivery
- Nanowire Synthesis and Applications
- Antiplatelet Therapy and Cardiovascular Diseases
- Venous Thromboembolism Diagnosis and Management
- Lipid metabolism and biosynthesis
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Cancer, Lipids, and Metabolism
- Spectroscopy Techniques in Biomedical and Chemical Research
- Blood groups and transfusion
- Diverse Approaches in Healthcare and Education Studies
Korea Institute of Science and Technology
2004-2024
Soonchunhyang University
2008-2024
Korea University
2000-2022
Institute for Basic Science
2022
Marymount University
2020
Beijing Institute of Technology
2020
Yokohama National University
2020
Toshiba (Japan)
2020
Pusan National University Yangsan Hospital
2018
Sejong General Hospital
2017
Cancer immunotherapy represents a revolutionary strategy, leveraging the patient's immune system to inhibit tumor growth and alleviate immunosuppressive effects of microenvironment (TME). The recent emergence checkpoint blockade (ICB) therapies, particularly following first approval cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) inhibitors like ipilimumab, has led significant in cancer immunotherapy. extensive explorations on diverse antibodies have broadened therapeutic scope for...
Drug-eluting stents significantly improved angiographic and clinical outcomes compared with bare metal in diabetic patients. However, a comparison of everolimus-eluting sirolimus-eluting patients has not been evaluated. Therefore we effectiveness diabetes mellitus.This prospective, multicenter, randomized study stent (n=149) (n=151) implantation The primary end point was noninferiority in-segment late loss at 8 months. Clinical events were also monitored for least 12 Everolimus-eluting...
Park, Seung-Jung; Duk-Woo; Kim, Young-Hak; Kang, Soo-Jin; Lee, Seung-Whan; Cheol Whan; Han, Ki-Hoon; Seong-Wook; Yun, Sung-Cheol; Sang-Gon; Rha, Seung-Woon; Seong, In-Whan; Jeong, Myung-Ho; Hur, Seung-Ho; Nae-Hee; Yoon, Junghan; Yang, Joo-Young; Bong-Ki; Choi, Young-Jin; Chung, Wook-Sung; Lim, Do-Sun; Cheong, Sang-Sig; Kee-Sik; Chae, Jei Keon; Nah, Deuk-Young; Jeon, Doo-Soo; Seung, Ki Bae; Jang, Jae-Sik; Hun Sik; Keun Author Information
The inflammatory disease periodontitis results in tooth loss and can even lead to diseases of the whole body if not treated. Gingival crevicular fluid (GCF) reflects condition gingiva contains proteins transuded from serum or cells at inflamed sites. In this study, we aimed discover potential protein biomarkers for GCF proteome using LC-MS/MS. We identified 305 healthy individuals patients collected a sterile gel loading tip by ESI-MS/MS coupled nano-LC. Among these proteins, about 45 were...
Abstract Previously, we explored the epidemic pattern and molecular characterization of enteroviruses isolated in Chungnam, Korea from 2005 to 2006. The present study extended these observations 2008 2009. In this study, showed similar seasonal prevalent summer fall age distribution previous investigation. most month was July: 42.9% 31.9% highest rate enterovirus-positive samples occurred children < 1-year-old-age. Enterovirus-positive were subjected sequence determination VP1 region,...
Hand-foot-and-mouth disease (HFMD) and herpangina are commonly prevalent illness in young children. They similarly characterized by lesions on the skin oral mucosa. Both diseases associated with various enterovirus serotypes. In this study, enteroviruses from patients these Korea 2009 were isolated analyzed. Demographic data for HFMD compared all isolates amplified VP1 region reverse transcription-polymerase chain reaction sequenced. Among isolates, agents coxsackievirus A16 A5 herpangina....
In vitro and in vivo osteogenesis of skin-derived mesenchymal stem cell–like cells (SDMSCs) with a demineralized bone (DMB) fibrin glue scaffold were compared. SDMSCs isolated from the ears adult miniature pigs evaluated for expression transcriptional factors (Oct-4, Sox-2, Nanog) MSC marker proteins (CD29, CD44, CD90, vimentin). The cocultured mixed DMB nonosteogenic medium 1, 2, 4 weeks. Osteonectin, osteocalcin, Runx2 expressed during culture period reached maximum at 2 weeks after...
Abstract Multivalent presentation of ligands often enhances receptor activation and downstream signaling. DNA origami offers precise nanoscale spacing ligands, a potentially useful feature for therapeutic nanoparticles. Here we introduce “square block” platform to explore the importance CpG oligonucleotides, which engage Toll-like receptors thereby act as danger signals dendritic cells. Through in vitro cell-culture studies vivo tumor-treatment models, demonstrate that square blocks induce...
Interactions of various ligands and receptors have been extensively investigated because they regulate a series signal transduction leading to functional cellular outcomes. The on cell membrane recognize their specific ligands, resulting in binding between receptors. Accumulating evidence reveals that the difference spatial characteristics as well types ligands. Thus, control multiple presented therapeutic nanoparticles is believed impact functions. Specifically, localized multivalent...
Diagnostic Hematology
Objective . Since oligodendrocyte progenitor cells (OPCs) are the target of neonatal hypoxic-ischemic encephalopathy (HIE), present study was aimed at investigating protective effects N -acetyl- L -cysteine (NAC), a well-known antioxidant and precursor glutathione, in OPCs as well rats. Methods In vitro study, NAC on KCN cytotoxicity F3.Olig2 were investigated via MTT assay apoptotic signal analysis. vivo administered to rats with HIE induced by hypoxia-ischemia surgery postnatal day 7,...
In this paper, we present experimental results describing enhanced readout of the vibratory response a doubly clamped zinc oxide (ZnO) nanowire employing purely electrical actuation and detection scheme. The measured suggests that piezoelectric semiconducting properties ZnO effectively enhance motional current for electromechanical transduction. For resonator with radius ~10 nm length ~1.91 µm, resonant frequency around 21.4 MHz is observed quality factor (Q) ~358 in vacuum. A comparison Q...
The case of an early retroperitoneal abdominal pregnancy implanted on inferior vena cava successfully resected through laparoscopic surgery is reported here. A 28-year-old woman presented with vaginal spotting and amenorrhrea for 7+5 weeks. Although a diagnosis right cornual ectopic by transvaginal ultrasound was made wedge resection the left uterine cornus performed, β-human chorionic gonadotropin level remained high. Abdominal ultrasonography computerized tomography abdomen demonstrated...
Background: Central nervous system (CNS) complications such as seizures and reduced consciousness are important in glufosinate may occur severe glyphosate poisoning. The aim of this study was to assess the possible role serum S100B protein a biochemical marker CNS associated with or poisoning.Methods: enrolled 40 patients (23 poisoning 17 poisoning). Altered seizure were observed during hospitalization. level measured fully automated modular analytic E170 using electrochemoluminometric...
Background: To evaluate the age-adjusted Framingham risk score (AFRS), flow-mediated dilation (FMD) and brachial-ankle pulse wave velocity (baPWV) for prediction of coronary heart disease (CHD) in patients with stable angina. Methods Results: In 138 consecutive angina, interrelationship predictive power CHD were compared between study parameters. total, 71 demonstrated after scheduled angiography. The AFRS showed significant correlation FMD (r=-0.43, P<0.01) baPWV (r=0.41, P<0.01). Based on...