A5100781072- Acute Myeloid Leukemia Research
- Venous Thromboembolism Diagnosis and Management
- Chronic Myeloid Leukemia Treatments
- Clinical Laboratory Practices and Quality Control
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood groups and transfusion
- Health and Medical Research Impacts
- Hematopoietic Stem Cell Transplantation
- Sarcoma Diagnosis and Treatment
- Immune Cell Function and Interaction
- Renal and Vascular Pathologies
- Atrial Fibrillation Management and Outcomes
- Inflammatory Biomarkers in Disease Prognosis
- Urologic and reproductive health conditions
- Meta-analysis and systematic reviews
- 3D Printing in Biomedical Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Innovations in Medical Education
- Diverse Approaches in Healthcare and Education Studies
- Hematological disorders and diagnostics
- Platelet Disorders and Treatments
- Wastewater Treatment and Nitrogen Removal
- Primary Care and Health Outcomes
- Teratomas and Epidermoid Cysts
- Barrier Structure and Function Studies
Soonchunhyang University
2016-2025
Mayo Clinic in Florida
2024
Hallym University Sacred Heart Hospital
2024
Samsung Medical Center
2006-2023
The Ohio State University
2023
St Mary's Hospital
2020
University of Victoria
2018
Soonchunhyang University Hospital
2018
Hanyang University
2014-2018
Asan Medical Center
2010-2017
Abstract Nutrient pollution and thermal stress constitute two of the main drivers global change in coastal oceans. While different studies have addressed physiological effects ecological consequences these stressors corals, role acquired modifications coral epigenome during acclimatory adaptive responses remains unknown. The present work aims to address that gap by monitoring types epigenetic mechanisms, namely histone DNA methylation, a 7‐week‐long experiment which staghorn fragments (...
The purpose of this article is to present the radiological findings peripheral primitive neuroectodermal tumors that arise in retroperitoneum.Peripheral (PNETs) arising retroperitoneum tend be large and aggressive. Although imaging appearance PNETs nonspecific, these should considered differential diagnosis when one encounters a retroperitoneal mass with aggressive features.
F-GP1 is a derivative of elarofiban with high affinity to activated platelet glycoprotein IIb/IIIa (GPIIb/IIIa) and favorable in vivo characteristics for thrombus imaging preclinical models. We aimed explore the detection rate thromboembolic foci
Abstract Objectives This study aimed to evaluate the performance of PBIA (UIMD, Seoul, Republic Korea), an automated digital morphology analyzer using deep learning, for white blood cell (WBC) classification in peripheral smears and compare it with widely used DI-60 (Sysmex, Kobe, Japan). Methods A total 461 slides were analyzed DI-60. For each instrument, pre-classification was evaluated on basis post-classification results verified by users. Pre- compared manual WBC differentials, ability...
Diagnostic Hematology
Embolization is a nonsurgical, minimally invasive procedure that deliberately blocks blood vessel. Although several embolic particles have been commercialized, their much wider applications hampered owing mainly to particle size variation and uncontrollable degradation kinetics. Herein we introduce microfluidic approach fabricate highly monodisperse gelatin microparticles (GMPs) with microshell structure. For this purpose, uniform emulsion precursors using technique consecutively cross-link...
High on-treatment platelet reactivity (HTPR) is the phenomenon wherein patients exhibit normal activity in laboratory testing despite adequate adherence to anti-platelet treatment. We investigated detection rates of Platelet Function Analyzer (PFA)-100 (Dade Behring AG, Düdingen, Switzerland) for drug-induced dysfunction and analyzed potential contributors HTPR with practical PFA-100 data over six years.We used from 6,957 who underwent after receiving aspirin, clopidogrel, or non-steroidal...
Microbially enhanced oil recovery involves the use of microorganisms to extract remaining in reservoirs. Here, we report fabrication microgel particles with immobilized Bacillus subtilis for application microbially recovery. Using B. isolated from oil-contaminated soils Myanmar, evaluated ability this microbe reduce interfacial tension at oil-water interface via production biosurfactant molecules, eventually yielding excellent emulsification across a broad range medium pH and ionic strength....
Aerobic granulation was characterized using three different wastewaters consisting of a sole organic substrate, ammonium and combination both substrates. The formation aerobic granules in each wastewater presented physical, chemical, morphological, microbial characteristics. faster larger loose occurred at the high concentration 1,000 mg COD/L; while compact small size (0.6 mm) could be developed when nitrification involved granulation. chemical changes biomass growth were mainly dominated...
Objective Various hematologic side effects of the Coronavirus Disease 2019 (COVID-19) vaccination has been reported, and most them are thought to be related autoimmune pathways. To best our knowledge, only few cases post-COVID-19 aplastic anemia (AA) have reported there is no Korean case COVID-19 vaccine-induced AA yet. We present a severe immune-mediated that developed after administration messenger ribonucleic acid (mRNA) gene-based spike protein vaccine against COVID-19, which responded...
Poor reporting quality in diagnostic accuracy studies hampers an adequate judgment of the validity study. The Standards for Reporting Diagnostic Accuracy Studies (STARD) statement was published to improve studies. This study aimed evaluate adherence Annals Laboratory Medicine (ALM) STARD 2015 and identify directions improvement these studies.Two independent authors assessed articles ALM between 2012-2018 compliance with 30 checklist items all eligible during this period. We included 66 A...
Background: The prothrombin time may be used to monitor the plasma concentration of rivaroxaban. However, there is variability in responsiveness rivaroxaban different thromboplastins. We aimed develop a rivaroxaban-monitoring method using reduce differences sensitivity among reagents.Methods: Rivaroxaban-spiked pooled normal at 0–1000 ng/ml was generate rivaroxaban-adjusted index (SI) values, and tested with three warfarin-adjusted international (ISI-warfarin), (SI-rivaroxaban), normalized...
Abstract Background The assessment of measurement uncertainty (MU) in clinical laboratories is essential to the reliable interpretation results laboratories. However, despite introduction various methods for expression measurement, MUs coagulation tests have not been extensively studied. aim this study was quantify MU assays according international guidelines and report an expected confidence quality assays. Methods We selected activated partial thromboplastin time, normalized ratio (INR),...
We prospectively evaluated prognostic value of lymphocyte subpopulations in peripheral blood allogeneic hematopoietic stem cell transplant (HSCT) recipients.113 HSCT (47 sibling matched, 37 unrelated 29 haploidentical)-performed patients diagnosed as AML (n = 66), ALL 28), and MDS 19) were enrolled. 14 quantified by flow cytometry PB at specific time-points after HSCT, their impacts analyzed.At 1, 2, 3 months post-HSCT, significant adverse impact on overall survival (OS) and/or event free...
Purpose: Sepsis is a critical condition in which nurses should detect clinical manifestations and provide early intervention to prevent unwanted serious conditions the patients. The initial occurrence management of sepsis take place general units, but there lack knowledge nurses. purpose this study was examine effects case-based education program compare with without smartphone applications. Methods: A quasi-experimental pre-test-post-test design control group used. We provided applications...
Background: We investigated the importance of lupus anticoagulant (LA) in patients with SARS-CoV-2. Methods: Medical records 41 SARS-CoV-2 infected were reviewed. Patients classified into two groups according to frequency positive LA test results: “LA (−)” and (+) ≥1” (LA at least once). Statistical analysis was performed determine association between presence change results disease course both hospital days (HD) after diagnosis (DD). Results: The prevalence 51.2%. Averagely, first result...
Summary Introduction This study investigates the benefits of using multiplex reverse transcriptase‐ PCR ( RT ‐ ) in addition to standard karyotyping during initial evaluation acute leukemia. Methods A total 1114 consecutive specimens from patients with leukemia were tested a commercial kit (HemaVision, DNA Diagnostic). NPM 1 and CEBPA mutations selectively myeloid AML negativity. Results In optimal cytogenetics, frequency recurrent translocations was 31.3%, cryptic detected 2.1% samples. The...
Newborn screening for congenital adrenal hyperplasia (CAH) has benefits with a high adoption rate worldwide. It also problems of false positives, which can cause stress to the patient's family economic losses and unnecessary visits newborns hospitals. Therefore, we investigated influence birth weight (BW), gestational age (GA), GA sampling time on 17-hydroxyprogesterone (17-OHP) concentration attempted establish 17-OHP cutoff values in preterm, low (LBW), sick newborns.Newborns (n=1,071)...
In gastric cancer (GC), MET and EGFR amplification have been identified in 2∼24% 27∼64% of patients, respectively. This study characterized 286 carcinogenesis-related gene alterations copy number variation (CNV) four human GC cell lines, analyzed difference the susceptibilities these cells to pelitinib, tepotinib, docetaxel. Using a next-generation sequencing panel, we evaluated CNV cells. We also assessed antitumor activity docetaxel lines xenograft model. The effects on viability (IC50),...
본 논의는 가능세계가 작동하는 방식을 살피기 위해, 진실에 관한 두 유형의 텍스트, 실제 경험을 기록하는 텍스트와 믿음을 진실로 수용하는 텍스트를 살폈다. 첫째 유형인 기록적 텍스트의 예로 생애담과 일기를 분석하였다. 일반적으로 이 텍스트들은 발신자가 자기 있는 그대로 기록하고, 발신자에 의해 의미화된 텍스트라고 여긴다. 그러나 발신자의 경험이 진실이 되려면 수신자의 지식에 유도되고 의미화되어야 한다. 둘째 유형으로는 종교적 믿음이나 추종적 담고 이들은 원천과 무관하게 믿음으로 재조직된(될 수있)다.수신자는 경험 진실이라는 위상을 확대하여 의미화할 수도, 허구적인 것으로 재생산할 수도 있다. 믿음 텍스트가 지닌 진실 또한 마찬가지다. 행동이나 태도에 따라 활성화의 여부가 결정된다. 앎과 믿음이 얼마나 엉뚱하건, 그래서 각 어떤 의미로 해석되고 재생산되건, 이러한 방식이 의미화 가능성을 넓히는 것은 분명하다.논의에서 분석한 텍스트는 매우 한정적이다. 전문적인 해석이나 입장에...