- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Infective Endocarditis Diagnosis and Management
- Aortic aneurysm repair treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Function and Risk Factors
- Lipoproteins and Cardiovascular Health
- Vascular Procedures and Complications
- Cardiovascular Disease and Adiposity
- Aortic Thrombus and Embolism
- Venous Thromboembolism Diagnosis and Management
- Acute Kidney Injury Research
- Cardiac and Coronary Surgery Techniques
- Folate and B Vitamins Research
- Cardiac Structural Anomalies and Repair
- Acute Ischemic Stroke Management
- Aortic Disease and Treatment Approaches
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 and healthcare impacts
Asan Medical Center
2008-2024
CHA Bundang Medical Center
2016-2024
CHA University
2016-2024
National Health Insurance Service Ilsan Hospital
2023-2024
Korea University Medical Center
2023
Weatherford College
2022
University of Ulsan
2008-2014
Ulsan College
2008-2014
Sejong General Hospital
2012-2014
Kangwon National University
2012-2014
Percutaneous coronary intervention (PCI) is increasingly used to treat unprotected left main artery stenosis, although coronary-artery bypass grafting (CABG) has been considered be the treatment of choice.We randomly assigned patients with stenosis undergo CABG (300 patients) or PCI sirolimus-eluting stents patients). Using a wide margin for noninferiority, we compared groups respect primary composite end point major adverse cardiac cerebrovascular events (death from any cause, myocardial...
Although intravascular ultrasound (IVUS) guidance has been useful in stenting for unprotected left main coronary artery stenosis, its impact on long-term mortality is still unclear.In the MAIN-COMPARE registry, patients with stenosis a hemodynamically stable condition underwent elective under of IVUS (756 patients) or conventional angiography (219 patients). Patients acute myocardial infarction were excluded. The 3-year outcomes between 2 groups primarily compared using propensity-score...
Background— We assessed the optimal intravascular ultrasound (IVUS) stent area to predict angiographic in-stent restenosis (ISR) after sirolimus-eluting implantation for unprotected left main coronary artery (LM) disease. Methods and Results— A total of 403 patients treated with single- or 2-stent strategies (crushing T-stent) had immediate poststenting IVUS 9-month follow-up angiography. Poststenting minimal (MSA) was measured in each 4 segments: ostial anterior descending (LAD), circumflex...
Background— We assessed optimal intravascular ultrasound (IVUS) criteria for predicting functional significance of intermediate coronary lesions. Methods and Results— Overall, 201 patients with 236 lesions underwent IVUS invasive physiological assessment before intervention. Fractional flow reserve (FFR) was measured at maximal hyperemia induced by intravenous adenosine infusion. FFR <0.80 maximum seen in 49 (21%) the overall The independent determinants were minimal lumen area (MLA;...
Objectives and background The impact of underexpansion minimal stent area (MSA) criteria in the second generation drug‐eluting stents (DES) has not been addressed yet. Methods Using intravascular ultrasound (IVUS), we assessed optimal cut‐off values post‐stenting MSA to prevent in‐stent restenosis (ISR). Poststenting IVUS data 9‐month follow‐up angiography were available 912 patients with 990 lesions: 541 sirolimus‐eluting (SES), 220 zotarolimus‐eluting (ZES) 229 everolimus‐eluting (EES)....
Drug-eluting stents significantly improved angiographic and clinical outcomes compared with bare metal in diabetic patients. However, a comparison of everolimus-eluting sirolimus-eluting patients has not been evaluated. Therefore we effectiveness diabetes mellitus.This prospective, multicenter, randomized study stent (n=149) (n=151) implantation The primary end point was noninferiority in-segment late loss at 8 months. Clinical events were also monitored for least 12 Everolimus-eluting...
Background: It is unknown whether the direct oral anticoagulant edoxaban can reduce leaflet thrombosis and accompanying cerebral thromboembolic risk after transcatheter aortic valve replacement. In addition, causal relationship of subclinical with thromboembolism neurological or neurocognitive dysfunction remains unclear. Methods: We conducted a multicenter, open-label randomized trial comparing dual antiplatelet therapy (aspirin plus clopidogrel) in patients who had undergone successful...
There are limited data from randomized trials to guide a specific follow-up surveillance approach after myocardial revascularization. Whether strategy that includes routine functional testing improves clinical outcomes among high-risk patients who have undergone percutaneous coronary intervention (PCI) is uncertain.
Background— Although C-reactive protein (CRP) has been proposed as a useful biomarker for predicting atherothrombosis, the association between CRP and stent thrombosis after drug-eluting implantation not defined. Methods Results— We prospectively evaluated 2691 patients treated with stents who had baseline measurement. The primary outcome was thrombosis; secondary outcomes were death, myocardial infarction (MI), death or MI, target vessel revascularization. During follow-up (median, 3.9...
We evaluated the impact of routine use fractional flow reserve (FFR) on practice and outcomes percutaneous coronary intervention (PCI).Between January 2008 December 2011, rate FFR during PCI increased from 1.9 to 50.7% after introduction (P < 0.001). A total 5097 patients (2699 before 2398 FFR) underwent at an academic hospital in Korea; those, stent implantation was deferred 475 patients. used propensity score (PS) matching compare rates primary endpoint [death, myocardial infarction (MI),...
Background An angiography‐based supervised machine learning ( ML ) algorithm was developed to classify lesions as having fractional flow reserve ≤0.80 versus >0.80. Methods and Results With a 4:1 ratio, 1501 patients with intermediate were randomized into training test sets. Between the ostium 10 mm distal target lesion, series of angiographic lumen diameter measurements along centerline plotted. The 24 computed features based on plot 4 clinical (age, sex, body surface area, involve...
The appropriate follow-up surveillance strategy for patients with acute coronary syndrome (ACS) who have undergone percutaneous intervention (PCI) remains unknown.