A5058591584- Software Engineering Research
- Web Application Security Vulnerabilities
- Software Testing and Debugging Techniques
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
- Education and Learning Interventions
- Laser Applications in Dentistry and Medicine
- Stroke Rehabilitation and Recovery
- CRISPR and Genetic Engineering
- Neonatal and fetal brain pathology
- Diverse Approaches in Healthcare and Education Studies
- Medical Imaging and Pathology Studies
- Fungal and yeast genetics research
- Digital Accessibility for Disabilities
- DNA and Nucleic Acid Chemistry
- Advanced Breast Cancer Therapies
- Security and Verification in Computing
- Barrier Structure and Function Studies
- Hydrogen's biological and therapeutic effects
- Botanical Studies and Applications
- Spam and Phishing Detection
- Agriculture, Soil, Plant Science
- Technology and Data Analysis
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
Creighton University
2022-2023
Pusan National University
2016-2022
Gangneung Asan Hospital
2017
University of Ulsan
2016-2017
Ulsan College
2016-2017
Kangwon National University
2017
Asan Medical Center
2016
Hanyang University
2006-2013
Inje University
2011
Wonkwang University
2004
Photobiomodulation (PBM) has received attention due to its potential for improving tissue function and enhancing regeneration in stroke. A lightweight, compact, simple system of miniaturized electronic devices consisting packaged light-emitting diodes (LEDs) that incorporates a flexible substrate vivo brain PBM mouse model is developed. Using this device platform, the preventive therapeutic effects affixed exposed skull mice photothrombosis middle cerebral artery occlusion stroke are...
Poststroke depression (PSD), which occurs in approximately one-third of stroke survivors, is clinically important because its association with slow functional recovery and increased mortality. In addition, the underlying pathophysiological mechanisms are still poorly understood. We used a mouse model PSD to examine neurobiological beneficial effects aripiprazole, an atypical antipsychotic drug. was induced mice by combining middle cerebral artery occlusion (MCAO) spatial restraint stress....
The isozyme form of eukaryotic initiation factor 4F [eIF-(iso)4F] from wheat germ is composed a p28 subunit that binds the 7-methylguanine cap mRNA and p86 having unknown function. was found to have limited sequence similarity kinesin-like protein encoded by katA gene Arabidopsis thaliana. Native eIF-(iso)4F bacterially expressed p86-p28 complex bound taxol-stabilized maize microtubules (MTs) in vitro. Binding saturation occurred at 1 mol per 5-6 polymerized tubulin dimer, demonstrating...
I- Cre I is a member of the LAGLI-DADG family homing nucleases; however, unlike most members this it contains only single copy signature motif. was over-expressed in Escherichia coli, and simple purification protocol developed that gave reasonably pure protein high yield. Size-exclusion chromatography chemical cross-linking indicated dimer solution. DNA cleavage by absolutely dependent on Mg 2+ (or Mn ), inhibited monovalent cations. displayed surprisingly temperature optimum (>50° C), with...
Cells possess several conserved adaptive mechanisms to respond stress. Stress signaling is initiated reestablish cellular homeostasis, but its effects on the tissue or systemic levels are far less understood. We report that secreted luminal domain of endoplasmic reticulum (ER) stress transducer CREB3L2 (which we name TAILS [transmissible activator increased cell livability under stress]) an endogenous, non-autonomous neuronal resilience. In response oxidative insults, neurons secrete TAILS,...
Fifteen patients underwent computed tomography (CT)-guided contrast material localization of pulmonary nodules, with barium and indigo carmine stain used in five patients, iodized oil five, water-soluble before fluoroscopy-assisted thoracoscopic resection. Contrast was successful all cases, the surgeon confirmed accurate localization, CT-guided is simple useful for
1. The purpose of this paper was to characterize cytochrome P450 (CYP) enzymes involved in N-dealkylation a new oral erectogenic, DA-8159 DA-8164, major circulating active metabolite, human liver microsomes and investigate the inhibitory potential on CYP enzymes.2. CYP3A4 identified as enzyme responsible for DA-8164 based correlation analysis specific inhibitor antibody-mediated inhibition study microsomes, metabolism cDNA expressed enzymes. There is possibility drug-drug interactions when...
Neonatal hypoxic-ischemia (HI) due to insufficient oxygen supply and blood flow during the prenatal postnatal periods can cause cerebral palsy, a serious developmental condition. The purpose of this study was investigate efficacy combining constraint-induced movement therapy (CIMT) electroacupuncture treat rat neonatal HI brain injury.The left common carotid arteries day 7 rats were ligated induce injury, neonates kept in hypoxia chamber containing 8% for 2 hrs. Electroacupuncture at Baihui...
Extrapulmonary small cell carcinoma is a rare neoplasm. It an aggressive malignant tumour characterized by rapid local progression and early metastasis. We report case of arising in the transverse colon 34-year-old man who presented with epigastric pain. On CT, poorly enhancing bulky mass encircling extensive regional lymph node metastases was observed. A segmental annular narrowing thick interhaustral folds found barium enema examination. This first study CT findings extrapulmonary colon.
In this paper, we propose a software vulnerability checker which takes rules describing patterns and source program as input detects locations paths of the in program. Simple flow for vulnerabilities are described specification language designed. The lightweight control data analysis is necessary to detect patterns. Newly discovered can easily be added existing rules. We implement detector three parts: pattern matcher finds program, graph constructor extracts from analyzer program's...
Constraint-induced movement therapy (CIMT) is used in stroke rehabilitation to promote recovery of upper limb motor function. However, its efficacy improving functional outcomes children with hemiplegic cerebral palsy has not been clearly determined clinical or experimental research. The aim our study was assess the a new model CIMT, evaluated terms mortality, stress, and cognitive function rats having undergone neonatal hypoxic-ischemic (HI) brain injury. Neonatal HI injury induced at...
A new dibenzofuran derivative, 1,2,4-trimethoxydibenzofuran-3,9-diol (7), was isolated from the ethyl acetate fraction of Sorbus commixta barks, along with six known compounds, lupeol (1), betulin (2), betulinic acid (3), ursolic (4), -sitosterol (5) and -pyrufuran (6).Their structures were determined by NMR spectroscopic analysis, including 1 H 13 C NMR, H-1 COSY, HSQC HMBC spectra data.Cytotoxic activities seven compounds evaluated in five cancer cell lines, HEp-2, A549, MCF-7, PC-3...
The purpose of this study was to examine the existing level English learning in Korea and China using Metaverse, as well possibilities for future educational developments.This comparative between collected examined two types materials: literature Internet news related research topic order achieve objectives.First, different articles were searched keywords 'Metaverse' 'English', removed duplicate irrelevant articles.Second, researchers 12 Korean 15 Chinese journal articles.Third, from...
Although stroke is among the leading causes of death and long-term disability, there are few effective treatments for limiting severity neurological sequelae. We evaluated effects 29 medicinal herbs listed in Pung chapter 17th century Korean medical text Dongui Bogam on symptoms a mouse model cerebral ischemia.Focal ischemia was induced via photothrombosis. Infarct volume, brain edema, deficits were evaluated. Immunofluorescence staining tight junction proteins aquaporin 4 (AQP4) performed...
Individualized learning is the education that provided at a speed and method appropriate to each learner based on learner's knowledge, interests, so on.This study aimed analyze trends in individualized for general past ten years by dividing them into those from 2012-2016 (Period 1) 2017-2021 2), obtain implications necessary practice school education.After screening, total of 277 studies were analyzed conducting text mining keyword network analysis, using Textom, Ucinet, NetDraw.By process,...