A5055799735- Bacteriophages and microbial interactions
- Plant Virus Research Studies
- Reproductive tract infections research
- Galectins and Cancer Biology
- Immune Cell Function and Interaction
- Cellular transport and secretion
- Parvovirus B19 Infection Studies
- Cellular Mechanics and Interactions
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Insect symbiosis and bacterial influences
- Microtubule and mitosis dynamics
- IL-33, ST2, and ILC Pathways
University of Rochester Medical Center
2019-2022
University of Rochester
2020
Rutgers, The State University of New Jersey
2019
Although platelets are the cellular mediators of thrombosis, they also immune cells. Platelets interact both directly and indirectly with cells, impacting their activation differentiation, as well all phases response. Megakaryocytes (Mks) cell source circulating platelets, until recently Mks were typically only considered bone marrow-resident (BM-resident) However, platelet-producing reside in lung, lung express greater levels molecules compared BM Mks. We therefore sought to define...
ABSTRACT Adherens junctions provide attachments between neighboring epithelial cells and a physical link to the cytoskeleton, which enables them sense transmit forces initiate biomechanical signaling. Examination of Ajuba LIM protein Jub in Drosophila embryos revealed that it is recruited adherens tissues experiencing high levels myosin activity, pattern recruitment varies depending upon how tension organized. In with junctional myosin, puncta near intercellular vertices, are distinct from...
The female reproductive tract (FRT) microbiome plays a vital role in maintaining vaginal health. Viruses are key regulators of other microbial ecosystems, but little is known about how the FRT viruses (virome), particularly bacteriophages that comprise phageome, impact health and dysbiosis. We hypothesize bacterial vaginosis (BV) associated with altered phageome diversity, transkingdom interplay, bacteriophage discriminate taxa. Here, we conducted retrospective, longitudinal analysis swabs...
Zika virus (ZIKV) is one of the recently emerging vector-borne viruses in humans and responsible for severe congenital abnormalities such as microcephaly Western Hemisphere. Currently, only a few vaccine candidates therapeutic drugs are being developed treatment ZIKV infections, yet none commercially available. The polyanionic aromatic compound aurintricarboxylic acid (ATA) has been shown to have broad-spectrum antimicrobial antiviral activity. In this study, we evaluated ATA potential drug...
Abstract The female reproductive tract (FRT) microbiome plays an important role in maintaining vaginal health. Viruses play a key regulating other microbial ecosystems, but little is known about how the FRT viruses (virome), particularly bacteriophages, impacts health and dysbiosis. We hypothesize that bacterial vaginosis associated with alterations virome, these changes correlate bacteriome shifts. conducted retrospective, longitudinal analysis of swabs collected from 54 (BV)-positive 46...