A5042259643- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Radiation Dose and Imaging
- Advanced MRI Techniques and Applications
- Advanced X-ray and CT Imaging
- MRI in cancer diagnosis
- Radiation Therapy and Dosimetry
- Lung Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Advances in Oncology and Radiotherapy
- Pancreatic and Hepatic Oncology Research
- Meningioma and schwannoma management
- Vascular Malformations Diagnosis and Treatment
- Medical Image Segmentation Techniques
- Breast Cancer Treatment Studies
- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Atomic and Subatomic Physics Research
- Ultrasound and Hyperthermia Applications
- Brain Metastases and Treatment
- Delphi Technique in Research
- Breast Lesions and Carcinomas
- Radiopharmaceutical Chemistry and Applications
- Anatomy and Medical Technology
Azienda Ospedaliera Universitaria Integrata Verona
2015-2025
University of Verona
2012-2023
American Association of Physicists in Medicine
2017-2021
Ashland (United States)
2017-2021
John Wiley & Sons (United States)
2018-2021
Duke Medical Center
2020-2021
Johns Hopkins University
2019-2021
Wake Forest University
2021
Swedish Medical Center
2018-2020
UPMC Health System
2019-2020
The task group (TG) for quality assurance robotic radiosurgery was formed by the American Association of Physicists in Medicine's Science Council under direction Radiation Therapy Committee and Quality Assurance (QA) Subcommittee. (TG-135) had three main charges: (1) To make recommendations on a code practice Robotic Radiosurgery QA; (2) dosimetric verification techniques, especially regard to real-time respiratory motion tracking software; (3) issues which require further research...
The scope of this study was to estimate total scatter factors ͑s c,p ͒ the three smallest collimators Cyberknife radiosurgery system ͑5-10 mm in diameter͒, combining experimental measurements and Monte Carlo simulation.Two microchambers, a diode, diamond detector were used collect data.The treatment head detectors simulated by means code order calculate correction for consistency check between measurement simulation.Results were: s ͑5 mm͒ = 0.677± 0.004, ͑7.5 0.820± 0.008, ͑10 0.871± all...
To present initial, short-term results obtained with an image-guided radiosurgery apparatus (CyberKnife; Accuray, Inc., Sunnyvale, CA) in a series of 199 benign intracranial meningiomas.Selection criteria included lesions unsuitable for surgery and/or remnants after partial surgical removal. All patients were either symptomatic harboring growing tumors. Ninety-nine tumors involved the cavernous sinus; 28 posterior fossa, petrous bone, or clivus; and 29 contact anterior optic pathways....
The dosimetry of the fields usually employed in radiosurgery requires use small detectors to measure Total Scatter Factor (Sc,p), Tissue Maximum Ratio (TMR), Percentage Depth Dose (PDD), and Off Axis (OAR). In this paper new dosimeters are investigated: a type radiochromic film, micro parallel-plate chamber (filled with both air tetramethylsilane, TMS), MOSFETs, TLD-800 microcubes. Their behavior has been compared response radiographic film values obtained BEAM Monte Carlo simulation....
In the era of precision medicine, increasing importance is given to machine learning (ML) applications. breast cancer, advanced analyses, such as radiomic process, characterise tumours and predict therapy responses. Breast magnetic resonance imaging (MRI) plays a key role in screening, staging, treatment monitoring. Lesion segmentation on MRI essential both assess tumour growth baseline for feature extraction. Manual time-consuming prone inter-operator variability, limiting access large...
The authors describe a method that utilizes an image-guided robotic radiosurgical apparatus (the CyberKnife) for treatment of cerebral arteriovenous malformations (AVMs). This procedure required the development original technique allows high degree automation.Angiographic images were imported into planning software by coregistering CT and 3D rotational angiography. nidus contour was delineated using contouring tools system. Functional MR imaging employed critical cortical regions, such as...
The purpose of this work is to compare the photon dose calculation a commercially available three‐dimensional (3D) treatment planning system based on collapsed cone convolution technique against BEAM, Monte Carlo code that allows detailed simulation radiotherapy accelerator. first part devoted commissioning BEAM for 6 MV beam and optimization linac description fit experimental data. This step also involves comparison with radiochromic film data an inhomogeneous phantom built simulate...
Spatial accuracy in extracranial radiosurgery is affected by organ motion. Motion tracking systems may be able to avoid PTV enlargement while preserving treatment times, however special attention needed when fiducial markers are used identify the target can move with respect organs at risk (OARs). Ten patients treated means of Synchrony system were taken into account. Sparing irradiated volume and complication probability estimated calculating plans a motion (Cyberknife Synchrony, Sunnyvale,...
Objectives To test whether 3T MRI radiomics of breast malignant lesions improves the performance predictive models complete response to neoadjuvant chemotherapy when added other clinical, histological and radiological information. Methods Women who consecutively had pre-neoadjuvant (NAC) DCE-MRI between January 2016 October 2019 were retrospectively included in study. 18F-FDG PET-CT information obtained through lesion biopsy also available. All patients underwent surgery specimens analyzed....
Abstract Purpose To classify COVID-19, COVID-19-like and non-COVID-19 interstitial pneumonia using lung CT radiomic features. Material Methods data of 115 patients with respiratory symptoms suspected for COVID-19 disease were retrospectively analyzed. Based on the results nasopharyngeal swab, divided into two main groups, positive (C +) negative (C−), respectively. C− patients, however, presented involvement. A subgroup C−, (CL), considered as highly suggestive COVID at CT. Radiomic features...
Object. Radiosurgical treatment of a cerebral arteriovenous malformation (AVM) requires the precise definition nidus lesion in stereotactic space. This cannot be accomplished using simple angiography, but combination biplanar angiographic images and contrast-enhanced computerized tomography (CT) scans. In present study authors describe method which three-dimensional (3D) rotational angiography is integrated into space to aid planning for radiosurgery. Methods. Twenty patients harboring AVMs...
The scope of this work was to apply a method for estimation total scatter factors the smallest beams Cyberknife radiosurgery system newly available solid-state detectors: PTW 60008 diode, SunNuclear EdgeDetector and Thomson Nielsen TN502RDM micromosfet. is based on consistency check between Monte Carlo simulation detectors experimental results, described in recent publication. Corrected were excellent agreement with findings former study. results showed that diodes tend overestimate factor...
Functional magnetic resonance imaging (fMRI) is used to distinguish areas of the brain responsible for different tasks and functions. It possible, example, by using fMRI images, identify particular regions in which can be considered as "functional organs at risk" (fOARs), i.e., would cause significant patient morbidity if compromised. The aim this study propose validate a method exploit functional information identification fOARs CyberKnife (Accuray, Inc., Sunnyvale, CA) radiosurgery...
The aim of this study was to assess the ability Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (18F-FDG PET/CT) provide functional information useful in predicting pathological response an intensive neoadjuvant chemo-radiotherapy (nCRT) protocol for both esophageal squamous cell carcinoma (SCC) and adenocarcinoma (ADC) patients.Esophageal (EC) patients, treated our Center between 2014 2018, were retrospectively reviewed. nCRT schedule consisted induction phase weekly...
To assess the dosimetric feasibility of a stereotactic body radiotherapy (SBRT) dose escalated protocol, with simultaneous integrated boost (SIB) and protection (SIP) approach, in patients locally advanced pancreatic cancer (LAPC).Twenty LAPC lesions, previously treated SBRT at our Institution, were re-planned. The original prescribed administered was 50/30/25 Gy five fractions to PTVsib (tumor-vessel interface [TVI])/PTVt (tumor volume)/PTVsip (overlap area between PTVt planning organs risk...