A5020527422- Mass Spectrometry Techniques and Applications
- Laser Design and Applications
- Analytical Chemistry and Chromatography
- Metabolomics and Mass Spectrometry Studies
- Spectroscopy and Laser Applications
- Advanced Proteomics Techniques and Applications
- Advanced Chemical Sensor Technologies
- Advanced Chemical Physics Studies
- Laser-induced spectroscopy and plasma
- Microfluidic and Capillary Electrophoresis Applications
- Indoor Air Quality and Microbial Exposure
- Electrowetting and Microfluidic Technologies
- Advancements in Photolithography Techniques
- Thermodynamic properties of mixtures
- Chemical Thermodynamics and Molecular Structure
- Economic Development and Digital Transformation
- Photochemistry and Electron Transfer Studies
- Spectroscopy and Quantum Chemical Studies
- Innovative Teaching Methods
- Nicotinic Acetylcholine Receptors Study
- Electron and X-Ray Spectroscopy Techniques
- Innovative Teaching and Learning Methods
- Economic Growth and Productivity
- Atomic and Molecular Physics
- Polymer composites and self-healing
Virginia Innovation Partnership Corporation
2018-2024
Vanderbilt University
2018-2024
Brigham Young University
1988-2020
University of North Carolina at Chapel Hill
2015-2017
Communities In Schools of Orange County
2015
Southern Illinois University Edwardsville
2009-2010
Kirtland Air Force Base
1975
E-cigarettes are generally thought of as a safer smoking alternative to traditional cigarettes. However, little is known about the effects e-cigarette liquids (e-liquids) on lung. Since over 7,000 unique flavors have been identified for purchase in United States, our goal was conduct screen that would test whether different flavored e-liquids exhibited toxicant profiles. We tested 13 [with nicotine and propylene glycol/vegetable glycerin (PG/VG) serving controls] lung epithelial cell line...
The increasing focus on lipid metabolism has revealed a need for analytical techniques capable of structurally characterizing lipids with high degree specificity. Lipids can exist as any one large number double bond positional isomers, which are indistinguishable by single-stage mass spectrometry alone. Ozonolysis reactions coupled to have previously been demonstrated means localizing bonds in unsaturated lipids. Here we describe an online, solution-phase reactor using ozone produced via...
Lipids are structurally diverse molecules that play a pivotal role in plethora of biological processes. However, deciphering the roles specific lipids is challenging due to existence numerous isomers. This high chemical complexity lipidome one major challenges lipidomics research, as traditional liquid chromatography-mass spectrometry (LC-MS) based approaches often not powerful enough resolve these isomeric and isobaric nuances within complex samples. Thus, uniquely suited benefits provided...
The effect of the molecular‐weight distribution polymethyl methacrylate on its performance as a resist material for electron beam exposure is investigated with aid gel‐permeation chromatography. solubility PMMA in developer comprising 3:1 ratio isopropyl alcohol to methyl isobutyl ketone determined, and need post‐development washing substrates shown be due, part, liberation insoluble polymer molecules from film during development. Removal very high molecular weight molecules, which are...
The complexity of the lipidome has necessitated development novel analytical approaches for identification and structural analysis morphologically diverse classes lipids. At this time, a variety dissociation techniques have been utilized to probe lipid decomposition pathways in search structurally diagnostic fragment ions. Here, we investigate application surface-induced (SID), fragmentation technique that imparts energy target molecule via collision with coated surface, seven lipids across...
Differential ion mobility spectrometry (DIMS) separates ions based on differences in their mobilities low and high electric fields. When coupled to mass spectrometric analyses, DIMS has the ability improve signal-to-background by eliminating isobaric isomeric compounds for analytes complex mixtures. separation power, often measured resolution peak capacity, can be improved through increasing fraction of helium nitrogen carrier gas. However, because is higher helium, a greater number collide...
Differential ion mobility spectrometry (DIMS) separations are described using similar terminology to liquid chromatography, capillary electrophoresis, and drift tube spectrometry. The characterization comparison of all these typically explained in terms resolving power, resolution, and/or peak capacity. A major difference between is that DIMS space whereas the others time. However, time can, theory, be extended infinitely, space, such as separations, constrained by physical dimensions...
Commercial-grade polymer synthesis is performed via melt polymerization, which leads to polydispersion. The work reported herein provides a synthetic strategy produce mono-dispersive polyurethane oligomers and an analytical distinguish these oligomers, providing chemists with the tools necessary synthesize identify specific structures that exhibit desired property.Three isomeric poly(ethylene glycol)-polyurethane (PEG-PUR) were synthesized analyzed flow-injection ion mobility mass...
We describe a device intended for pumping fluids through nanoscale channels. The nanofluidic pump is created from flexible silica membranes grown chemical vapor deposition and actuated electrostatic force. A packaging technique using dry film to create fluid interfaces demonstrated.
A temperature dependence for CO optical broadening cross sections is derived and shown to agree with values determined from experimentally measured self-broadened half-widths. It emphasized that accurate are essential in computer modeling of laser performance.
Even though scientific communication and collaboration play critical roles in academic success, they often come second to teaching laboratory fundamentals. COVID-19 associated capacity constraints forced our program reexamine the traditional instruction paradigm by limiting physical attendance, as well duration. Instead, we opted turn these restrictions into opportunities study peer-to-peer a means enhance in-person experimentation. Here, two-week high performance liquid gas chromatography...