A5026960863- Mitochondrial Function and Pathology
- Adipose Tissue and Metabolism
- Themes in Literature Analysis
- ATP Synthase and ATPases Research
- HIV/AIDS Research and Interventions
- Cardiac Ischemia and Reperfusion
- Tuberculosis Research and Epidemiology
- HIV/AIDS Impact and Responses
- Neuroinflammation and Neurodegeneration Mechanisms
- Metabolism and Genetic Disorders
Lund University
2014-2024
Kungälvs Sjukhus
2024
Abstract Mitochondrial dysfunction is considered a hallmark of aging. Up to now, gradual decline mitochondrial respiration with advancing age has mainly been demonstrated in human muscle tissue. A handful studies have examined age-related blood cells, and only small sample sizes platelets. In this study, we analyzed peripheral mononuclear cells (PBMCs) platelets from 308 individuals across the lifespan (0–86 years). regression analyses, adjustment for false discovery rate (FDR), found...
There is a growing interest for the possibility of using peripheral blood cells (including platelets) as markers mitochondrial function in less accessible tissues. Only few studies have examined correlation between respiration and muscle tissue, with small sample sizes conflicting results.This study investigated within across Additional analyses were performed to elucidate which cell type would be most useful assessing systemic function.There was significant but weak tissue platelets...
The Ethiopian epidemic is currently on the wane. However, situation for infected children in some ways lagging behind due to low treatment coverage and deficient prevention of mother-to-child transmission. Too few studies have examined HIV presenting care low-income countries general. Considering presence local variations nature a study Ethiopia could be special value continuing fight against HIV. aim this describe main characteristics with at district hospital resource-limited area southern...