Cardiovascular Magnetic Resonance (CMR) enables non-invasive quantification of cardiac output (CO) and thereby index (CI, CO indexed to body surface area). The aim this study was establish if CI decreases with age compare the values for athletes patients congestive heart failure (CHF). measured in 144 healthy volunteers (39 ± 16 years, range 21–81 68 females), 60 (29 6 30 females) 157 CHF ejection fraction (EF) below 40% (60 13 33 females). calculated using aortic flow by velocity-encoded...

Intracardiac blood flow is driven by hemodynamic forces that are exchanged between the and myocardium. Previous studies have been limited to 2D measurements or investigated only left ventricular (LV) forces. Right (RV) their mechanistic contribution asymmetric redirection of in RV not measured. We therefore aimed quantify 3D both ventricles a cohort healthy subjects, using magnetic resonance imaging 4D measurements. Twenty five controls, 14 elite endurance athletes, 2 patients with LV...

The kinetic energy (KE) of intracardiac blood may play an important role in cardiac function. aims the present study were to 1) quantify and investigate determinants KE, 2) compare KE expenditure between athletes control subjects, 3) amount inside outside diastolic vortex. Fourteen fourteen volunteers underwent MRI, including four-dimensional phase-contrast sequences. was quantified four chambers, calculated by determining mean KE/cardiac index. Left ventricular (LV) mass independent...

Respiratory gating is often used in 4D-flow acquisition to reduce motion artifacts. However, increases scan time. The aim of this study was investigate if respiratory can be excluded from 4D flow acquisitions without affecting quantitative intracardiac parameters. Eight volunteers underwent CMR at 1.5 T with a 5-channel coil (5ch). Imaging included 2D measurements and whole-heart (Resp(+), Resp(−)). Stroke volume (SV), particle-trace volumes, kinetic energy, vortex-ring were obtained...

Introduction. Manual delineation of the left ventricle is clinical standard for quantification cardiovascular magnetic resonance images despite being time consuming and observer dependent. Previous automatic methods generally do not account one major contributor to stroke volume, long-axis motion. Therefore, aim this study was develop validate an algorithm time-resolved segmentation covering whole ventricle, including basal slices affected by Methods. Ninety subjects imaged with a cine...

Summary Background Whereas ventricular filling has been extensively studied and debated, atrial is less well characterized. Therefore, the aim of this study was to quantify secured during diastole systole, investigate whether depends on heart rate ( HR ) total volume THV ). Methods Thirty‐two athletes (16 women) 32 normal subjects underwent cardiac magnetic resonance imaging. Cardiac volumes atrioventricular plane displacement AVPD were determined. Longitudinal radial contribution stroke...

Atrioventricular plane displacement (AVPD) is an indicator for systolic and diastolic function accounts 60% of the left ventricular, 80% right ventricular stroke volume. AVPD commonly measured clinically in echocardiography as mitral tricuspid annular excursion (MAPSE TAPSE), but has not been applied widely cardiovascular magnetic resonance (CMR). To date, there no robust automatic algorithm available that allows to be CMR with input a single timeframe. This study aimed develop, validate...

Background Fetal cardiovascular MRI complements ultrasound to assess fetal pathophysiology. Purpose To develop a free‐breathing method for retrospective cine using Doppler (DUS) cardiac gating and tiny golden angle radial sampling (tyGRASP) accelerated acquisition capable of detecting movements motion compensation. Study Type Feasibility study. Subjects Nine volunteers (gestational week 34–40). Short‐axis four‐chamber views were acquired during maternal breath‐hold. Field Strength/Sequence...

Septal systolic motion is towards the left ventricle (LV) in healthy hearts. Patients with pulmonary regurgitation (PR) and right ventricular (RV) volume overload have septal toward RV. This may affect longitudinal contribution from atrioventricular plane displacement (AVPD) lateral to stroke (SV). The study aimed quantify these contributions SV patients PR. Cardiac magnetic resonance imaging was used for assessment of cardiac volumes. (n = 30; age 9-59 yr) PR due surgically corrected...

The prevalence of atrial fibrillation (AF) in active astronauts is ≈5%, similar to the general population but at a younger age. Risk factors for AF include left enlargement, increased number premature complexes, and certain parameters on signal-averaged electrocardiography, such as P-wave duration, root mean square voltage terminal 20 ms P wave, amplitude. We aimed evaluate changes structure, supraventricular beats, electrophysiology determine whether spaceflight could increase risk...

The geometrical relationship between atrial and ventricular short-axis cross-sectional area determines the hydraulic forces acting on intracardiac blood. This is important for diastolic filling. In patients undergoing heart transplantation (HTx), left atrium often enlarged as a result of standard surgical technique. We hypothesized that filling in HTx affected by surgery altering ventricle.

The effects on left and right ventricular (LV, RV) volumes during physical exercise remains controversial. Furthermore, no previous study has investigated the of longitudinal contribution to stroke volume (SV) outer variation heart. aim this was determine if LV, RV total heart (THV) as well cardiac pumping mechanisms change compared rest using cardiovascular magnetic resonance (CMR). 26 healthy volunteers (6 women) underwent CMR at exercise. Exercise performed a custom built ergometer for...

Introduction. Manual delineation of the left ventricle is clinical standard for quantification cardiovascular magnetic resonance images despite being time consuming and observer dependent. Previous automatic methods generally do not account one major contributor to stroke volume, long-axis motion. Therefore, aim this study was develop validate an algorithm time-resolved segmentation covering whole ventricle, including basal slices affected by Methods. Ninety subjects imaged with a cine...

Fetal cardiovascular magnetic resonance (CMR) imaging is used clinically and for research, but has been previously limited due to lack of direct gating methods. A CMR-compatible Doppler ultrasound (DUS) device resolved this. However, the DUS-gating method not validated against current reference fetal phase-contrast blood flow measurements, metric optimized (MOG). Further, we investigated how different methods vessel delineation affect volumes observer variability in acquisitions.

To develop more sensitive measures of impaired cardiac function in patients with pulmonary hypertension (PH), since detection right ventricular (RV) is important these patients. With the hypothesis that a change septal PH associated altered longitudinal and lateral both ventricles, as compensatory mechanism, we quantified contributions parameters to stroke volume (SV) ventricles using magnetic resonance (CMR). Seventeen (10 females) evaluated for underwent heart catheterization (RHC) CMR....

There is a growing interest for the possibility of using peripheral blood cells (including platelets) as markers mitochondrial function in less accessible tissues. Only few studies have examined correlation between respiration and muscle tissue, with small sample sizes conflicting results.This study investigated within across Additional analyses were performed to elucidate which cell type would be most useful assessing systemic function.There was significant but weak tissue platelets...

The majority (60%) of left ventricular (LV) stroke volume (SV) is generated by longitudinal shortening causing apical atrioventricular plane displacement (AVPD) in systole. remaining SV caused radial inward motion the epicardium both septal and lateral wall. We aimed to determine if these longitudinal, contributions LVSV are changed patients with chronic myocardial infarction (MI). Patients a (>3 months) ST-elevation MI anterior descending (LAD, n = 20) or right coronary artery (RCA, 16)...

Blood flow measurements in the ascending aorta and pulmonary artery from phase-contrast magnetic resonance images require accurate time-resolved vessel segmentation over cardiac cycle. Current semi-automatic methods often involve time-consuming manual correction, relying on user experience for results. The purpose of this study was to develop a algorithm with shape constraints based delineations robust artery, evaluate proposed method healthy volunteers patients heart failure congenital...

Abstract Background Preterm birth and fetal growth restriction (FGR) are associated with structural functional kidney changes, increasing long-term risk for chronic disease hypertension. However, recent studies in preterm children conflicting, indicating changes but normal function. This study therefore assessed structure function a cohort of adolescents born very without verified FGR. Methods Adolescents FGR two groups appropriate birthweight (AGA) were included; one matched gestational...

Investigate ventricular and atrial remodeling following septal defect (ASD) closure examine if pulmonary-to-systemic flow ratio (QP/QS) right (RV) volume predict improvement, determined as percentage of predicted oxygen uptake (VO2%). Long-term cardiovascular magnetic resonance (CMR) data on after ASD-closure is limited treatment effect exercise capacity debated. Sixteen patients undergoing transcatheter ASD 16 age sexmatched controls were studied. CMR was performed before treatment, the day...

The purpose of this study was to determine the effect stress on left-to-right shunting in patients with atrial septal defect (ASD) and investigate if degree shunting, cardiac output (CO), right ventricular (RV) volumes are related exercise capacity. Twenty-six a secundum ASD 16 healthy volunteers were studied rest/stress magnetic resonance using 20 µg/kg/min dobutamine 0.25–0.75 mg atropine quantify CO, pulmonary systemic flow ratio (QP/QS), left (LV) RV volumes. Peak oxygen uptake (VO2peak)...