B. Lira De Leon

ORCID: 0000-0001-7734-9321
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About
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Research Areas
  • Childhood Cancer Survivors' Quality of Life
  • Cell Adhesion Molecules Research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Platelet Disorders and Treatments
  • Phagocytosis and Immune Regulation
  • Venous Thromboembolism Diagnosis and Management
  • Acute Myocardial Infarction Research
  • Acute Myeloid Leukemia Research
  • Blood Coagulation and Thrombosis Mechanisms
  • Neonatal Respiratory Health Research
  • Hematopoietic Stem Cell Transplantation
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiovascular Health and Disease Prevention
  • Neutropenia and Cancer Infections

Indiana University School of Medicine
2021-2024

Indiana University – Purdue University Indianapolis
2024

Indiana University
2021

University School
2021

Aims & Objectives: Children with cancer are a high risk population for adverse outcomes during critical Ilness. In this study, we aim to describe children admitted the pediatric intensive care unit (PICU) and identify potential factors outcomes. Methods: We conducted retrospective cohort study of all PICU admissions in dedicated children´s hospital Mexico between December 2013 2019. Patients without those transferred outside facilities were excluded. Clinical extracted from medical record....

10.1097/01.pcc.0000739416.17707.bb article EN Pediatric Critical Care Medicine 2021-03-01

Aims & Objectives: The principal aim of this study is to describe clinical features and frequency presentation known risk factors for thrombosis in children with cancer during stay a pediatric intensive care unit. Methods: A retrospective design the was established. Patients diagnosis their PICU were identified from October 2014 January 2020 single oncology center Mexico. Clinical risks factor found on medical record. Descriptive analysis findings performed. Results: prevalence 1.9% 8...

10.1097/01.pcc.0000738884.55509.9c article EN Pediatric Critical Care Medicine 2021-03-01

Aims & Objectives: Hepatic Sinusoidal obstruction syndrome (SOS/VOD) is a toxic complication common after stem cell transplant (HSCT). It may also occur chemotherapy without HSCT. We present two cases who developed severe SOS/VOD with multiorgan dysfunction (MODS) chemotherapy. Methods: Retrospective case and literature review. Results: Patient 1 was 3-month-old male infantile fibrosarcoma. He received actinomycin vincristine days prior. admitted to PICU for sepsis quickly developing...

10.1097/01.pcc.0000741188.35238.f1 article EN Pediatric Critical Care Medicine 2021-03-01

Introduction: Migration of leukocytes in response to chemical gradients, chemotaxis, is dependent on many factors, including cell type, surface markers, the chemoattractant, etc. Sphinogsine-1-phosphate (S1P) a chemoattractant playing large role migrating activated T cells out lymph nodes by binding their S1P receptor, S1P1. The importance egress from highlighted pharmacological disruption this migration can lead immune dampening and thus control multiple sclerosis, an autoimmune disease. In...

10.18060/25859 article EN Proceedings of IMPRS 2021-12-10
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