Bacterial cellulose (BC) is a polymer obtained by fermentation with microorganism of different genera. Recently, new producer species have been discovered, which require identification the most important variables affecting production. In this work, influence carbon sources in BC production novel low pH-resistant strain Komagataeibacter medellinensis was established. The Hestrin-Schramm culture medium used as reference and compared to other media comprising glucose, fructose, sucrose, at...

Bacterial nanocellulose (BNC) is a promising biomedical material. However, the haemocompatibility (haemolysis and thrombogenicity) acute sub-chronic immune responses to three-dimensional (3D) BNC biomaterials have not been evaluated. Accordingly, this manuscript focused on effect of 3D microporosity comparison with 2D architecture, followed by evaluation response BNC. Blood ex vivo studies indicated that compared other architectures, never-dried presented antihemolytic antithrombogenic...

Abstract Despite the efforts focused on manufacturing biological engineering scaffolds for tissue and regenerative medicine, a biomaterial that meets necessary characteristics these applications has not been developed to date. Bacterial nanocellulose (BNC) is an outstanding medicine; however, BNC's have two‐dimensional (2D) medical devices, such as wound dressings. Given need three‐dimensional (3D) porous biomaterials, this work evaluates two methods generate BNC scaffolds. The structural...

Abstract Cellulose from vegetable sources is the most abundant biopolymer on earth. In plants, cellulose a reinforcement element that conforms to hierarchical structure. micro-/nanofibers can be isolated cell wall by top-down strategies involving mechanical processes used in applications as reinforcing material. Nonetheless, its use has been limited extraction an aqueous medium unfavorable when employed low-hydrophilic matrices. Therefore, this work proposes novel homogenization route which...

Bacterial nanocellulose (BNC) has a negative surface charge in physiological environments, which allows the adsorption of calcium ions to initiate nucleation different phosphate phases. The aim this study was investigate methods mineralization three-dimensional microporous bacterial with intention mimicking composition, structure, and biomechanical properties natural bone. To generate 3D biomaterial, porogen particles were incorporated during BNC fermentation Komagataeibacter medellinensis...

Colorectal Cancer (CRC) ranks third in terms of incidence and second mortality prevalence worldwide. In relation to chemotherapy treatment, the most used drug is 5-fluorouracil (5-FU); however, use this generates various toxic effects at systemic level. For reason, new therapeutic strategies are currently being sought that can be as neoadjuvant or adjuvant treatments. Recent research has shown natural compounds, such genistein, have chemotherapeutic anticancer effects, but mechanisms action...

We investigated wound dressing composites comprising fibrils of bacterial cellulose (BC) grown by fermentation in the presence polyvinyl alcohol (PVA) followed physical crosslinking. The reference biointerface, neat BC, favoured adhesion fibroblasts owing to size exclusion effects. Furthermore, it resisted migration across biomaterial. Such effects were minimized case PVA/BC membranes. Therefore, latter are suggested cases where cell is be avoided, for instance, design interactive dressings...

Genistein is an isoflavone with antioxidant, anti-inflammatory, and anticancer properties. That said, its use in the industry limited by low solubility aqueous systems. In this work, bacterial nanocellulose (BNC) BNC modified cetyltrimethylammonium (BNC-CTAB) were evaluated as genistein-encapsulating materials for their controlled release cancer chemoprevention. Thin films obtained characterized contact angle, AFM, TEM, UV-Vis spectroscopy FTIR, TGA techniques to verify surface modification...

Neste trabalho são apresentados os resultados da síntese de nanocompósitos baseados em amido termoplástico (TPS) reforçado com nanofitas celulose bacteriana (BC).A foi feita por fermentação in situ e formação ligações cruzadas.A para a obtenção das conduzida sete dias empregando bactéria colombiana nativa Gluconacetobacter medellinenses; foram plasticizados glicerol as cruzadas formadas ácido cítrico.Os obtidos depois destes caracterizados análise termogravimétrica (TGA), espectroscopia na...

Bacterial nanocellulose, a natural hydrocolloid traditionally used as food ingredient, has demonstrated potential non-soluble dietary fiber and functional material. Moreover, its properties can further be potentialized whether coupled with anthocyanins to endow antioxidant activity. Vaccinium meridionale swartz extract (VE), rich in anthocyanins, recently effects against colorectal cancer; therefore, encapsulating it into bacterial nanocellulose (BNC) may offer an enhanced VE delivery...

Bacterial nanocellulose (BNC) is a novel nanomaterial known for its large surface area, biocompatibility, and non-toxicity. BNC contributes to regenerative processes in the skin but lacks antimicrobial anti-inflammatory properties. Herein, development of bioactive wound dressings by loading antibacterial povidone-iodine (PVI) or acetylsalicylic acid (ASA) into bacterial cellulose presented. produced using Hestrin–Schramm culture media loaded via immersion PVI ASA. Through scanning electron...

Bacterial nanocellulose (BNC) surface has a negative charge that allows the adsorption of calcium ions to initiate nucleation different phosphate phases. The aim this study was investigate methods mineralization on three-dimensional microporous bacterial nanocellulose, mimetize composition, structure, and biomechanical properties natural bone. To generate 3D biomaterial, porogen particles were incorporated during BNC fermentation with strain Komagataeibacter medellinensis. Calcium phosphates...

Los materiales poliméricos han tenido una imagen desfavorable, ya que son asociados con contaminación. Sin embargo, estos de gran importancia para la biomedicina. polímeros muy versátiles, se pueden obtener múltiples configuraciones químicas y mezclas generar compuestos propiedades sinérgicas. En esta investigación realizó un análisis científico tecnológico las aplicaciones biomédicas biomateriales recopila algunas sus aplicaciones, mecánicas características importantes industria biomédica....