A5024120998- Vibrio bacteria research studies
- Escherichia coli research studies
- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Aquatic Ecosystems and Biodiversity
- Child Nutrition and Water Access
- Antibiotic Resistance in Bacteria
- Enterobacteriaceae and Cronobacter Research
Johns Hopkins University
2018
Background For almost 50 years sub-Saharan Africa, including Uganda, has experienced several outbreaks due to Vibrio cholerae. Our aim was determine the genetic relatedness and spread of strains responsible for cholera in Uganda. Methodology/Principal findings Sixty-three V. cholerae isolates collected from Uganda between 2014 2016 were tested using multiplex polymerase chain reaction (PCR), multi-locus variable number tandem repeat analysis (MLVA) whole genome sequencing (WGS). Three...
Cholera is a major public health problem in the African Great Lakes basin. Two hypotheses might explain this observation namely; lakes are reservoirs of toxigenic V. cholerae O1 and O139 bacteria or cholera outbreaks result repeated pathogen introduction from neighboring communities / countries but facilitate introductions. A prospective study was conducted Uganda between February 2015 January 2016 which 28 selected surface water sources were tested for presence species using rapid test...
Enterotoxigenic Escherichia Coli (ETEC) is an important cause for diarrheal disease in children and travelers globally. Epidemiological data on the distribution of strains ETEC associated colonization factors (CFs) evaluation candidate vaccines. We used conventional PCR quantitative to screen toxins CFs using DNA extracted from stool samples which tested positive Luminex GPP panel collected presenting with moderate severe diarrhea at selected health facilities Lusaka. 49/106 (46.2%) were...