A5006444626- Vibrio bacteria research studies
- COVID-19 epidemiological studies
- Child Nutrition and Water Access
- Influenza Virus Research Studies
- Salmonella and Campylobacter epidemiology
- Travel-related health issues
- Vaccine Coverage and Hesitancy
- Disaster Response and Management
- Viral Infections and Outbreaks Research
- Antibiotic Resistance in Bacteria
- Viral Infections and Vectors
- SARS-CoV-2 and COVID-19 Research
- Blood donation and transfusion practices
- Global Maternal and Child Health
- Aquatic Ecosystems and Biodiversity
- Pneumonia and Respiratory Infections
- Pharmaceutical Economics and Policy
- Tuberculosis Research and Epidemiology
- Genomics and Phylogenetic Studies
- Poverty, Education, and Child Welfare
- Malaria Research and Control
- Health Systems, Economic Evaluations, Quality of Life
- Alcoholism and Thiamine Deficiency
- Health and Conflict Studies
- Immune responses and vaccinations
Ministry of Health
2016-2025
Makerere University
2015-2025
Integrated Oncology (United States)
2021
World Health Organization - Pakistan
2018
World Health Organization - Egypt
2018
Médecins Sans Frontières
2018
Johns Hopkins University
2018
Federal Ministry of Health
2018
Institut Pasteur
2018
World Health Organization
2018
In December 2019, a new coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and associated disease, coronavirus disease 2019 (COVID-19), was identified in China. This virus spread quickly March, 2020, it declared pandemic. Scientists predicted the worst scenario to occur Africa since least developed of continents terms human development index, lagged behind others achievement United Nations sustainable goals (SDGs), has inadequate resources for provision social...
Marburg hemorrhagic fever was detected among 4 miners in Ibanda District, Uganda, from June through September, 2007. Infection likely acquired exposure to bats or bat secretions a mine Kamwenge and possibly human-to-human transmission between some patients. We describe the epidemiologic investigation health education response.
We conducted a survey involving 1,604 households to determine community care-seeking patterns and 163 exit interviews appropriateness of treatment common childhood illnesses at private sector drug shops in two rural districts Uganda. Of children sick within the last 2 weeks, 496 (53.1%) first sought versus 154 (16.5%) government health facility. Only 15 (10.3%) febrile treated received appropriate for malaria. Five (15.6%) with both cough fast breathing amoxicillin, although no 5–7 days....
Cross-border cholera outbreaks are a major public health problem in Sub-Saharan Africa contributing to the high annual reported cases and deaths. These affect all categories of people challenging prevent control. This article describes lessons learnt during cross-border outbreak control Eastern Southern sub-regions using case Uganda-DRC Malawi-Mozambique borders makes recommendations for future prevention control.We reviewed weekly surveillance data, response reports documented experiences...
Abstract Background Water is the most abundant resource on earth, however water scarcity affects more than 40% of people worldwide. Access to safe drinking a basic human right and United Nations Sustainable Development Goal (SDG) 6. Globally, waterborne diseases such as cholera are responsible for over two million deaths annually. Cholera major cause ill-health in Africa Uganda. This study aimed determine physicochemical characteristics surface spring endemic communities Uganda order promote...
Introduction In 2010, the World Health Organization released a new cholera vaccine position paper, which recommended use of vaccines in high-risk endemic areas. However, there is paucity data on burden countries. This article reviewed available surveillance from Uganda and assessed sufficiency these to inform country-specific strategies for vaccination. Methods The Ministry conducts guide outbreak control activities. includes reporting number cases based standardized clinical definition plus...
The communities in fishing villages the Great Lakes Region of Africa and particularly Uganda experience recurrent cholera outbreaks that lead to considerable mortality morbidity. We evaluated epidemiology population characteristics better target prevention control interventions contribute its elimination from those communities.
Background For almost 50 years sub-Saharan Africa, including Uganda, has experienced several outbreaks due to Vibrio cholerae. Our aim was determine the genetic relatedness and spread of strains responsible for cholera in Uganda. Methodology/Principal findings Sixty-three V. cholerae isolates collected from Uganda between 2014 2016 were tested using multiplex polymerase chain reaction (PCR), multi-locus variable number tandem repeat analysis (MLVA) whole genome sequencing (WGS). Three...
Inadequate safe water supply and cholera outbreaks are significant contributors to ill health in displaced populations, exacerbating the vulnerability of refugees fleeing conflicts. In November 2021, Nakivale Refugee Settlement faced a outbreak scarcity, putting persons at risk health. This study aimed investigate lessons learned from this incident identify pathways prevent future outbreaks, ultimately safeguarding lives well-being vulnerable populations. A descriptive cross-sectional...
ABSTRACT Background and Aims Despite global efforts to combat tuberculosis (TB), Uganda bears a high burden, with an annual incidence of 200 per 100,000 mortality rate 35 persons. This study investigates TB prevalence, detection rates, associated factors in public health facilities (PHFs) Bududa district. Methods A cross‐sectional employing Mixed Research (MMR) was conducted November 2019 on respondents symptoms suggestive key informants overseeing care district, Uganda. Results Only 18.8%...
Despite advance in science and technology for prevention, detection treatment of cholera, this infectious disease remains a major public health problem many countries sub-Saharan Africa, Uganda inclusive. The aim study was to identify cholera hotspots guide the development roadmap control elimination country.
Cholera burden in Africa remains unknown, often because of weak national surveillance systems. We analyzed data from the African Surveillance Network (www.africhol.org).During June 2011-December 2013, we conducted enhanced seven zones and four outbreak sites Togo, Democratic Republic Congo (DRC), Guinea, Uganda, Mozambique Cote d'Ivoire. All health facilities treating cholera cases were included. incidences calculated using culture-confirmed corrected for lack culture testing usually due to...
Cholera is a major public health problem in the African Great Lakes basin. Two hypotheses might explain this observation namely; lakes are reservoirs of toxigenic V. cholerae O1 and O139 bacteria or cholera outbreaks result repeated pathogen introduction from neighboring communities / countries but facilitate introductions. A prospective study was conducted Uganda between February 2015 January 2016 which 28 selected surface water sources were tested for presence species using rapid test...
Systematic testing for Vibrio cholerae O1 is rare, which means that the world's limited supply of oral cholera vaccines (OCVs) may not be delivered to areas with highest true burden. Here we used a phenomenological model subnational geographic targeting and fine-scale vaccine effects how expanding V. affected impact cost-effectiveness preventive vaccination campaigns across different bacteriological confirmation assumptions in 35 African countries. followed by OCV based on confirmed yielded...
On 12 October 2015, a cholera outbreak involving 65 cases and two deaths was reported in fishing village Hoima District, Western Uganda. Despite initial response by the local health department, persisted. We conducted an investigation to identify source mode of transmission, recommend evidence-led interventions control prevent outbreaks this area. defined suspected case as onset acute watery diarrhoea from 1 2 November 2015 resident Kaiso Village. A confirmed who had Vibrio cholerae isolated...
In July 2009, WHO and partners were notified of a large outbreak unknown illness, including deaths, among African Union (AU) soldiers in Mogadishu. Illnesses characterized by peripheral edema, dyspnea, palpitations, fever. Our objectives to determine the cause outbreak, design recommend control strategies.The illness was defined as acute onset lower limb with chest pain, nausea, vomiting, abdominal or headache. Investigations Nairobi Mogadishu included clinical, epidemiologic, environmental,...
Cholera outbreaks have occurred periodically in Uganda since 1971. The country has experienced intervals of sporadic cases and localized outbreaks, occasionally resulting prolonged widespread epidemics.Cholera surveillance data reported to the Ministry Health from 2007 through 2011 were reviewed determine trends annual incidence case fatality rate. Demographic characteristics cholera analyzed national line list for 2011. Cases by district month report understand geographic distribution...
On 20 June 2015, a cholera outbreak affecting more than 30 people was reported in fishing village, Katwe, Kasese District, south-western Uganda. We investigated this to identify the mode of transmission and recommend control measures. defined suspected case as onset acute watery diarrhoea between 1 15 July 2015 resident Katwe village; confirmed with Vibrio cholerae cultured from stool. For finding, we reviewed medical records actively searched for cases community. In case-control...
Detection, confirmation and monitoring of cholera outbreaks in many developing countries including Uganda is a big challenge due to lack the required resources time test takes. Culture method which takes 24-48 h get feedback requires highly skilled laboratory staff plus other complex standard test. This study evaluated new rapid detection that relies on Crystal VC dipsticks after enrichment with alkaline peptone water (APW) against culture for progress rural setting.We conducted between...
Despite ongoing containment and vaccination efforts, cholera remains prevalent in many countries sub-Saharan Africa. Part of the difficulty containing comes from our lack understanding how it circulates throughout region. To better characterize regional transmission, we generated analyzed 118
Artemisinin-based combination therapy (ACT), the treatment of choice for uncomplicated falciparum malaria, is unaffordable and generally inaccessible in private sector, first port call most malaria across rural Africa. Between August 2007 May 2010, Uganda Ministry Health Medicines Malaria Venture conducted Consortium ACT Private Sector Subsidy (CAPSS) pilot study to test whether access sector could be improved through provision a high level supply chain subsidy.Four intervention districts...