Benon Kwesiga

ORCID: 0000-0003-0400-8635
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About
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Research Areas
  • Viral Infections and Outbreaks Research
  • COVID-19 epidemiological studies
  • Vaccine Coverage and Hesitancy
  • Viral Infections and Vectors
  • Child Nutrition and Water Access
  • Vibrio bacteria research studies
  • Mosquito-borne diseases and control
  • Global Maternal and Child Health
  • Zoonotic diseases and public health
  • Malaria Research and Control
  • Virology and Viral Diseases
  • Pneumonia and Respiratory Infections
  • Data-Driven Disease Surveillance
  • HIV/AIDS Research and Interventions
  • Respiratory viral infections research
  • SARS-CoV-2 and COVID-19 Research
  • Influenza Virus Research Studies
  • Immune responses and vaccinations
  • Adolescent Sexual and Reproductive Health
  • Tuberculosis Research and Epidemiology
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Global Security and Public Health
  • Poisoning and overdose treatments
  • Yersinia bacterium, plague, ectoparasites research
  • Bacillus and Francisella bacterial research

Ministry of Health
2017-2025

National Institute of Public Health
2024

Makerere University
2018-2023

Clarke International University
2023

Uganda Virus Research Institute
2023

African Field Epidemiology Network
2017-2022

Kenya Medical Research Institute
2020

Centers for Disease Control and Prevention
2020

Center for Global Health
2020

Centers for Disease Control and Prevention
2020

Jane Ruth Aceng Alex Riolexus Ario Allan Muruta Issa Makumbi Miriam Nanyunja and 95 more Innocent Komakech Andrew Bakainaga Ambrose Talisuna Collins Mwesigye Allan Mpairwe Jayne Tusiime William Z. Lali Edson Katushabe Felix Ocom Mugagga Kaggwa Bongomin Bodo Hafisa Kasule Joseph Ngobi Mwoga Benjamin Sensasi Edmund Mwebembezi Charles Katureebe Olive Sentumbwe Rita Nalwadda Paul Mbaka Bayo Fatunmbi Lydia Nakiire Mohammed Lamorde Richard Walwema Andrew Kambugu Judith Nanyondo Solome Okware Peter Ahabwe Babigumira Immaculate Nabukenya Joshua Kayiwa Milton M. Wetaka Simon Kyazze Benon Kwesiga Daniel Kadobera Lilian Bulage Carol Nanziri Fred Monje Dativa Maria Aliddeki Vivian Ntono Doreen Gonahasa Sandra Nabatanzi Godfrey Nsereko Anne Nakinsige Eldard Mabumba Bernard Lubwama Musa Sekamatte Michael Kibuule David Muwanguzi Jackson Amone George D. Upenytho Alfred Driwale Morries Seru Fred Sebisubi Harriet Akello Richard Kabanda David K. Mutengeki Tabley Bakyaita Vivian N. Serwanjja Richard Okwi Jude Okiria Emmanuel Ainebyoona Bernard Opar Derrick Mimbe Denis Kyabaggu Chrisostom Ayebazibwe Juliet Sentumbwe Mwanja Moses Deo Birungi Ndumu Josephine Bwogi Stephen Balinandi Luke Nyakarahuka Alex Tumusiime Jackson Kyondo Sophia Mulei Julius J. Lutwama Pontiano Kaleebu Atek Kagirita Susan Nabadda Peter Oumo Robinah Lukwago Julius Kasozi Oleh Masylukov Henry Bosa Kyobe Viorica Berdaga Miriam Lwanga Joe C. Opio David Matseketse James Eyul Martin Olowo Oteba Hasifa Bukirwa Nulu Bulya Ben Masiira Christine Kihembo Chima Ohuabunwo Simon Antara Wilberforce Owembabazi

Abstract Background Since the declaration of 10th Ebola Virus Disease (EVD) outbreak in DRC on 1st Aug 2018, several neighboring countries have been developing and implementing preparedness efforts to prevent EVD cross-border transmission enable timely detection, investigation, response event a confirmed country. We describe Uganda’s experience preparedness. Results On 4 August Uganda Ministry Health (MoH) activated Public Emergency Operations Centre (PHEOC) National Task Force (NTF) for...

10.1186/s12992-020-00548-5 article EN cc-by Globalization and Health 2020-03-19

On April 7, 2024, the Uganda Ministry of Health was notified a measles outbreak in Kakumiro District involving death suspected case. We investigated to determine scope outbreak, assess risk factors for disease transmission, and recommend evidenced-based interventions. defined case as onset fever maculopapular generalized rash with ≥ 1 cough, coryza, or conjunctivitis any resident during February–May 2024. A confirmed laboratory confirmation Immunoglobulin M (IgM) antibody. line-listed cases,...

10.1186/s12982-025-00446-4 article EN cc-by-nc-nd Deleted Journal 2025-02-14

On 6 February 2015, Kampala city authorities alerted the Ugandan Ministry of Health a “strange disease” that killed one person and sickened dozens. We conducted an epidemiologic investigation to identify nature disease, mode transmission, risk factors inform timely effective control measures. defined suspected case as onset fever (≥37.5 °C) for more than 3 days with abdominal pain, headache, negative malaria test or failed anti-malaria treatment, at least 2 following: diarrhea, nausea...

10.1186/s12889-016-4002-0 article EN cc-by BMC Public Health 2017-01-05

Introduction In October 2017, a blood sample from resident of Kween District, Eastern Uganda, tested positive for Marburg virus. Within 24 hour confirmation, rapid outbreak response was initiated. Here, we present results epidemiological and laboratory investigations. Methods A district task force activated consisting specialised teams to conduct case finding, management isolation, contact listing follow up, collection testing, community engagement. An ecological investigation also carried...

10.1371/journal.pntd.0007257 article EN public-domain PLoS neglected tropical diseases 2019-03-18

In May 2015, a cholera outbreak that had lasted 3 months and infected over 100 people was reported in Kasese District, Uganda, where multiple outbreaks occurred previously. We conducted an investigation to identify the mode of transmission guide control measures. defined suspected case as onset acute watery diarrhoea from 1 February 2015 onwards resident. A confirmed with Vibrio cholerae O1 El Tor, serotype Inaba cultured stool sample. reviewed medical records find cases. case-control study...

10.1186/s12889-017-4589-9 article EN cc-by BMC Public Health 2017-07-18

In August 2017, the Uganda Ministry of Health was notified increased cases multidrug-resistant tuberculosis (MDR-TB) in Arua District, during 2017. We investigated to identify scope increase and risk factors for infection, evaluate health facilities' capacity manage MDR-TB, recommend evidence-based control measures.We defined an MDR-TB case-patient as a TB patient attending Regional Referral Hospital (ARRH) 2013-2017 with sputum sample yielding Mycobacterium resistant at least rifampicin...

10.1186/s12879-019-4014-3 article EN cc-by BMC Infectious Diseases 2019-05-07

Abstract Background On March 13, 2020, Uganda instituted COVID-19 symptom screening at its international airport, isolation and SARS-CoV-2 testing for symptomatic persons, mandatory 14-day quarantine of persons traveling through or from high-risk countries. 21, reported first infection in a traveler Dubai. By April 12, 54 cases 1257 contacts were identified. We describe the epidemiological, clinical, transmission characteristics these cases. Methods A confirmed case was laboratory-confirmed...

10.1186/s12992-020-00643-7 article EN cc-by Globalization and Health 2020-11-25

Introduction Crimean-Congo haemorrhagic fever (CCHF) is a tick-borne, zoonotic viral disease that causes symptoms. Despite having eight confirmed outbreaks between 2013 and 2017, all within Uganda’s ‘cattle corridor’, no targeted tick control programs exist in Uganda to prevent disease. During seven-month-period from July 2018-January 2019, the Ministry of Health multiple independent CCHF outbreaks. We investigated identify risk factors recommend interventions future Methods defined case as...

10.1371/journal.pntd.0009213 article EN public-domain PLoS neglected tropical diseases 2021-03-08

Abstract Background Malaria outbreaks are detected by applying the World Health Organization (WHO)-recommended thresholds (the less sensitive 75th percentile or mean + 2 standard deviations [2SD] for medium-to high-transmission areas, and more cumulative sum [C-SUM] method low very low-transmission areas). During 2022, > 50% of districts in Uganda were an epidemic mode according to used, resulting a need restrict national response with highest rates complicated malaria. The three...

10.1186/s12936-024-04838-w article EN cc-by Malaria Journal 2024-01-13

Pneumonia is the second leading cause of hospital admissions and deaths among children <5 years in Uganda. In 2014, Uganda officially rolled out introduction pneumococcal conjugate vaccine (PCV) into routine immunization schedule. However, little known about long-term impact PCV on pneumonia deaths. this study, we described trends spatial distribution mortality Uganda, 2014–2021. We analysed secondary data from District Health Information System version 2 during The proportion cases...

10.1371/journal.pgph.0002980 article EN public-domain PLOS Global Public Health 2025-01-06

<title>Abstract</title> <bold>Background:</bold> On April 7, 2024, the Uganda Ministry of Health was notified a measles outbreak in Kakumiro District involving death suspected case. We investigated to determine scope outbreak, assess risk factors for disease transmission, and recommend evidenced-based interventions. <bold>Methods: </bold>We defined case as onset fever maculopapular generalized rash with ≥1 cough, coryza, or conjunctivitis any resident during February<bold>–</bold>May 2024. A...

10.21203/rs.3.rs-5721498/v1 preprint EN cc-by Research Square (Research Square) 2025-01-08

Background: Coronavirus disease 2019 (COVID-19) vaccination is crucial for healthcare workers (HCWs) and understanding their perspectives vital promoting vaccine uptake in communities.Aim: This study assessed factors influencing COVID-19 among HCWs Kampala, Uganda.Setting: A cross-sectional was done seven high-volume health facilities Kampala.Methods: questionnaire based on the Behavioural Social Drivers Model administered to 200 HCWs. Data were analysed using STATA version 17 identify...

10.4102/jphia.v16i1.720 article EN cc-by Journal of Public Health in Africa 2025-02-28

The coronavirus disease 2019 (COVID-19) pandemic significantly impacted health systems worldwide. This study explored the effects of COVID-19 cascade on programmes in Uganda. conducted in-depth interviews with key informants involved Uganda's national response. A cross-sectional exploratory using qualitative approaches was carried out. purposive sample 30 from Ministry Health (MoH) and implementing partners were interviewed (May 2023 - June 2023). Interviews audio recorded analysed inductive...

10.4102/jphia.v16i1.697 article EN cc-by Journal of Public Health in Africa 2025-03-05

Background On March 7, 2024 the Ministry of Health (MoH) was notified a rising number inmates with suspected conjunctivitis in Luzira prisons Uganda. We investigated this outbreak to determine its cause and extent, identify risk factors recommend evidence-based control measures. Methods four prisons: Kampala Remand Prison (KRP), Murchison Bay (MBP), Upper (LUP) Women (LWP). A case onset redness one or both eyes at least 1 tearing, discharge, grainy sensation, itching, pain, swelling, any...

10.1101/2025.04.04.25325059 preprint EN cc-by 2025-04-08

<title>Abstract</title> Background On June 26, 2024, Ministry of Health was notified a measles outbreak in Moroto District, northeastern Uganda, which had already resulted four deaths. We investigated to assess magnitude the outbreak, identify its source and risk factors, recommend evidence-based control prevention measures. Methods defined suspected case as onset fever maculopapular rash, ≥ 1 cough, coryza, or conjunctivitis resident District from March 15 September 22, 2024. A confirmed...

10.21203/rs.3.rs-6106444/v1 preprint EN Research Square (Research Square) 2025-04-15

On September 20, 2022, the Uganda Ministry of Health declared an outbreak Sudan Virus Disease (SVD). As grew, it became imperative to quickly visualize and analyze chains disease transmission. Determining epidemiological links between cases is critical for control as incorrect linkages may result in missed case detection undetected We describe Health’s experience using Chainchecker, a computer application designed verify transmission chain data. To use line list documenting details...

10.1371/journal.pgph.0004352 article EN public-domain PLOS Global Public Health 2025-04-21

Abstract Background Jimsonweed ( Datura stramonium ) contains toxic alkaloids that cause gastrointestinal and central nervous system symptoms when ingested. This can be lethal at high doses. The plant may grow together with leguminous crops, mixing them during harvesting. On 13 March 2019, more than 200 case-patients were admitted to multiple health centres for acute neurologic symptoms. We investigated determine the magnitude of outbreak recommended evidence-based control prevention...

10.1186/s12889-022-12854-1 article EN cc-by BMC Public Health 2022-03-30

Kampala city slums, with one million dwellers living in poor sanitary conditions, frequently experience cholera outbreaks. On 6 January 2019, Rubaga Division notified the Uganda Ministry of Health a suspected outbreak Sembule village. We investigated to identify source and mode transmission, recommended evidence-based interventions.We defined case as onset profuse, painless, acute watery diarrhoea City resident (≥ 2 years) from 28 December 2018 11 February 2019. A confirmed was Vibrio...

10.1186/s12879-021-07011-9 article EN cc-by BMC Infectious Diseases 2021-12-01

Disease surveillance provides vital data for disease prevention and control programs. Incomplete untimely are common challenges in planning, monitoring, evaluation of health sector performance, service delivery. Weekly sent from facilities using mobile tracking (mTRAC) program, synchronized into the District Health Information Software version 2 (DHIS2). The then merged district, regional, national level datasets. We described completeness timeliness weekly reporting on epidemic prone...

10.1186/s12889-023-15534-w article EN cc-by BMC Public Health 2023-04-04

In Uganda, sepsis is the third-leading cause of neonatal deaths. Neonatal can be early-onset (EOS), which occurs ≤ 7 days postpartum and usually vertically transmitted from mother to newborn during intrapartum period, or late-onset (LOS), occurring 8-28 largely acquired hospital environment community. We described trends spatial distribution in 2016-2020.We conducted a descriptive incidence study using routinely-reported surveillance data on in-patient District Health Information System...

10.1186/s12884-023-06037-y article EN cc-by BMC Pregnancy and Childbirth 2023-11-04

On 20 June 2015, a cholera outbreak affecting more than 30 people was reported in fishing village, Katwe, Kasese District, south-western Uganda. We investigated this to identify the mode of transmission and recommend control measures. defined suspected case as onset acute watery diarrhoea between 1 15 July 2015 resident Katwe village; confirmed with Vibrio cholerae cultured from stool. For finding, we reviewed medical records actively searched for cases community. In case-control...

10.1371/journal.pone.0198431 article EN cc-by PLoS ONE 2018-06-27
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