- Diabetic Foot Ulcer Assessment and Management
- Wound Healing and Treatments
- Pressure Ulcer Prevention and Management
- Diagnosis and Treatment of Venous Diseases
- Peripheral Artery Disease Management
- Surgical Sutures and Adhesives
- Surgical site infection prevention
- Balance, Gait, and Falls Prevention
- Venous Thromboembolism Diagnosis and Management
- Skin Diseases and Diabetes
- Foot and Ankle Surgery
- Lower Extremity Biomechanics and Pathologies
- Stroke Rehabilitation and Recovery
- Reconstructive Surgery and Microvascular Techniques
- Pain Mechanisms and Treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Diabetes Management and Research
- Angiogenesis and VEGF in Cancer
- Psoriasis: Treatment and Pathogenesis
- Cerebral Palsy and Movement Disorders
- Diabetes Treatment and Management
- Neurological Disorders and Treatments
- Inflammatory Myopathies and Dermatomyositis
- Muscle and Compartmental Disorders
- Vitamin C and Antioxidants Research
City Of Hope National Medical Center
2025
Rosalind Franklin University of Medicine and Science
2015-2024
City of Hope
2024
University of St. Augustine for Health Sciences
2023
VA Maryland Health Care System
2023
Cedars-Sinai Medical Center
2022
Cedars-Sinai Smidt Heart Institute
2022
Cedarville University
2020
Howell Laboratories (United States)
2017
Advocate Lutheran General Hospital
2006-2015
The purpose of this study was to evaluate the effectiveness a removable cast walker (RCW) and an "instant" total contact (iTCC) in healing neuropathic diabetic foot ulcerations.We randomly assigned 50 patients with University Texas grade 1A ulcerations into one two off-loading treatment groups: RCW or same wrapped cohesive bandage so could not easily remove device. Subjects were evaluated weekly for 12 weeks until wound healing.An intent-to-treat analysis showed that higher proportion had...
Pressure mitigation is crucial for the healing of plantar diabetic foot ulcers. We therefore discuss characteristics and considerations associated with use offloading devices.A ulcer management survey was sent to clinics in all 50 states District Columbia 2005. A total 901 geographically diverse centers responded. The recorded information regarding usage frequency assessment treatment ulcers each center.Of 895 respondents who treat ulcers, shoe modifications (41.2%, P < 0.03) were most...
Introduction: Currently, diagnosis of patients with postural instability relies on a rudimentary clinical examination. This article suggests an innovative, portable, and cost-effective prototype to evaluate balance control objectively. Methods: The proposed system uses low-cost, microelectromechanical sensor, body-worn sensors (BalanSens™) measure the motion ankle hip joints in three dimensions. We also integrated resulting data into two-link biomechanical model human body for estimating...
There are currently over 80 biomaterials derived from autologous, allogeneic, synthetic and xenogeneic sources, or a combination of any all these types materials, available for soft-tissue coverage to effect wound closure. Often generically referred as cellular and/or tissue-based products (CTPs), they manufactured under various trade names marketed variety indications.
There is a significant and troubling link between diabetes (DM) falls in the elderly. Individuals with DM are prone to fall for reasons such as decreased sensorimotor function, musculoskeletal/neuromuscular deficits, foot body pain, pharmacological complications, specialty (offloading) footwear devices. Additionally, there some concern that patients have more severe problems than non-DM individuals. Fractures, poorer rehabilitation, increased number of all concerns. Fortunately, efforts...
The aim of our case-control study was to compare selected psychological and social characteristics between diabetic patients with without the DF (controls). Methods . 104 48 were included into study. Both groups compared in terms psychosocial characteristics. Results Compared controls, had a significantly worse quality life area health standard living as shown by lower physical domain (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mn...
Hemorrhagic cystitis (HC) is an early complication after hematopoietic cell transplant (HCT) with post-transplant cyclophosphamide (PTCy). Hyperhydration can reduce HC, but may lead to fluid overload (FO), which has been associated higher non-relapse mortality (NRM) HCT. The objectives of this study were grade FO between days 3 and 8 based on weight gain, diuretic therapy, FO-related organ dysfunction analyze the impact subsequently overall survival (OS) patients undergoing HCT PTCy-based...
Abstract The purpose of this study was to evaluate outcomes persons with UT grade 2A neuropathic diabetic foot wounds treated an acellular matrix. Data were abstracted for 17 consecutive patients diabetes – 76·5% males, aged 61·5 ± 8·5 years a mean glycated haemoglobin 9·2 2·2% presenting care at large, multidisciplinary wound centre. All received surgical debridement their and placed on therapy consisting single application matrix graft (GraftJacket™; Wright Medical Technologies, Arlington,...
Abstract The purpose of this project was to evaluate associations increasing diabetic foot surgery stage with postoperative outcome. This project, designed as a retrospective cohort model, conducted at three large, urban referral‐based clinics. investigators abstracted medical records from 180 patients diabetes, 76·1% male, aged 57·8 ± 11·2 years, falling equally into four classes previously reported classification system. These included class 1 (elective), 2 (prophylactic), 3 (curative) and...
Abstract The objective of this study was to examine the safety cenplacel (PDA‐002) in patients with peripheral arterial disease (PAD) and a diabetic foot ulcer (DFU). Cenplacel is mesenchymal‐like cell population derived from full‐term human placenta. This phase 1, dose‐escalation investigated chronic DFUs (Wagner grade 1 or 2) PAD [ankle‐brachial index (ABI) >0·5 ≤0·9], enrolled sequentially into each four dose cohorts (3 × 10 6 , 30 100 cells; administered intramuscularly on days 8...
Abstract Clinical trials of potential new therapies for diabetic foot ulcers rarely enroll patients whose wounds extend to muscle, fascia, or bone with clinical and radiographic evidence underlying osteomyelitis. An open‐label, multicenter trial cryopreserved human umbilical cord (TTAX01) was undertaken in 32 subjects presenting such complex a mean duration 6.1 ± 9.0 (range: 0.2–47.1) months wound area at screening 3.8 2.9 1.0–9.6) cm 2 . Aggressive surgical debridement baseline resulted 17...
Abstract The use of antiseptics in wound care is often controversial and there definitely a need for non toxic, highly disinfective agent. This study assessed the efficacy neutral pH superoxidised aqueous solution (NpHSS) infection control, odour reduction surrounding skin tissue damage on infected diabetic foot ulcerations. From November 2003 to March 2004, 45 patients with type 2 diabetes were randomised into single‐blind clinical trial comparing NpHSS (intervention group; n = 21) versus...