- Research on Leishmaniasis Studies
- Veterinary Oncology Research
- Virus-based gene therapy research
- Leptospirosis research and findings
- Parasitic Infections and Diagnostics
- Animal Virus Infections Studies
- Rabies epidemiology and control
- Viral gastroenteritis research and epidemiology
- Vector-Borne Animal Diseases
- Virology and Viral Diseases
- Herpesvirus Infections and Treatments
- Vector-borne infectious diseases
- Trypanosoma species research and implications
- SARS-CoV-2 and COVID-19 Research
- Infectious Diseases and Mycology
- Animal Disease Management and Epidemiology
- T-cell and Retrovirus Studies
- Reproductive Physiology in Livestock
- Corneal Surgery and Treatments
- Toxoplasma gondii Research Studies
- Syphilis Diagnosis and Treatment
- Microbial infections and disease research
- Veterinary Medicine and Surgery
- Renal and related cancers
- Toxin Mechanisms and Immunotoxins
Universidade Estadual Paulista (Unesp)
2014-2024
Fundação de Estudo e Pesquisa em Medicina Veterinária e Zootecnia
2014
University of Cincinnati
2012
Michigan State University
2012
Universidade de São Paulo
2000-2011
Fundação Faculdade de Medicina
2011
Universidade Estadual de Londrina
2005
Cornell University
2003
Visceral leishmaniasis in Brazil is caused by Leishmania (Leishmania) chagasi and the dog its most important reservoir. The clinical features dogs include loss of weight, lymphadenopathy, renal failure, skin lesions, fever, hypergammaglobulinemia, hepatosplenomegaly, anemia, and, rarely, neurological symptoms. Most infected animals develop active disease, characterized high anti-leishmania antibody titers depressed lymphoproliferative ability. Antibody production not primarily for protection...
Since December 2019, the world has been experiencing COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and we now face emergence of several variants. We aimed to assess differences between wild-type (Wt) (Wuhan) strain P.1 (Gamma) Delta variants using infected K18-hACE2 mice. The clinical manifestations, behavior, virus load, pulmonary capacity, histopathological alterations were analyzed. P.1-infected mice showed weight loss more manifestations than...
A rapid indirect enzyme-linked immunosorbent assay (ELISA) was developed for measuring antibodies against Leishmania chagasi using total antigen from lysed promastigotes. Fifty symptomatic mixed breed dogs a region of high incidence visceral leishmaniasis in Brazil were examined. The results showed that the positive animals, diagnosed by cytological examination, ELISA protein system (mean optical density ± SD / 2.078 0.631) detected more than anti-IgG 1.008 0.437), while negative both...
Poult enteritis complex has been incriminated as a major cause of loss among turkey poults in other countries. We have observed this Brazil, associated with diarrhoea, weight gain and, commonly, high mortality. In study, we used the reverse transcriptase polymerase chain reaction (RT-PCR) to detect coronavirus (TCoV) sick 30 120 days age from particular producer region Brazil. The RT-PCR was applied extracts intestine tissue suspensions, and respective intestinal contents, bursa Fabrícius,...
This experiment studied congenital transmission in sheep experimentally infected with oocysts of Toxoplasma gondii and reinfected at one three stages pregnancy. Twenty ewes were T. strain ME49 (day 0). After the infection became chronic (IFAT≤512), allocated rams for coverage. diagnosis pregnancy, these into four experimental groups (n = 5): I-reinfected on 40th day gestation (DG); II-reinfected DG 80; III-reinfected 120; IV-saline solution 120 (not reinfected). Five (IFAT<64) kept as...
Summary Objectives: To evaluate bone healing in an experimental radial ostectomy dogs treated with autologous platelet-rich plasma (PRP), through histological, densitometric, radiographic studies, as well expression of growth factors the gap. Methods: Twenty-one were randomly divided into either a control or PRP group. All underwent unilateral radius to generate gap 2.0 mm, that was stabilized external skeletal fixation. The filled left empty control. and densitometric studies performed...
A survey of Turkey Coronavirus (TCoV) and Astrovirus (TAstV-2) prevalence was carried out from February to December during 2006 year in semiarid region Brazil, a turkey producer area, localized South Eastern Brazil. To asses the risk factor related clinical material, climatic condition type RT-PCR applied, cloacal swabs (CS), faeces, sera, bursa Fabricius (BF), thymus (TH) spleen (SP) ileum-caeca were collected 30-day-old poults suffering enteritis episode characterized as poult mortality...
COVID-19 causes more severe and frequently fatal disease in patients with pre-existing comorbidities such as hypertension heart disease. SARS-CoV-2 virus enters host cells through the angiotensin-converting enzyme 2 (ACE2), which is fundamental maintaining arterial pressure renin-angiotensin system (RAS). Hypertensive commonly use medications inhibitors (ACEi), can modulate expression of ACE2 and, therefore, potentially impact susceptibility severity infection. Here we assessed whether...
Canine transmissible venereal tumour (CTVT) is a neoplasm transmitted among healthy dogs by direct contact with injured skin and/or mucous tissue. This study aimed to identify the TP53 gene, messenger RNA (mRNA) as well expression of p53, Bcl‐2 and p63 proteins in histological sections 13 CTVT samples at different stages evolution. The situ hybridization (ISH) reverse transcriptase polymerase chain reaction (RT‐PCR) assays were used, which showed DNA homologous its respective mRNA 92.3%...