A5062744056- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Toxin Mechanisms and Immunotoxins
- Vector-borne infectious diseases
- Parasites and Host Interactions
- COVID-19 epidemiological studies
- COVID-19 Pandemic Impacts
- Leptospirosis research and findings
- vaccines and immunoinformatics approaches
- Viral Infections and Vectors
- Insect and Pesticide Research
- COVID-19 impact on air quality
- Mosquito-borne diseases and control
- Vector-Borne Animal Diseases
- Zoonotic diseases and public health
- SARS-CoV-2 and COVID-19 Research
- Immune Response and Inflammation
- Viral gastroenteritis research and epidemiology
- Biochemical and Molecular Research
- T-cell and B-cell Immunology
- Monoclonal and Polyclonal Antibodies Research
- Synthesis and Biological Evaluation
- Viral Infections and Immunology Research
- T-cell and Retrovirus Studies
- Heart rate and cardiovascular health
Universidade Federal de Ouro Preto
2016-2025
Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais
2014-2024
Instituto Politécnico de Leiria
2024
Universidade Federal de Minas Gerais
2001-2023
National Council for Scientific and Technological Development
2021
Fundação Oswaldo Cruz
2006-2017
Universidade Federal de Santa Catarina
2008
National Training Service
2008
Brazil is the only country endemic for zoonotic visceral leishmaniasis (ZVL) that regularly conducts epidemiologic and prophylactic control programs involve treatment of human cases, insect vector control, removal seropositive infected dogs. This report reviews 60 studies reporting data on efficacy these recommended tools concludes in 1) eradication disease Minas Gerais was achieved by concomitant use three methods, 2) although seropositivity an immunofluorescent assay not completely related...
Background Various factors contribute to the urbanization of visceral leishmaniasis (VL), including difficulties implementing control measures relating domestic reservoir. The aim this study was determine prevalence canine in an urban endemic area Brazil and associated with Leishmania infantum infection among seronegative PCR-positive dogs. Methodology A cross-sectional conducted Belo Horizonte, Minas Gerais, Brazil. Blood samples were collected from 1,443 Serology carried out by using two...
Abstract Leishmaniasis is a highly diverse group of diseases caused by kinetoplastid the genus Leishmania . These parasites are taxonomically diverse, with human pathogenic species separated into two subgenera according to their development site inside alimentary tract sand fly insect vector. The disease encompasses variable spectrum clinical manifestations tegumentary or visceral symptoms. Among causative in Brazil, (Leishmania) amazonensis an important etiological agent cutaneous...
Polymerase chain reaction (PCR) and its variations represent highly sensitive specific methods for Leishmania DNA detection subsequent canine visceral leishmaniasis (CVL) diagnosis. The aim of this work was to compare three different molecular diagnosis techniques (conventional PCR [cPCR], seminested [snPCR], quantitative [qPCR]) in samples skin spleen from 60 seropositive dogs by immunofluorescence antibody test enzyme-linked immunosorbent assay. Parasitological analysis conducted culture...
The techniques used for diagnosis of canine visceral leishmaniasis (CVL) in Brazil ELISA and IFAT have been extensively questioned because the accuracy these tests. A recent change protocol excluded included Dual-Path Platform (DPP). We evaluated prevalence incidence rates Leishmania spp. before after protocol. In addition, based on our results, we propose a new alternative that is less expensive screening confirmation CVL. Plasma samples were obtained from serobank dogs cross-sectional...
Background Visceral leishmaniasis is the most severe form of leishmaniasis. Worldwide, approximately 20% zoonotic human visceral caused by Leishmania infantum, also known as chagasi in Latin America. Current diagnostic methods are not accurate enough to identify Leishmania-infected animals and may compromise effectiveness disease control. Therefore, we aimed produce test two recombinant multiepitope proteins a means improve increase accuracy diagnosis canine (CVL). Methodology/Principal...
The performances of ELISA assays with different antigen preparations, such as Leishmania amazonensis or L. chagasi lysates and the recombinant antigens rK-39 rK-26, were compared using sera eluates from dried blood collected on filter paper to detect anti-Leishmania antibodies in dogs a visceral leishmaniasis-endemic area Brazil. Of 115 IFAT-reactive at 1:40 titre, 106 (92.2%) positive parasitological exams (skin and/or spleen). These animals healthy (n = 25), negative for IFAT titre exams....
Summary Canine visceral leishmaniasis (CVL) manifests itself as a broad clinical spectrum ranging from asymptomatic infection to patent severe disease. Despite relevant findings suggesting changes on lymphocytes subsets regarding the CVL forms, it still remains be elucidated whether distinct phenotypic profile would correlated with degree of tissue parasite density. Herein, we have assessed correlation between status well impact bone marrow density peripheral blood leucocytes in 40 Brazilian...