- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Management of metastatic bone disease
- Medical Imaging and Analysis
- Bone Tumor Diagnosis and Treatments
- Tumors and Oncological Cases
- Pelvic and Acetabular Injuries
- Sarcoma Diagnosis and Treatment
- Histiocytic Disorders and Treatments
- Cancer Diagnosis and Treatment
- Soft tissue tumor case studies
- Hematological disorders and diagnostics
- Toxoplasma gondii Research Studies
- Neurogenetic and Muscular Disorders Research
- Neurological disorders and treatments
- Soft tissue tumors and treatment
- Bone and Joint Diseases
- Neuroinflammation and Neurodegeneration Mechanisms
- Mesenchymal stem cell research
- Cerebral Palsy and Movement Disorders
- Cervical and Thoracic Myelopathy
- Vascular Procedures and Complications
- Viral-associated cancers and disorders
- Venous Thromboembolism Diagnosis and Management
- Osteomyelitis and Bone Disorders Research
D.Y. Patil University
2021-2023
Dr. D. Y. Patil Medical College, Hospital and Research Centre
2021-2023
King Edward Memorial Hospital and Seth G.S. Medical College
2018-2019
College of Medicine & JNM Hospital
2019
Allen Institute for Brain Science
2019
Summary Seeking new insights into the homeostasis, modulation and plasticity of cortical synaptic networks, we have analyzed results from a single-cell RNA-seq study 22,439 mouse neocortical neurons. Our analysis exposes transcriptomic evidence for dozens molecularly distinct neuropeptidergic modulatory networks that directly interconnect all This begins with discovery transcripts one or more neuropeptide precursor (NPP) neuropeptide-selective G-protein-coupled receptor (NP-GPCR) genes are...
Study Design Cadaveric, observational study. Purpose Atlantoaxial instability (AAI) is characterized by excessive movement at the C1–C2 junction between atlas and axis. An anterior surgical approach to expose upper cervical spine for internal fixation bone grafting has been developed fix AAI. Currently, no anatomic information exists on transarticular atlantoaxial screw or plate C1 C2 in Indian population. The objective of this study assess landmarks vertebrae: entry point, trajectory,...
Context: Fusion of lumbar spine is one the standards care for various pathologies such as canal stenosis and spondylolisthesis. Transforaminal interbody fusion (TLIF) achieves necessary goals but with greater muscular trauma due to denervation loss muscle mass which may result in poor short-term outcomes. Minimally invasive-TLIF (MIS-TLIF) overcomes these shortcomings by preserving splitting dilating muscles. Aims: The minimally invasive procedures are reduce iatrogenic injury, postoperative...
Pseudoaneurysms of arteries are not uncommon complications vessel handling during surgery. Early identification and management is important to prevent disastrous such as rupture thrombosis.We describe a case 28-year-old male who developed pseudoaneurysm the radial artery after being operated by plating for mid-shaft radius fracture. He presented 2 weeks surgery with swelling over forearm which was confirmed be computed tomography angiography. It treated surgical excision end-to-end...
A 70 years old lady presented to us with history of a fall 3 months prior. She had suffered type 2 odontoid fracture atlantoaxial dislocation, that was not reducible by traction. symptoms neck pain inability hold the upright. The patient subsequently planned for anterior release and reduction dislocation posterior stabilization in same sitting. treated cervical skeletal traction immobilized. However, she developed occipital sore during period mobilized brace after which myelopathic gait...
To determine the entry for dorsal pedicular screw in relation to notch present at junction of base lateral margin superior articular process with border transverse spine. The advantage this technique is a constant and easily identifiable point which does not involve partial resection inferior facet, thus maintaining stability well defined sagittal angles decreasing incidence medial pedicle violation.The study was carried out using ten cadavers (four male six female). Spinal column dissected...
Vertebral hemangiomas although benign vascular lesions few of these may be ag-gressive causing osseous, extra-osseous and/or epidural expansions with recurrence rate as low 3%. It should considered one the important differentials while dealing lytic in dorsal spine compressive myelopathy.A 16-year-old female came an acute history paraparesis bladder in-volvement. She was diagnosed vertebral hemangioma D9 for which she underwent surgical decompression and fixation. At present, had a sensory...
Abstract Purpose: Cement distribution in spinal stabilization with fenestrated screws is unpredictable patients osteoporosis. The objective of our study was an assessment cement while using and to establish association between the Dual Emission X-ray Absorptiometry (DEXA) scan T scores. Materials Methods: Osteoporotic who underwent by a single surgeon minimum follow-up one year were included. (four zones comprising vertebral body pedicle), pattern (concentrated or scattered) leakage assessed...
Leiomyomas are benign epithelial tumors with a female preponderance usually in the uterus, gastro-intestinal tract and skin. They well-capsulated no mitotic activity little pleomorphism. Primary leiomyoma upper cervical spine region is rare occurrence of these lesions young immunocompetent males extremely rare.A 15-year-old male had swelling over nape neck for 4 years slight difficulty movements few months. Asymptomatic back be developed painless at on right side initially size pea which...
Langerhans cell histiocytosis (LCH) is a common disease in the pediatric population with peak incidence between 5 and 10 years of age. Eosinophilic granuloma (EG) accounts for less than 1% all primary bone tumors primarily affecting skull, pelvis, ribs metaphyses long bones benign localized form LCH. It extremely rare adults, more so spine, predilection thoracic spine lumbar cervical region. A 35-year-old gentleman presented transitional mid back pain two months radiating to right flank...
Abstract Purpose : We retrospectively analysed a cohort of patients treated at our Centre with bone marrow concentrated (BMC) injection for aneurysmal cyst (ABC) the spine, in order to propose this treatment as valid alternative management ABCs. Methods Fourteen (6 male, 8 female) were between June 2014 December 2019 BMC ABC spine. The mean age was 17.85 years. follow up 37.4 months (range 12- 60 months). dimension and degree ossification measured by Computed Tomography (CT) scans before...
We retrospectively analyzed a cohort of patients treated at our Centre with bone marrow concentrated (BMC) injection for aneurysmal cyst (ABC) the spine, in order to propose this treatment as valid alternative management ABCs.Fourteen (6 male, 8 female) were between June 2014 December 2019 BMC ABC spine. The mean age was 15.5 years. follow up 37.4 months (range 12-60 months). dimension and degree ossification measured by Computed Tomography (CT) scans before during follow-up visits.Six...