A5039017654- Adolescent and Pediatric Healthcare
- Childhood Cancer Survivors' Quality of Life
- Diabetes Management and Research
- Pancreatic function and diabetes
- Occupational Therapy Practice and Research
- Diabetes and associated disorders
- Assistive Technology in Communication and Mobility
- Diabetes Treatment and Management
- Occupational Health and Safety in Workplaces
- HIV Research and Treatment
- Child and Adolescent Psychosocial and Emotional Development
- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- Pharmaceutical studies and practices
- Acute Lymphoblastic Leukemia research
- Bipolar Disorder and Treatment
- Medication Adherence and Compliance
- Child Nutrition and Feeding Issues
- Urban Transport and Accessibility
- Ethics and Legal Issues in Pediatric Healthcare
- Eosinophilic Esophagitis
- Family and Disability Support Research
- Asthma and respiratory diseases
- Housing, Finance, and Neoliberalism
- Digital Mental Health Interventions
Children's Hospital of Richmond at VCU
2018-2023
Virginia Commonwealth University
2020-2023
Boston College
2021
Levine Cancer Institute
2021
Harvard University
2016-2017
Boston Children's Hospital
2017
Cincinnati Children's Hospital Medical Center
2009-2016
University of Cincinnati
2009-2016
University of Cincinnati Medical Center
2013
Michigan Medicine
2013
OBJECTIVE The primary aim of the study was to investigate relationship among executive functioning, diabetes treatment adherence, and glycemic control. RESEARCH DESIGN AND METHODS Two hundred thirty-five children with type 1 their caregivers were administered Diabetes Self-Management Profile assess adherence. Executive functioning measured using Behavior Rating Inventory Functioning control based on A1C. RESULTS Structural equation modeling indicated that a model in which adherence mediated...
To test models of unidirectional and bidirectional change between treatment adherence glycemic control in youth with type 1 diabetes.We conducted a 2-year longitudinal, multisite study 225 diabetes recruited at the cusp adolescence (aged 9-11 years) to describe mutual influences as measured by HbA(1c) blood glucose monitoring frequency (BGMF) during transition adolescence.HbA(1c) increased from 8.2 8.6% (P < 0.001) BGMF decreased 4.9 4.5 checks per day 0.02) period. Changes slope predicted...
Intrapartum intravenous zidovudine (ZDV) prophylaxis is a long-standing component of prevention mother-to-child transmission (MTCT) human immunodeficiency virus (HIV) in high-resource countries. In some recent guidelines, ZDV no longer systematically recommended for mothers receiving combination antiretroviral therapy (cART) with low viral load. We evaluated the impact according to load and obstetrical conditions. All HIV-1-infected women delivering between 1 January 1997 31 December 2010...
The purpose of this study was to determine the intrapatient (within same patient) variability tacrolimus in adherent patients. Daily trough levels were obtained at home using dried blood spot technology kidney and liver transplant recipients. Patients randomized receive 3 formulations tacrolimus, each for two 1-week periods. Adherence monitored by patient diary, pill counts, use Medication Event Monitoring System (MEMS). Variability quantified as coefficient variation (CV). Comparison CV...
Objectives The primary aims of the study were to: (a) describe trajectories adherence to daily inhaled corticosteroid (ICS) medication for a year in economically disadvantaged, African-American youth with asthma based on growth curve modeling; and (b) test relationship treatment symptom control, quick-relief medication, healthcare utilization. Methods This prospective measured ICS using electronic monitoring 92 children adolescents moderate severe 9–12 months assessed clinical outcomes,...
Objective-To identify trajectories of glycemic control over a period three years in pediatric sample youth diagnosed with type 1 diabetes transitioning to adolescence.A second aim was examine set modifiable individual and family-level baseline predictors group membership.Methods-This multisite, prospective study included 239 children adolescents (ages 9-11 at baseline) their caregivers.Glycemic based on hemoglobin A1c (HbA1c) collected six month intervals years.Predictors membership global...
Objective To investigate the relation of changes in executive functioning to diabetes self-management a 2-year prospective study sample youth aged 9–11 years at baseline (n = 239) with type 1 and their maternal caregivers. Research Design Methods Youth caregivers completed Diabetes Self-Management Profile (DSMP) baseline, 12 months, 24 months. Maternal Behavioral Rating Inventory Executive Functioning (BRIEF) same time points assess global functioning, domains behavioral regulation...
High rates of asthma treatment nonadherence have been reported, particularly in economically disadvantaged African American youth. The relationship between adherence to combined medication and outcomes has potential clinical significance but is not well understood. Using electronic monitoring, we describe the pattern daily corticosteroid (fluticasone) leukotriene receptor antagonist (montelukast) over course 1 year a population youth with moderate severe asthma. On average, montelukast was...
Adolescence poses a number of special challenges for youth and their families managing the Type 1 diabetes medical regimen. Little is known on how family factors management regimen change over course early adolescence predict adherence to during this developmental period.Youth with (n = 239) maternal caregivers completed measures diabetes-specific autonomy support, diabetes-related conflict, responsibility, blood glucose monitoring frequency (BGMF) at 4 timepoints 3-year period.Autonomy...
We enrolled 64 patients age 12 to 22 years with a diagnosis of poorly controlled persistent asthma in 6-month longitudinal crossover study. During the 3 intervention months, participants created personalized text messages be sent their phones. Adherence was objectively monitored participants. The adolescent gave high ratings on acceptability messaging system. Asthma control improved from baseline month 1 regardless whether teens were texting or group. While group, quality life and worry...
This study described the prospective relationship between pharmacological and behavioral measures of 6-mercaptopurine (6MP) medication adherence in a multisite cohort pediatric patients diagnosed with cancer ( N = 139).Pharmacological (i.e., metabolite concentrations) assessed 6MP intake. Behavioral (e.g., electronic monitoring) patterns over time.Three profiles were identified across 15 months: one group demonstrated low levels both metabolites (40.8%) consistent nonadherence and/or...
To examine the relationship of mother-father informant discrepancies regarding diabetes management to diabetes-specific family conflict and glycemic control.One hundred thirty-six mothers fathers youth with Type 1 reported on youth's management, conflict, amount paternal involvement in care. Glycosylated hemoglobin A1c (HbA1c) was used measure control.As hypothesized, were positively associated frequency conflict. Contrary hypotheses, predicted poorer control for less involved only.Results...
Rohan JM, Delamater A, Pendley JS, Dolan L, Reeves G, Drotar D. Identification of self-management patterns in pediatric type 1 diabetes using cluster analysis. Objectives: This study identified three distinct groups for a sample 239 youth (9–11 years) with and their maternal paternal caregivers, assessed relationship to glycemic control (HbA1c). Methods: Youth caregivers were administered the profile (DSMP) assess self-management. Glycemic was based on hemoglobin A1c. Results: Two-step...
Objective To describe patterns of treatment adherence to early maintenance phase therapy for acute lymphoblastic leukemia (ALL) and lymphoma (LBL). Methods Using an objective observational method (electronic monitoring), was examined 139 patients aged 7–19 years diagnosed with ALL or LBL across 6 centers. Results The mean percentage 86.2%. Adherence rates declined over the 1-month follow-up 83%. 3 linear trajectories 6-mercaptopurine were identified: (1) exemplary (n = 99): Averaging nearly...
This research examined whether individual and family-level factors during the transition from late childhood to early adolescence protected individuals an increased risk of poor glycemic control across time, which is a predictor future diabetes-related complications (i.e., health resilience).This longitudinal, multisite study included 239 patients with type 1 diabetes their caregivers. Glycemic was based on hemoglobin A1c. Individual included: demographic variables, youth behavioral...
The present study assessed the relationship between resilience, adherence, and transition readiness in adolescents/young adults with chronic illness. Participants included 50 patients (Mean age, Mage = 17.3 ± 2.1 years) diagnosed an oncology disorder (n 7; 12.1%), hematology 5; 8.6%), nephrology 31; 53.4%), or rheumatology 12.1%). Patients were administered questionnaires assessing resilience (Conner-Davidson Resilience Scale 25-item questionnaire, CD-RISC-25), (Self-Management Transition to...
Objective To document current clinical practices for medical regimen adherence assessment and intervention in the field of pediatric psychology. Methods 113 members Society Pediatric Psychology completed an anonymous online survey that assessed use assessments interventions practice, barriers facilitators to their use, preferred resources obtaining information on interventions. Results Respondents reported using a range strategies, some which are evidence-based. Barriers implementing these...
This paper presents case examples that document the preliminary clinical utility of using electronic monitoring (EM) feedback to tailor empirically validated adherence-promoting interventions, delivered in standard practice. Challenges utilizing EM practice as well future directions are also discussed. Two adolescents referred for behavioral adherence promotion intervention described. Each youth was provided a MEMS® bottle and one oral medication chosen jointly by therapist, family, medical...
This report describes an intervention to promote medication adherence and treat comorbid psychological symptoms in a 17 year-old female with Fanconi Anemia. The patient presented typical rate estimated at 25% self-reported of depressed mood anxiety.Our comprehensive treatment approach integrated electronic monitoring (EM), emerging strategy for promotion, motivational interviewing (MI) within evidence-based cognitive-behavioral therapy (CBT) framework. We used EM data assess track adherence....
Objective To document trajectories of paternal involvement in diabetes management and examine bidirectional associations with outcomes across early adolescence. Methods 3-year prospective assessment involvement, self-management, glycemic control among 136 youth (age 9–12 at baseline) their mothers fathers. Results Unconditional growth curves demonstrated decreasing amount (maternal report: F(1,128) = 14.79; F(1,111) 12.95, ps < 0.01) level contribution F(1,131) 23.6, p .01) involvement....