A5101681563- Neuroscience and Neuropharmacology Research
- Ovarian function and disorders
- Saffron Plant Research Studies
- Fatty Acid Research and Health
- Cholesterol and Lipid Metabolism
- Gut microbiota and health
- Metabolism and Genetic Disorders
- Adipose Tissue and Metabolism
- Anesthesia and Neurotoxicity Research
- Diet and metabolism studies
- Metal complexes synthesis and properties
- Nuts composition and effects
- Endometriosis Research and Treatment
- Bone health and osteoporosis research
- Neuroinflammation and Neurodegeneration Mechanisms
- Molecular Sensors and Ion Detection
- Inflammatory Bowel Disease
- Chemotherapy-induced organ toxicity mitigation
- Bee Products Chemical Analysis
- Pharmacogenetics and Drug Metabolism
- Pharmacological Effects and Toxicity Studies
- Lung Cancer Treatments and Mutations
- Synthesis and biological activity
- Phytochemical and Pharmacological Studies
- Neurological Disorders and Treatments
Arak University of Medical Sciences
2023
Tehran University of Medical Sciences
2008-2021
Bushehr University of Medical Sciences
2020
Shahid Beheshti University of Medical Sciences
2019
Iran University of Medical Sciences
2019
Type 2 diabetes (T2D) is accompanied by elevated inflammation, oxidative stress, hyperlipidemia and hyperglycemia which all contribute to cardiovascular disease pathogenesis. Saffron as a complementary medicine source of antioxidants could play role in alleviating its complications. The aim this study was determine the effects saffron supplementation an adjunct therapy T2D.This randomized controlled trial included 80 T2D patients with mean age 54.1 years. Participants were randomly assigned...
Polycystic ovary syndrome (PCOS) continues to be one of the most complex reproductive and endocrine disorder among women age. Recent reports have identified close interaction Vitamin D deficiency oxidative stress (OS) in exacerbating pathophysiology PCOS. This current study aims at assessing combine effect MitoQ10 D3 on dehydroepiandrosterone (DHEA) induced Following successful induction PCOS using DHEA, mice were organized into five groups (n = 8) namely: Negative Control (NC), Vehicle...
Abstract Inflammatory bowel disease (IBD) is a chronic recurrent of the digestive tract with an unknown etiology. The aim this study was to examine possible protective effects N-acetylcysteine (NAC) in mouse model IBD by measuring specific biomarkers colon cells. Colitis induced administration dextran sodium sulfate (DSS) drinking water (3%) for 7 days. Three doses NAC (106, 160, and 240 mg/kg) were given after induction colitis (4 days post DSS) 4 gavage. Lipid peroxides (LP), total...
Emergence agitation (EA) is an important clinical problem that occurs during the initial period of recovery from anesthesia. This study aimed to determine effects ketamine and lidocaine administered on level, postoperative pain, hemodynamic changes in adults after rhinoplasty.Totally 72 patients scheduled undergo elective rhinoplasty were enrolled this prospective study. Patients randomly divided into three groups including control group (n = 24), 24). Twenty minutes before surgery...
Epilepsy is recognized as a chronic neurologic disease. Increasing evidence has addressed the antioxidant and anti-inflammatory roles of olive leaf extract (OLE) in neurodegenerative diseases. So, current study aimed to investigate neuroprotective OLE epilepsy.Forty rats were divided into 4 groups including control group, sham kainic acid (KA) KA + group. (4 μg/rat) was injected intrahippocampal, (300 mg/kg) orally administrated for weeks. Animals sacrificed, their hippocampi isolated. KA-...
Background: With 1.36 million new cases in worldwide each year, breast cancer (BC) is the most common malignancy female. Among numerous chemotherapy drugs which are widely used for therapy, platinum compounds persuasive ones although challenges remain with clinical use of them due to their side effects as well intrinsic and acquired resistance. In attempt combat drug resistance, reduce cytotoxic or find particular forms cancer, over years, thousands other (Pt) i.e. carboplatin oxaliplatin...
Abstract Background and Aims Epileptic seizures occur as a consequence of sudden imbalance between the stimuli inhibitors within network cortical neurons in favor stimulus. One drugs that induce epilepsy is pilocarpine. Systemic injection pilocarpine affects on muscarinic receptors. Increasing evidence has addressed implication KN‐93 by blocking Ca 2+ /calmodulin‐dependent protein kinase II (CaMKII), suppressing oxidative stress inflammation, also reducing neuron decay. So, we aimed to...
Epilepsy is a resulting from sudden bursts of electrical energy in the brain and these discharges produce seizures which vary one person to another frequency form [1].If signal goes through all brain, may shake over, fall lose consciousness [2].Epilepsy (also known as 'seizure disorder') chronic neurological disorder characterized by recurring [3].A seizure occurs when message delivery system becomes unbalanced there not enough gamma amino butyric acid (GABA), occur because receiving neurons...
Introduction: Familial adenomatous polyposis (FAP) is a rare and hereditary disease in which multiple precancerous polyps develop the patient's colon. caused by mutations APC gene (5q21). According to new research, addition nuclear disorders, mitochondrial functional disorders are also one of essential carcinogenic factors promising target for cancer treatment. The aim this study was investigate nucleotide changes ATPase6 MT-CYB genes patients with FAP. Methods: In study, 9 Iranian families...