A5108650968- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Adipokines, Inflammation, and Metabolic Diseases
- Sirtuins and Resveratrol in Medicine
- Liver Disease Diagnosis and Treatment
- Adipose Tissue and Metabolism
- Genomics, phytochemicals, and oxidative stress
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Autophagy in Disease and Therapy
- Ovarian function and disorders
- Diet, Metabolism, and Disease
- Gout, Hyperuricemia, Uric Acid
- Animal Genetics and Reproduction
- Advances in Cucurbitaceae Research
- Patient Satisfaction in Healthcare
- Stress Responses and Cortisol
- Nerve injury and regeneration
- NF-κB Signaling Pathways
- Exercise and Physiological Responses
- Calcium signaling and nucleotide metabolism
- Inflammasome and immune disorders
- Extracellular vesicles in disease
Tehran University of Medical Sciences
2012-2025
Kashan University of Medical Sciences
2024
University of Tehran
2022
Mazandaran University of Medical Sciences
2015
Iran Meteorological Organization
2013
Hasheminejad Kidney Center
2012
Shahid Beheshti University of Medical Sciences
2012
Ecole Mohammadia d'Ingénieurs
2011
Abstract Resveratrol was reported to inhibit inflammatory responses; however, the role of this polyphenol in obesity-induced skeletal muscle inflammation remains unknown. Mice fed a high fat diet (HFD) were treated with resveratrol for 16 weeks. treatment decreased macrophage infiltration into HFD-fed mice. also led polarization macrophages M2 direction, as well decreasing expression number M1 pro-inflammatory cytokines [tumor necrosis factor α (TNF-α), interleukin 1 β (IL-1β) and 6 (IL-6)]....
Abstract Background This study was designed to examine the effect of resveratrol on mitochondrial biogenesis, oxidative stress (OS), and assisted reproductive technology (ART) outcomes in individuals with polycystic ovary syndrome (PCOS). Methods Fifty-six patients PCOS were randomly assigned receive 800 mg/day or placebo for 60 days. The primary outcome OS follicular fluid (FF). secondary involved assessing gene protein expression related DNA (mtDNA) copy number, adenosine triphosphate...
The quality of life patients with end-stage renal disease is an important indicator burden. To achieve a better life, some medical treatment might be replaced by other approaches. aim this study was to compare the renal-transplanted and hemodialysis in Iran. Two hundred 200 transplantation were recruited from 5 major hospitals patients' support society Tehran, data collected using Persian versions Ferrans Powers Quality Life Index-Dialysis Transplantation Version. quality-of-life mean scores...
Summary The gene Nrf2 (nuclear factor‐erythroid 2‐related factor 2) is the most important regulator of cellular antioxidant system and its dysregulation has a role in etiology nonalcoholic fatty liver disease (NAFLD). aim this study was to investigate association between targeted miRNAs (miR‐27a, miR‐142‐5p, miR‐153, miR‐128) with lipid accumulation vitro vivo models NAFLD. We used two expression genes assessed by real‐time PCR protein level evaluated using western blot. To potential NAFLD,...
Polycystic ovary syndrome (PCOS) continues to be one of the most complex reproductive and endocrine disorder among women age. Recent reports have identified close interaction Vitamin D deficiency oxidative stress (OS) in exacerbating pathophysiology PCOS. This current study aims at assessing combine effect MitoQ10 D3 on dehydroepiandrosterone (DHEA) induced Following successful induction PCOS using DHEA, mice were organized into five groups (n = 8) namely: Negative Control (NC), Vehicle...
Abstract Background Cryostorage of spermatogonial stem cells (SSCs) is an appropriate procedure for long-term storage SSCs fertility preservation. However, it causes damage to cellular structures through overproduction ROS and oxidative stress. In this study, we examined the protective effect melatonin as a potent antioxidant in basic freezing medium establish optimal cryopreservation method SSCs. Methods were obtained from testes neonatal male mice aged 3–6 days. Then, 100 μM was added...
Central nervous system (CNS) lesions can repeatedly be de-and remyelinated during demyelinating diseases such as multiple sclerosis (MS). Here, we designed an intermittent demyelination model by 0.3 % Cuprizone feeding in C57/BL6 mice followed two weeks recovery. Histochemical staining of luxol fast blue (LFB) was used for study remyelination, detection glial and endothelial cells performed immunohistochemistry the following antibodies: anti Olig2 oligodendrocyte progenitor cells, APC mature...
Background: In the last decade H9N2 avian influenza viruses had caused outbreaks in poultry many parts of world. This subtype could infect other animals such as human and pig. Avian virus has acquired receptor binding characteristics typical humans strains, increasing potential for reassortment both pig respiratory tracts. indicates that A/H9N2 would be a threat to population. Objectives: The aim this was indentify presence among different high risk occupational groups, Tehran Qazvin...
We intend to describe the imaging findings of sudden cardiac arrest occurring during computed tomographic (CT) examination and also impending cardiogenic shock in 4 patients. Despite rare reports acute or shortly after CT scan, features are quite characteristic. Familiarity with these patients is essential for accurate interpretation images, immediate initiation resuscitation, as well informing clinical physician conditions.
Animal model studies suggest that change in the members of suppressor cytokine signaling (SOCS) family (mainly SOCS1 and SOCS3) is linked to pathogenesis obesity-related metabolic disorders. Moreover, epigenetic modification involved transcriptional regulation SOCS gene family. Here, we aimed evaluate mRNA expression as well promoter methylation SOCS3 subcutaneous adipose tissue (SAT) from obese women compared normal-weight subjects. We also intend identify possible association transcript...
In reproductive biology, testicular organoids can be used to treat infertility and study development spermatogonial stem cells (SSCs) differentiation. Generating organoid from primary is challenging. this study, were created using human evaluated the apoptotic gene expression hormone secretion profiles of organoids.
MicroRNAs have been shown to regulate lipogenesis in liver. The aim of the present study was investigate whether effects resveratrol (RSV) on are associated with changes expression two miRNAs (miR-107 and miR-10b) that lipogenic pathways. 30 wild type C57BL/6j male mice were randomly fed three diets: a standard chow diet (ND), high fat (HFD, 60% fat) supplemented 0.4% RSV (HFD-RSV) for 16 weeks. HepG2 cells treated glucose (33 mM) (20 µM) 24 h. genes measured by real-time PCR. Triglyceride...