A5068030467- Molecular Biology Techniques and Applications
- Hedgehog Signaling Pathway Studies
- Esophageal and GI Pathology
- Parathyroid Disorders and Treatments
- Gastric Cancer Management and Outcomes
- RNA Research and Splicing
- Colorectal Cancer Surgical Treatments
- Epigenetics and DNA Methylation
- Dysphagia Assessment and Management
- Retinal Imaging and Analysis
- Neurological Disease Mechanisms and Treatments
- Cancer-related molecular mechanisms research
- Esophageal Cancer Research and Treatment
- Fungal and yeast genetics research
- RNA modifications and cancer
- Biomarkers in Disease Mechanisms
- Kruppel-like factors research
- Bioinformatics and Genomic Networks
- Retinal Diseases and Treatments
- Gastroesophageal reflux and treatments
- Gene expression and cancer classification
- Colorectal and Anal Carcinomas
- Galectins and Cancer Biology
- Genetic Syndromes and Imprinting
China Medical University
2023-2024
First Hospital of China Medical University
2023-2024
Peking University
2023
Peking University Third Hospital
2023
Ministry of Education of the People's Republic of China
2023
First Affiliated Hospital of Xinjiang Medical University
2022
Xinjiang Medical University
2022
Fudan University
2009-2020
State Key Laboratory of Genetic Engineering
2020
Zhongshan Hospital
2014
Objective The aim of this study was to evaluate the safety and efficacy endoscopic balloon dilatation ( EBD ) for benign esophageal strictures after ESD early neoplasms. Methods Data 335 patients who were treated with neoplasms from October 2006 August 2012 retrospectively reviewed. characteristics underwent post‐ESD stricture analyzed. Results A total 117 procedures performed in 29 stricture. mean number sessions 4.0 (range 1–15) no complications occurred during procedures. median follow‐up...
BackgroundTranscriptional regulators are seminal players in the onset and progression of prostate cancer. However, clarification their underlying regulatory circuits mechanisms demands considerable effort.MethodsIntegrated analyses were performed on genomic, transcriptomic, clinicopathological profiles primary cancer transcription factor-binding profiles, which included estimating factor activity, identifying factors prognostic values, discovering cis- trans-regulations by long noncoding...
ABSTRACT Background In patients with chronic kidney disease (CKD), vascular calcification (VC) is common and associated a higher risk of all-cause mortality. Shh, one ligand for Hedgehog (Hh) signaling, participates in osteogenesis several cardiovascular diseases. However, it remains unclear whether Shh implicated the development VC. Methods Inorganic phosphorus 2.6 mM was used to induce smooth muscle cells (VSMCs) calcification. Mice were fed adenine diet supplement 1.2% Results decreased...
To improve the understanding of esophageal leakage after peroral endoscopic myotomy (POEM).From August 2010 to April 2013, patients with postoperative were identified from database cases achalasia who had undergone POEM and their medical records reviewed.Three (0.4%, 3/679) developed POEM. All three non-severe chest or upper abdominal pain within 3 days procedure. Infections observed, computed tomography scans showed pleural effusion in all patients. Pneumonia occurred two Esophageal was...
Age-related macular degeneration (AMD) is a chronic and progressive disease, which can also lead to serious visual loss. In our research, we aim efficiently identify biomarkers relevant for AMD diagnosis. We collected the gene expression data of retinal segmented epithelium (RPE) retina tissues GSE29801 GSE135092 performed differential analysis. The differentially expressed genes (DEGs) related RPE in two sets were identified enriched by intersection A PPI network was constructed genes, top...
<p>Sequencing technology has undergone major breakthroughs over time and become indispensable in biological medical research. Advances protocols analysis algorithms allow the of small sample inputs, enabling characterization complex networks that govern processes physiology pathology, driving development precision medicine targeted therapy. In this review, we comprehensively summarize low-input sequencing technologies include methods for profiling genome, epigenome, transcriptome,...
Objective The aim of this study is to evaluate the accuracy EUS in rectal cancer restaging after neoadjuvant therapy. Methods staging was performed therapy 61 patients who were diagnosed as having local advanced cancer. All underwent subsequent surgical resection and complete pathologic staging. Results Compared with pathological staging, total post-therapy T-staging 59. 0% （36/61）. T-overstaging rate 36. 1% （22/61） understaging 4. 9% （3/61）. Accuracy N-staging 68.9% （42/61） , N-overstaging...