Neurofibromatosis 1 (NF1) represents a cluster of clinical features based on the National Institute Health(NIH) diagnostic criteria. It is multi-systemic disease with progressive characterized by variable expression. NF1 associated an increased risk malignancies including breast cancer. Presented was 56 year old woman painless lump in right past 15 months. Clinical evaluation revealed and advanced Histologic invasive ductal carcinoma she offered modified radical mastectomy. Due to...

Plasma cell mastitis (PCM) is a chronic inflammatory disease of the breast. It benign entity mainly found in nonpregnant and nonlactating women. PCM presents with symptoms inflammation, breast erythema, masses, indurations. We herein describe 26-year-old woman 2-year history right swelling 1-year left during pregnancy lactation. She was clinically diagnosed bilateral cancer, but biopsy specimen revealed PCM. During lactation, can present as lesions. Early presentation diagnosis are crucial...

Schwannomas are benign neoplasm's arising from Schwann cells. Malignant change is rare.A 42-yearold man presented with a 6-year history of recurrent right sided multinodular scalp lesion.Surgery revealed multiple ovoid masses in lesion. Histology schwannoma.Schwannoma may present as lesions multilobulated lesion and should be considered differential diagnosis.

Aims: To determine the prevalence of cancer in rest Cross River State not covered by population-based registry which is limited to capital city Calabar.
 Study Design: Descriptive retrospective study involving a trend analysis cancers from Calabar registry. Cancers incident Pathology and Haematology departments University Teaching hospital are included study.
 Place Duration Study: hospital. Data was assessed between April May 2019.
 Methodology: An institution-based...

Aim: The aim of this study is to determine the incidence prostate cancer in men living Calabar- Nigeria, which has not been determined up till now. Study Design: A trend analysis cases Calabar between 1

Mucoepidermoid carcinoma is the most frequently encountered salivary gland usually presenting as small, painless, asymptomatic mass. Presented a 54-year-old male security personnel with 5-year history of giant locally advanced, nodular, and ulcerated left sided facial tumour diagnosed mucoepidermoid on histology. can attain grotesque dimension management challenges. We present this case, we have not MEC large conclude that it should be considered differential diagnosis tumours.

Neurofibrosarcoma is a malignancy that occurs more frequently in patients with neurofibromatosis- 1 (NF- 1) and rarely may arise independently. This presentation of 3 consecutive histologic diagnosis neurofibrosarcoma who presented to the University Calabar Teaching Hospital, from 2011-2013. Two were associated NF-1 decade younger than one without NF-1. Late poor follow up notable underlying factors. Long term NF -1 for early adequate treatment will improve outcome.

Objective: To report a rare occurrence of giant, solitary, cystic, intramuscular plexiform neurofibroma in the thigh.Case Report: A 45-year-old architect presented with 5-year history painless, progressively enlarging soft tissue mass right thigh, which was diagnosed on histology as cystic after excision biopsy. Conclusion:A should be considered differentials solitary thigh even absence usual manifestations Neurofibromatosis.

Eosinophilic oesophagitis (EoE) is a chronic immune and antigen-mediated disease characterized by symptoms related to oesophageal dysfunction histologically, marked eosinophilic infiltrate in the mucosa. It prevalent developed countries considered rare developing countries. There an interplay of allergic genetic factors aetiology EoE. This report EoE 15-year-old female adolescent Nigeria who presented University Calabar Teaching Hospital with recurrent vomiting, abdominal pain, weight loss,...

Extra gastrointestinal stromal tumour(EGIST) is rare and regarded as tumour(GIST) that originates outside of the tract. They originate from other intraabdominal tissues such omentum, mesentery peritoneum. The cell origin interstitial Cajal(ICC), a pacemaker controls peristalsis tumor characterized by expression KIT(CD117) transmembrane tyrosine kinase receptor. Here, 49-year-old female who presented with 6 month history abdominal pain, progressive swelling presence an upper mass. She had...

Non-acquired immunodeficiency syndrome-defining cancers (NADCs) are malignancies in persons living with human virus (PLWHIV) and not primarily due to the host’s immunodeficiency. There is renewed clinical interest long-term morbidities PLWHIV as well that occur this population. We herein describe a 36-year-old woman 2-year history of an anal wound right breast mass. She had been diagnosed HIV infection prior development these lesions. Clinical laboratory evaluations led diagnoses cancers....

Intussusception is defined as the invagination of a proximal segment bowel into adjoining or distal segment. In most adults with intussusception, there demonstrable lead point definite pathologic abnormality. The clinical features intussusception include chronic intermittent abdominal pain, nausea and vomiting, constipation, palpable mass. present case report describes 62-year-old woman 2-week history pain 9-day vomiting. Clinical, imaging, histologic evaluations revealed jejunojejunal...

Umbilical endometriosis or Villar's nodule is defined as the presence of endometrial tissue within umbilicus and represent 0.5%-1% cases ectopia. It classified primary secondary based on surgical history. The important symptoms that characterize umbilical were cyclical pain a palpable mass may be associated with bleeding. These features have temporal association catamenia. Presented 30 year old woman clinical suggested in past 5 years. was confirmed by histology coexisted uterine fibroid. In...

Uterine leiomyomas are common benign gynecological tumors due to the overgrowth of uterine smooth muscle. Pedunculated leiomyoma occurs when mass is in continuity with uterus a stalk and may grow either within cavity or outside mimic ovarian neoplasms intraabdominal tumors. Presented 28-year-old woman progressive abdominal swelling past 9 months seen at surgical outpatient our facility. Preoperative CT suggested diagnosis an intrabdominal cystic. She had laparotomy was offered myomectomies...

The concurrent occurrence of plasma cell mastitis(PCM) and breast cancer is rare. Plasma a chronic inflammatory disease. Metastatic cancer(MBC) that has spread to another part the body commonly bones, lungs, liver or brain. Presented 28 year old woman who was seen at emergency department with difficulty in breathing abdominal swelling one month two weeks duration respectively. In previous year, she diagnosed bilateral PCM but declined therapy. Clinical, imaging laboratory evaluation revealed...

Lipomas are benign tumors of mesodermal origin composed mature adipocytes. They classified into superficial and deep types located in the subcutaneous subfascial locations respectively. The is further subdivided 2 subtypes intermuscular intramuscular. Presented was a 63 year old woman with right sided swelling buttock past 7 months. Clinical, imaging histologic evaluation resulted definitive diagnosis giant intramuscular lipoma gluteus. lesion well circumscribed defined pseudo capsule an...

Abstract Pediatric-type follicular lymphoma (PFL) is a rare, nonaggressive, slow-growing (indolent), non-Hodgkin that typically seen in males as localized disease with excellent outcomes. It largely different from (FL). Few published studies on PFL are case series developed nations. We report patient advanced PFL, 14-year-old female 5-year history of neck swellings, abdominal distension for month, and pericardial effusion, among others. The swellings waxed waned; involved all the peripheral...

The disparity in age of diagnosis and genetic testing breast cancer among African women is a major cause concern. common inherited genes like gene 1 (BRCA1), 2 (BRCA2) Tumour protein 53 (TP53 or p53) as well increase collagen deposition the stroma predispose to early cancer. aim this study was establish immunohistochemical expressions patterns BRCA1, BRCA2, p53 proteins changes females with onset cancers University Calabar Teaching Hospital. Data on tumours occurrences 96 were obtained from...

Ultrasound is operator-dependent, and its value efficacy in fetal morphology assessment a low-resource setting poorly understood. We assessed the of ultrasound Nigerian setting.We surveyed performed across five facilities followed-up each fetus to ascertain outcome. Fetuses were second trimester (18th-22nd weeks) using International Society Obstetrics Gynecology (ISUOG) guideline. Clinical surgical reports used as references assess diagnostic livebirths, autopsy confirm anomalies terminated...

Background: Cutaneous metastasis is valuable though with infrequent occurrence in clinical practice. It of esteem value diagnosis as well treatment cancer due to the ease accessibility for examination and biopsy. Case Series: This a presentation 5 consecutive patients histologic cutaneous metastatic malignancies at University Calabar Teaching Hospital, (UCTH), Calabar, Nigeria from 2010 2013. They were studied an attempt evaluate significance nodules/disease tropical setting. was compared...

Background: Virchow in 1860 described liposarcoma which arise from fat cells. It is a common soft tissue sarcoma found commonly the limbs and retroperitoneum.Objectives: This study an attempt to highlight biographic indices, pattern, challenges of management outcomes tropical setting proffer solutions for improved outcome.Methods: Patients who presented University Calabar Teaching Hospital 2000-2014 with histologic diagnosis were studied. was compared total malignancy seen during same...