- Pesticide and Herbicide Environmental Studies
- Weed Control and Herbicide Applications
- Allelopathy and phytotoxic interactions
- Plant Physiology and Cultivation Studies
- Photosynthetic Processes and Mechanisms
- Horticultural and Viticultural Research
- Ecology and Conservation Studies
- Plant Stress Responses and Tolerance
- Pesticide Residue Analysis and Safety
- Plant tissue culture and regeneration
- Synthesis and Biological Evaluation
- Porphyrin Metabolism and Disorders
- Synthesis and biological activity
- Analytical Chemistry and Chromatography
- Chemical Synthesis and Analysis
- Neuropeptides and Animal Physiology
- Phenothiazines and Benzothiazines Synthesis and Activities
- Energy, Environment, Agriculture Analysis
- Porphyrin and Phthalocyanine Chemistry
- Synthesis and Reactions of Organic Compounds
- Chromatography in Natural Products
- Plant Molecular Biology Research
- GABA and Rice Research
- Peroxisome Proliferator-Activated Receptors
- Plant and animal studies
Osaka University
2025
Saitama Cancer Center
2024
Kawasaki Medical School
2019-2023
Juntendo University Hospital
2023
University of Tsukuba
2011-2022
Kansai Medical University
2015-2020
Takara (United States)
2019
Ube (Japan)
2014-2018
Yamaguchi University
2014-2017
Toyohashi University of Technology
2010-2017
Inflammatory stimuli and lipid peroxidation activate nuclear factor kappa B (NF-κB) upregulate proinflammatory cytokines chemokines. The present study evaluated the relationship between pathological liver injury, endotoxemia, peroxidation, NF-κB activation imbalance pro- anti-inflammatory cytokines. Rats (5 per group) were fed ethanol a diet containing saturated fat, palm oil, corn or fish oil by intragastric infusion. Dextrose isocalorically replaced in control rats. Pathological analysis...
Several commercial and experimental herbicides such as p -nitrodiphenyl ethers, oxadiazoles, cyclic imides inhibit protoporphyrinogen IX oxidase (Protox), the enzyme that converts to protoporphyrin (Proto). This leads uncontrolled autooxidation of substrate results in accumulation Proto. Blockage porphyrin pathway at this site inhibits synthesis both chlorophylls heme. Heme is a feedback regulator pathway. Thus, inhibition Protox also deregulates pathway, causing increased carbon flow...
Summary Californian populations of Echinochloa phyllopogon have evolved multiple‐herbicide resistance ( MHR ), posing a threat to rice production in California. Previously, we identified two CYP 81A cytochrome P450 genes whose overexpression is associated with acetolactate synthase ALS ) inhibitors from chemical groups. Resistance mechanisms other herbicides remain unknown. We analyzed the sensitivity an line acetyl‐CoA carboxylase ACC ase) three groups, followed by analysis herbicide...
Abstract Xyloglucan endotransglucosylases/hydrolases (XTHs) that mediate cleavage and rejoining of the β (1-4)-xyloglucans primary cell wall are considered to play an important role in construction restructuring xyloglucan cross-links. A novel rice (Oryza sativa) XTH-related gene, OsXTH8, was cloned characterized after being identified by cDNA microarray analysis gibberellin-induced changes gene expression seedlings. OsXTH8 a single copy gene; its full-length 1,298 bp encoding predicted...
With a leaf disc assay, 11 species were tested for effects of the herbicide acifluorfen on porphyrin accumulation in darkness and subsequent electrolyte leakage photobleaching chlorophyll after exposure to light. Protoporphyrin IX (Proto IX) was only that substantially increased by any species. However, there wide range amount Proto caused 0.1 millimolar between Within species, reduced effect older tissues. Therefore, direct quantitative comparisons are difficult. Nevertheless, when data...
Recent indoor environmental design is requested to create comfortable and safety space in addition the maximizing energy conservation performance buildings. In this point of view, it important enhance prediction accuracy quality stage. Commercial Computational Fluid Dynamics (CFD) software practically applied recent years but CFD simulation depends on understanding for fundamentals fluid dynamics setting appropriate boundary numerical conditions as well. The series study aimed provide with...
Abstract Purpose Fire victims often inhale hydrogen cyanide (HCN) gas in addition to carbon monoxide. This study aimed investigate the current prevalence of HCN inhalation among fire and assess contribution as a toxic factor fire-related deaths. Methods The included 29 cases deaths, where autopsies were conducted at Department Legal Medicine, Osaka University, from April 2014 March 2020. No resuscitation was performed before death confirmed blood samples obtained both left right cardiac...
N-acylated or D enantiomer peptide derivatives based on the sequence RRWQWRMKK in lactoferricin B demonstrated antimicrobial activities greater than those of against bacteria and fungi. The most potent peptide, conjugated with an 11-carbon-chain acyl group, showed two to eight times lower MIC B.
Walker–Warburg syndrome (WWS) is a congenital muscular dystrophy associated with neuronal migration disorder and structural eye abnormalities. The mutations in the <i>O</i>-mannosyltransferase 1 gene (<i>POMT1</i>) were identified recently 20% of patients WWS. authors report on patient WWS novel <i>POMT1</i> mutation. Their expressed α-dystroglycan (α-DG) core protein, but fully glycosylated α-DG antibody epitopes absent, loss laminin-binding activity.
Abstract Purpose: N 1,N12-diacetylspermine (DiAcSpm) in the urine of colorectal and breast cancer patients was examined to establish its usefulness as a novel diagnostic tool for detecting these cancers at clinically early stages. Experimental Design: Urine samples from 248 colon 83 well 51 with benign gastrointestinal diseases treated Tokyo Metropolitan Komagome Hospital during period August 1999 January 2004 were collected. DiAcSpm analyzed by ELISA sensitivity malignant conditions...
A multiresidue method for pesticides that enables quantitative, sequential analysis of a large number vegetable and fruit samples by gas chromatography/mass spectrometry has been developed. First, 89 important target compounds were selected monitoring, then the appropriate internal standards these pesticides, 14 stable isotopically labeled (surrogates), used. The sample was extracted with acetonitrile, extract cleaned up salting-out step followed redissolution in ethyl acetate. Coextractives...
Particle trajectories are numerically followed in the presence of space‐ and time‐varying electric magnetic fields that obtained by previous two‐dimensional magnetohydrodynamic (MHD) simulation X type reconnection process (Hayashi Sato, 1978). Two conclusions notable. First, those particles encounter a slow shock layer associated with suffer an abrupt large orbit modification whereby they gain energy roughly one order larger than corresponding to Alfven speed, i.e., several electron volts...