- Cancer Cells and Metastasis
- RNA Research and Splicing
- Developmental Biology and Gene Regulation
- Immunotherapy and Immune Responses
- Monoclonal and Polyclonal Antibodies Research
- Wnt/β-catenin signaling in development and cancer
- Phytase and its Applications
- Cancer-related Molecular Pathways
- T-cell and B-cell Immunology
- Moringa oleifera research and applications
- Glycosylation and Glycoproteins Research
- Immune Cell Function and Interaction
- Viral Infectious Diseases and Gene Expression in Insects
- Genomics and Chromatin Dynamics
Yunnan Agricultural University
2016-2021
Tea Research Institute
2016-2018
Abstract Use of paclitaxel as monotherapy or in combination with other therapeutic agents is a widely employed front‐line chemotherapeutic strategy for cervical cancer. However, previous reports have shown that approximately 70% the patients cancer develop resistance to paclitaxel. Epithelial–mesenchymal transition (EMT) contributes occurrence chemoresistance several types cancer, including Identification critical signaling pathway regulates EMT process may provide novel avoiding delaying...
Abstract BACKGROUND Moringa leaf is licensed as a new food ingredient and rich in nutrients. However, owing to its high cellulose content, the nutrients are difficult digest absorb, which limits product development application of leaf. RESULTS Four bacterial strains – Trichoderma reesei CICC 2626, Bacillus pumilus 10440, subtilis subsp . 21934, sp 21942 were chosen ferment with powder. The results solid fermentation liquid show that solid‐state using 10440 1:60 ratio powder produced greatest...
Abstract Notch signaling is a highly conserved pathway existed in multicellular organisms. It plays roles normal human body development, cancer initiation, progression and metastasis. The negative regulatory region (NRR) critical for signaling, cleavage at the S2 site NRR ultimately leads to activation of signaling. To study function NRR1, we expressed recombinant NRR1 (rhNRR1) domain Escherichia coli . After purification, rhNRR1 was obtained with approximately 94% purity according SDS‐PAGE...