A5065073742- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Sesquiterpenes and Asteraceae Studies
- Plant Ecology and Taxonomy Studies
- Plant chemical constituents analysis
- Berberine and alkaloids research
- Botanical Research and Chemistry
- Chemical synthesis and alkaloids
- Plant biochemistry and biosynthesis
- Allelopathy and phytotoxic interactions
- Biological Activity of Diterpenoids and Biflavonoids
- Medicinal Plant Research
- Plant-based Medicinal Research
- Alkaloids: synthesis and pharmacology
- Phytochemicals and Antioxidant Activities
- Traditional Chinese Medicine Analysis
- Insect Pest Control Strategies
- Toxin Mechanisms and Immunotoxins
- Heavy Metals in Plants
- Bioactive Compounds and Antitumor Agents
- Ethnobotanical and Medicinal Plants Studies
- Steroid Chemistry and Biochemistry
- Drug-Induced Hepatotoxicity and Protection
- Plant tissue culture and regeneration
Anadolu University
2011-2023
Eskişehir City Hospital
2010-2023
Hacettepe University
2019
Usak University
2005
Inonu University
2005
Gazi University
2005
Pharmac
1991
Essential oils of peppermint Mentha piperita L. (Lamiaceae), which are used in flavors, fragrances, and pharmaceuticals, were investigated for their antimicrobial properties against 21 human plant pathogenic microorganisms. The bioactivity the menthol menthone was compared using combination vitro techniques such as microdilution, agar diffusion, bioautography. It shown that all screened strongly inhibited microorganisms, whereas pathogens only moderately inhibited. Chemical compositions...
Water-distilled essential oils from herbal parts of Micromeria cristata (Hampe) Griseb. subsp. phrygia P. H. Davis (Endemic) (Lamiaceae) collected three different localities were analyzed by GC-MS. The major component characterized in the was borneol (27-39%). Other main components determined as camphor (9-15%), caryophyllene oxide (4-6%), and trans-verbenol (4-6%) oils. Enantiomeric distributions on a fused silica Lipodex-E capillary column using multidimensional GC-MS system. both...
Abstract Essential oils from 23 species of plants comprising 14 genera and 4 plant families were obtained by Clevenger‐type water distillation. The major compounds in these essential identified with GC‐MS their insecticidal activity against adult turnip aphids, Lipaphis pseudobrassicae (Davis), tested dosage‐mortality bioassays. We examined mortality only for viviparous adults because sizeable aphid populations on crucifer (Brassicaceae) hosts are largely produced wingless, parthenogenic...
Abstract Terpene derivatives converted by microbial biotransformation constitute an important resource for natural pharmaceutical, fragrance, and aroma substances. In the present study, monoterpene α ‐phellandrene was biotransformed 16 different strains of microorganisms (bacteria, fungi, yeasts). The transformation metabolites were initially screened TLC GC/MS, then further characterized NMR spectroscopic techniques. Among six characterized, 6‐hydroxypiperitone, epoxide, cis‐p...
In this study, the polar extract of Arum italicum Miller tubers was fractionated by 'biological activity guided fractionation' method.MCF-7 (human breast adenocarcinoma) and A549 (non-small lung cancer) cancer cell lines were used to screen cytotoxic activity.Possible antiproliferative apoptotic effects each subfraction evaluated in vitro.As a result, E2 against while E3 E6 showed good activities both lines.These three subfractions comparable with positive control.The chemical composition...
ABSTRACT Water-distilled essential oils of Origanum majorana L. collected from two localities in Turkey were analyzed by GC and GC/MS. Carvacrol (78.27–79.46%) was found to be the major component both oils.
A new, 4-(2-propenyl)-phenyl angelate (1) and four known phenylpropanoids (2 - 5), were isolated from Pimpinella isaurica, a species endemic in Turkey. One new sesquiterpene, 1-methyl-4-(5-methyl-1-methylenehex-4-enyl)-7-oxabicyclo[4.1.0]heptane (6) was obtained P. aurea two (7, 8), corymbosa. The structure elucidation of the compounds 1 6 achieved by combination one- (1H, 13C) two-dimensional NMR techniques (G-DQF-COSY, G-HMQC, G-HMBC) LC-ESI-FTMS. Compounds 1, 2, 4, 6, 7, 8 have been...
Abstract The essential oils from 20 samples of wild and cultivated collections Satureja hortensis L. were investigated by GC GC/MS. forms contained carvacrol (42–63%) as the major constituent. Thymol (29–43%) was main component in S. hortensis.
ABSTRACT Essential oil composition of four subspecies Origanum vulgare L. (Labiatae, Sect. Majorana); subsp. hirtum (Link) Ietswaart, gracile (C. Koch) and viride (Boiss.) Hayek growing wild in Turkey have been examined by GC GC/MS analysis. More than 80 constituents were identified the samples subspecies. O. was rich carvacrol (70.47%), while contained β-caryophyllene (17.54%) germacrene D (12.75%) as dominant constituents. The major components terpinen-4-ol (16.82%) (15.87%), + (20.94%) (17.80%).
A new 'phenylpropanoid', 4-(3-methyloxiran-2-yl)phenyl 2-methylbutanoate (1), a trinorsesquiterpene, 4-(6-methylbicyclo[4.1.0]hept-2-en-7-yl)butan-2-one (2), and eight known compounds (3-10) were isolated from the essential oils of several Pimpinella species growing in Turkey. The structures determined by 1D- 2D-NMR analyses. absolute configuration 1 was established via comparison its optical rotation with that 'epoxypseudoisoeugenyl 2-methylbutyrate' (11), which chemical degradation an...
Several plants and plant-derived pure compounds, designated as phytoestrogens, have been reported to cause estrogenic effects. They used for alleviation of menopausal symptoms, prevention osteoporosis, heart disease cancer. There is an increased interest in studying phytoestrogens such isoflavones lignans their use replacements synthetic estrogens. In this study, the activity essential oils eleven Pimpinella species compounds isolated from these were evaluated using yeast estrogen screen...
The essential oils obtained by water distillation from aerial parts of Achillea schischkinii Sosn. and aleppica DC. subsp. were analyzed gas chromatography chromatography/mass spectrometry. 1,8-Cineole (32.5 26.1%, respectively) was the main component in both oils. oil A. also found to be rich bisabolol its derivates. When tested for their antimicrobial, antiinflammatory, antinociceptive activities, showed significant antinociceptive, moderate antimicrobial activities.
Pimpinella essential oils and isolated compounds were screened for their inhibitory activity against NF-kappaB mediated transcription in SW1353 cells. Twelve effective inhibiting transcription. Especially the roots of P. corymbosa, tragium rhodanta showed potent activities with IC(50) values 2, 3 6 microg/mL, respectively. Five pure compounds, 7 (4-(2-propenyl)phenylangelate), 12 (4-(3-methyloxiranyl)phenyltiglate), 17 (4-methoxy-2-(3-methyloxiranyl)phenyl isobutyrate), 18...