A5101655613- Antibiotic Resistance in Bacteria
- Curcumin's Biomedical Applications
- Advances in Cucurbitaceae Research
- Child Nutrition and Water Access
- Parkinson's Disease Mechanisms and Treatments
- Water Quality and Pollution Assessment
- Carbon and Quantum Dots Applications
- Vibrio bacteria research studies
- Livestock and Poultry Management
- Neonatal Respiratory Health Research
- Heavy Metal Exposure and Toxicity
- Pancreatic and Hepatic Oncology Research
- Selenium in Biological Systems
- Bacterial biofilms and quorum sensing
- Neonatal and fetal brain pathology
- Alzheimer's disease research and treatments
- RNA Interference and Gene Delivery
- Healthcare and Environmental Waste Management
- Innovations in Concrete and Construction Materials
- Erythrocyte Function and Pathophysiology
- Cardiovascular Disease and Adiposity
- Animal Diversity and Health Studies
- Nanopore and Nanochannel Transport Studies
- Biochemical and biochemical processes
- Chromium effects and bioremediation
B.P. Koirala Institute of Health Sciences
2020-2025
Panjab University
2023-2025
Rajasthan University of Veterinary and Animal Sciences
2023-2024
Bihar Agricultural University
2024
Michigan State University
2023-2024
Quantitative BioSciences
2024
Indira Gandhi Institute of Medical Sciences
2022-2024
R.V. College of Engineering
2023
Regional Centre for Biotechnology
2017-2022
National Public Health Laboratory
2022
Acinetobacter species play a significant role in healthcareassociated infections.Multidrug resistance and the ability to form biofilms have made this organism successful hospital pathogen, posing challenge clinicians microbiologists its management.Knowledge about biofilm formation of species, including their antimicrobial status, is crucial for optimizing therapy improving infection control measures.
The study focuses on assessing the contamination levels in Agra Canal, a water source heavily impacted by discharge of effluents from Faridabad, Palwal and small-scale textile bleaching operations; small colonies are situated along its banks, which ultimately flow into Canal. primary objectives this research to evaluate Canal's quality seasonal variations quality. Data was collected during summer, rainy, winter seasons. An array parameters were examined, including pH, E.C., TDS, Turbidity,...
Atherosclerosis is an inflammatory disorder responsible for cardiovascular disease. Reactivation of efferocytosis, the phagocytic removal cells by macrophages, has emerged as a translational target atherosclerosis. Systemic blockade key 'don't-eat-me' molecule, CD47, triggers engulfment apoptotic vascular tissue and potently reduces plaque burden. However, it also induces red blood cell clearance, leading to anemia. To overcome this, we previously developed macrophage-specific nanotherapy...
Deposition of presynaptic protein α-synuclein in Lewy bodies and neurites the substantia nigra region brain has been linked with clinical symptoms Parkinson's disease (PD). Proteotoxic stress conditions mutations that cause abnormal aggregation have close association onset PD its progression. Therefore, studies pertaining to play important roles mechanistic understanding behavior subsequent pathology. Herein, guided by this fact, we studied kinetics, morphology, neurotoxic effects two newly...
Advanced glycation end-products (AGEs) that result from nonenzymatic are one of the major factors involved in diabetes and its secondary complications diseases. This necessitates our urge to discover new compounds may be used as potential AGEs inhibitors without affecting normal structure function biomolecules. In present study, we investigated inhibitory effects AgNP (silver nanoparticles) on formation well their mediated cell toxicity via reactive oxygen species (ROS) production DNA...
The Acinetobacter species is an important hospital-acquired pathogen. rapid development of resistance to multiple drugs and the ability form biofilm make these bacteria more adaptable survive in healthcare facilities, thus posing a challenge their effective management. This study aimed characterize clinical isolates spp antimicrobial susceptibility patterns biofilm. Resistant was further analyzed for detection extended-spectrum β-lactamases (ESBLs), metallo (MBLs), carbapenemase production,...
Abstract Background This study aims to characterize the spectrum of imaging findings in patients Mayer–Rokitansky–Kuster–Hauser (MRKH) syndrome presenting with primary amenorrhoea. Objectives (1) To aid clinical diagnosis MRKH syndrome. (2) detect associated non gynecological anomalies. (3) arrive at optimal management options. Results prospective observational was performed 14 subjects who presented amenorrhoea and diagnosed as on MRI from 1st January, 2021 30 June, 2022. Out patients, 4...
Curcumin (CUR) is a phytochemical with potent anticancer activities as demonstrated by both preclinical and clinical studies. CUR bioformulations, including loading in biodegradable polymers, have been explored to increase CUR’s solubility chemical stability, control its release, improve delivery cancer cells. In this study, copolymers comprising poly (L-lactide)-poly (ethylene glycol)-poly (L-lactide) (PLA-PEG-PLA) glycol) (PEG-PLA-PEG) were designed synthesized assess compare their...
Amyloid formation drives the pathology of different neurodegenerative diseases. α-Synuclein is a natively unfolded protein that assembles itself into toxic amyloid structures, hence contributing to synucleinopathy. Its proceeds through various conformational intermediate stages, starting with lag phase, followed by rapid growth and leading beta rich fibril formation. Few studies have shown helix may be involved in Earlier, was only studied membrane bound state. Despite many years research,...
Chikungunya fever caused by chikungunya virus is an Aedes mosquito borne disease responsible for recent epidemics not only in India but also Africa, Southeast Asia and America. There are no reports of successful anti-viral drug or vaccine available the treatment this fever. Since symptoms very severe, development specific prophylactic measures need h to control known its wealth medicinal plants. Natural compounds from plants have been used traditionally several infectious diseases. Indian...
<i>Background:</i> The impact of HIV on hepatitis C virus (HCV) genome during HCV/HIV co-infection is poorly understood. present study was intended to unveil nucleotide sequence variability in the 5′-untranslated region (5′UTR) HCV co-infected cases. <i>Methods:</i> Automated sequencing 5′UTR from both mono- and cases performed. <i>Results:</i> Data analysis revealed deletion a continuous stretch 12 nucleotides (<i>nt</i> 240–251) domain IIIc...
Background: Staphylococcus aureus is capable of producing a wide range virulence factors. It deadly bacterium that resistant to the majority antibiotics are typically provided. The ability S. establish chronic, implant associated infections and our inability cure them, directly with its biofilm formation, creating an environment where bacteria can grow persist while protected from host immune response antibiotic therapy. Antibiotic resistance widely spreading low rate. Methods: A total 62...
Introduction Due to its ease of use, lack ionizing radiation exposure, noninvasive nature, reproducibility, low cost, and accessibility, ultrasound (US) is the preferred imaging modality for evaluating scrotal disease. High-resolution US color Doppler better highlight testicular diseases because scrotum's superficial anatomy. The genital organs are subjected damaging during CT, while MRI both costly uncommon. Aims objectives aim this study use ultrasonography (USG) examine various diagnose...