- Veterinary Medicine and Surgery
- Muscle and Compartmental Disorders
- Dialysis and Renal Disease Management
- Renal function and acid-base balance
- Veterinary Pharmacology and Anesthesia
- Poisoning and overdose treatments
- Viral Infections and Vectors
- Acute Kidney Injury Research
- Urological Disorders and Treatments
- Pediatric Urology and Nephrology Studies
- Vector-borne infectious diseases
- Pancreatic and Hepatic Oncology Research
- Clinical Nutrition and Gastroenterology
- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Metabolism and Genetic Disorders
- Pancreatitis Pathology and Treatment
- Central Venous Catheters and Hemodialysis
- Veterinary Equine Medical Research
- Antibiotics Pharmacokinetics and Efficacy
- Electrolyte and hormonal disorders
- Inflammatory mediators and NSAID effects
- Zoonotic diseases and public health
- Leptospirosis research and findings
- Veterinary Oncology Research
Tufts University
2016-2025
Tufts Children's Hospital
2022-2024
Cummings Veterinary Medical Center
2021
New England Disabled Sports
2012-2014
Hospital of the University of Pennsylvania
2010
Louisiana State University
2006
MSPCA-Angell
1985
Consensus Statements of the American College Veterinary Internal Medicine (ACVIM) provide veterinarians with guidelines regarding pathophysiology, diagnosis, or treatment animal diseases. The foundation Statement is evidence‐based medicine, but if such evidence conflicting lacking, panel provides interpretive recommendations on basis their collective expertise. intended to be a guide for veterinarians, it not statement standard care substitute clinical judgment. Topics statements and members...
Consensus Statements of the American College Veterinary Internal Medicine (ACVIM) provide veterinarians with guidelines regarding pathophysiology, diagnosis, or treatment animal diseases. The foundation Statement is evidence-based medicine, but if such evidence conflicting lacking, panel provides interpretive recommendations on basis their collective expertise. intended to be a guide for veterinarians, it not statement standard care substitute clinical judgment. Topics statements and members...
An update of the 2006 American College Veterinary Internal Medicine (ACVIM) Small Animal Consensus Statement on Lyme Disease in Dogs: Diagnosis, Treatment, and Prevention was presented at 2016 ACVIM Forum Denver, CO, followed by panel audience discussion a drafted consensus statement distributed online to diplomates for comment. The updated is below. aims provide guidance diagnosis, treatment, prevention borreliosis dogs cats.
The purpose of this report is to offer a consensus opinion ACVIM diplomates on the diagnosis, treatment, and prevention Borrelia burgdorferi infections in dogs (canine Lyme disease). Clinical syndromes known commonly be associated with canine disease include polyarthritis glomerulopathy. Serological test results can used document exposure B. but not prove illness. Although serum enzyme‐linked immunosorbent assay/indirect fluorescent antibody assay titers stay positive for months years after...
The purpose of this report is to offer a consensus opinion ACVIM diplomates on the diagnosis, treatment, and prevention Borrelia burgdorferi infections in dogs (canine Lyme disease).Clinical syndromes known commonly be associated with canine disease include polyarthritis glomerulopathy.Serological test results can used document exposure B. but not prove illness.Although serum enzyme-linked immunosorbent assay/indirect fluorescent antibody assay titers stay positive for months years after...
There are many causes of kidney disease in dogs. The association the diagnostic category with survival is unknown. Determine outcomes for biopsy-determined categories Six hundred forty-nine dogs were biopsied evaluation disease. Retrospective study. Survival information was obtained whose biopsy submitted to International Veterinary Renal Pathology Service between 2008 and 2018. Signalment, serum creatinine (sCr), urine protein : ratio (UPCR), albumin (sAlb) reported at time biopsy. Cox...
The purpose of this report was to provide consensus recommendations for the use immunosuppressive therapy in dogs with active glomerular diseases. Recommendations were developed based on comprehensive review relevant literature disease and humans, contemporary expert opinion, anecdotal experience treated immunosuppression. subsequently validated by a formal methodology. Study Group recommends empirical application severe, persistent, or progressive which there is evidence an immune‐mediated...
The sonographic appearance of the feline pancreas and associated anatomic landmarks including pancreatic duct, duodenum, duodenal papilla, portal vein, gastric lymph node were evaluated in 20 healthy, awake cats. appeared nearly isoechoic to surrounding mesenteric tissues, slightly hyperechoic adjacent liver lobes, hypoechoic spleen. mean thickness measurements for right lobe, body, left lobe 4. 5 mm (range 2. 8–5. 9), 6. 6 7–9. 5), 5. 4 3. 4–9. 0), respectively. duct was consistently...
The purpose of this retrospective study was to evaluate the use partial parenteral nutrition (PPN) in dogs and cats. medical records all cats receiving PPN between 1994 1999 were reviewed determine signalment, reasons for PPN, duration administration, hospitalization, complications, mortality. Complications classified as metabolic, mechanical, or septic. One hundred twenty‐seven animals (80 47 cats) included study, accounting 443 patient days PPN. most common underlying diseases pancreatitis...
The objective of this study was to describe the dietary and medication patterns cats with chronic kidney disease (CKD). In prospective, cross-sectional descriptive study, owners CKD were asked complete a web-based survey. advertised on CKD-, pet-, veterinary- breed-associated websites list serves. Owners 1089 participated in study. mean reported age 13.7 ± 4.2 years. Forty percent (430/1089) had concurrent diseases, hyperthyroidism, heart inflammatory bowel being most common. Veterinarian...
Novel biomarkers are needed in diagnosing reliably acute kidney injury (AKI) dogs and predicting morbidity mortality after AKI. Our hypothesis was that two novel tubular biomarkers, urinary clusterin (uClust) cystatin B (uCysB), elevated with AKI of different etiologies. In a prospective, longitudinal observational study, we collected serum urine samples from 18 severity various etiology 10 healthy control dogs. Urinary uCysB were compared at inclusion between controls remeasured one three...
Since SARS-CoV-2 lineage BA.5 (Omicron) emerged and spread in 2022, Omicron lineages have massively diversified.Here, we review the evolutionary trajectories processes underpinning emergence of these lineages, identify most prevalent sublineages.We discuss potential origins second-generation BA.2 lineages.Simple complex recombination, antigenic drift convergent evolution enabled to accumulate mutations that alter its antigenicity.We also likely future SARS-CoV-2.
A randomized, double-blind, controlled study was performed with 18 arthritic dogs administered aspirin (25 mg/kg of body weight, PO, q 8 h) and excipient (control group) or misoprostol (100 micrograms, h). Dogs in the (n = 10) control 8) groups were primarily compared by use sequential gastroduodenoscopy, changes PCV, prevalence clinical signs gastrointestinal disturbance over a 14-day treatment period. The misoprostol/aspirin-treated group had significantly (P < 0.05) less gastroduodenal...
Peritoneal dialysis (PD) has been described for use in animals with acute kidney injury refractory to fluid therapy. However, no study examined the of PD a large group cats.PD is an important adjunctive therapy treat cats.The medical records 22 cats that had received were examined. Animals excluded if uremia was result postrenal causes such as uroabdomen or urethral obstruction.Medical reviewed following: indication PD, outcome, number cycles performed, survival time, and predialysis...
Darbepoetin alfa (darbepoetin) is an erythropoiesis-stimulating agent used for the treatment of anemia secondary to chronic kidney disease (CKD) in dogs, but reports describing response are lacking.To evaluate effectiveness darbepoetin dogs with CKD, dosing protocols, and adverse events.Thirty-three client-owned naturally occurring including 26 comorbidities.Multi-institutional retrospective study.The median starting dosage highest administered were 0.5 0.8 μg/kg SC once weekly,...
Background Therapeutic plasma exchange (TPE) may be an effective technique for treatment of accidental nonsteroidal anti‐inflammatory drug (NSAID) overdose, but information regarding the use this in veterinary medicine is currently limited. Objectives To evaluate overall outcome dogs with NSAID overdose treated TPE and to determine if any presenting factors can predict or influence outcome. Secondary objectives included investigating complications as well utility other adjunctive treatments....
Summary Peritoneal dialysis is an effective modality for the treatment of acute and chronic renal failute, specific intoxications, electrolyte abnormalities, fluid overload. This review peritoneal as it applies to veterinary critical care setting includes: indications contraindications dialysis; selection placement catheters; description delivery technique; considerations monitoring patient common complications therapy. If appropriately applied, a viable tool in care.