A5004725422- Crystallization and Solubility Studies
- Click Chemistry and Applications
- Food Quality and Safety Studies
- X-ray Diffraction in Crystallography
- Photoreceptor and optogenetics research
- Synthesis and biological activity
- DNA and Nucleic Acid Chemistry
- Oxidative Organic Chemistry Reactions
- Radical Photochemical Reactions
- Lung Cancer Treatments and Mutations
- Advanced Chemical Sensor Technologies
- Advanced biosensing and bioanalysis techniques
Polish Academy of Sciences
2023-2024
Institute of Physical Chemistry
2023-2024
The first-in-class luminescent dinucleoside phosphate analogs with a [Re2(μ-Cl)2(CO)6(μ-pyridazine)] "click" linker as replacement for the natural group are reported together synthesis of adenosine and thymidine derivatives having entity attached to positions 5' 3', respectively. These compounds were synthesized by applying inverse-electron-demand Diels-Alder copper(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition reactions in three or four steps. obtained exhibited orange emission (λPL ≈...
Conjugation of organometallic entities to drug molecules is a strategy that often results in products with new biological activity profiles compared those their progenitors. In this study, we utilized CuAAC and RuAAC reactions synthesize series organometallic–erlotinib conjugates. Erlotinib an important anti-non-small cell lung cancer epidermal growth factor receptor tyrosine kinase (EGFR TK) inhibitory activity. Our studies show ferrocenyl–erlotinib conjugates are more anticancer active...
We propose a new, simple and general procedure of light-driven deoxygenation solutions based on hydroperoxides formation upon irradiation. Efficient fast removal molecular oxygen is caused by photosensitized...