A5061976414- Pregnancy and Medication Impact
- Maternal and fetal healthcare
- Cancer-related molecular mechanisms research
- Lipid metabolism and disorders
- Pregnancy and preeclampsia studies
- Biomedical Research and Pathophysiology
- Systemic Lupus Erythematosus Research
- Maternal and Perinatal Health Interventions
- Epigenetics and DNA Methylation
- Long-Term Effects of COVID-19
- Genomics and Chromatin Dynamics
- Circular RNAs in diseases
- COVID-19 Clinical Research Studies
- Neurological Complications and Syndromes
- Lipoproteins and Cardiovascular Health
- Angiogenesis and VEGF in Cancer
- RNA modifications and cancer
- MicroRNA in disease regulation
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Renal Diseases and Glomerulopathies
Czech Academy of Sciences, Institute of Physiology
2023
University of California, Los Angeles
2020-2022
Jawaharlal Institute of Post Graduate Medical Education and Research
2020
Rates of cesarean delivery (CD) are increased among transplant recipients. There is a need to define the indications for CD and associated outcomes recipients determine safest mode obstetric delivery.
OBJECTIVE: To evaluate the clinical and laboratory characteristics in pregnancy that differentiate preeclampsia from acute renal allograft rejection to investigate maternal, neonatal, graft sequelae of these diagnoses. METHODS: We conducted a retrospective case-controlled registry study data abstracted Transplant Pregnancy Registry International deliveries between 1968 2019. All adult kidney transplant recipients with singleton pregnancies at least 20 weeks gestation were included. Acute was...
Long noncoding RNAs (lncRNAs) have emerged as key mediators of regulated gene expression in diverse biologic contexts, including cardiovascular disease. In this issue the JCI, Tang, Luo, and colleagues explored contributions lncRNAs diabetic vasculopathy. The authors identified lncRNA LEENE a mediator angiogenesis ischemic response. model peripheral arterial disease, loss led to impaired vascular perfusion, while its overexpression rescued defect. used unbiased chromatin affinity assays...
Pregnancies after solid organ transplant are at a higher risk of antepartum admission and pregnancy complications including cesarean delivery. Emergent prelabor delivery is associated with increased maternal neonatal morbidity in other high-risk populations, but its incidence impact recipients not well-understood.This study aimed to characterize the factors outcomes emergency kidney liver recipients.This was retrospective cohort all >20 weeks gestation enrolled Transplant Pregnancy Registry...
The three-dimensional organization of the genome plays an important role in cellular function. Alterations between open and closed chromatin states contributes to DNA binding, collaborative transcriptional activities informs post-transcriptional processing. liver orchestrates systemic metabolic control has ability mount a rapid adaptive response environmental challenges. We interrogated architecture under different dietary cues. Using ATAC-seq, we mapped over 120,000 nucleosome peaks,...
ABSTRACT Background Vascular thrombosis is common in patients with coronavirus disease 2019 (COVID-19). Etiologies underlying this complication are unclear. Purpose To determine the prevalence of antiphospholipid (aPL), including lupus anticoagulant, anti-cardiolipin and anti-β2-glycoprotein-1 antibodies, its possible association thrombotic manifestations COVID-19. Data Sources We searched MEDLINE indexed journals on September 24, 2020 using tool LitCovid pre-print server medRxIV. Study...