A5069191858- Birth, Development, and Health
- Effects and risks of endocrine disrupting chemicals
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Health and Contraception
- Reproductive Health and Technologies
- Ovarian function and disorders
- Cancer Risks and Factors
- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Family Dynamics and Relationships
- Per- and polyfluoroalkyl substances research
- Toxic Organic Pollutants Impact
- Noise Effects and Management
- Air Quality and Health Impacts
- Electromagnetic Fields and Biological Effects
- Estrogen and related hormone effects
- Maternal Mental Health During Pregnancy and Postpartum
- Climate Change and Health Impacts
- Nutritional Studies and Diet
- Pregnancy and Medication Impact
- Health, Environment, Cognitive Aging
- Reproductive System and Pregnancy
- Sperm and Testicular Function
- Global Health Care Issues
- Demographic Trends and Gender Preferences
Boston University
2016-2025
University of Washington
2024
Walsall Manor Hospital
2024
National Institute of Allergy and Infectious Diseases
2023
University of San Francisco
2023
University of California, Los Angeles
2023
Brown University
2023
Providence College
2023
Creative Commons
2023
Faculty of 1000 (United States)
2023
Polyfluoroalkyl chemicals (PFCs) are used commonly in commercial applications and detected humans the environment worldwide. Concern has been raised that they may disrupt lipid weight regulation.We investigated relationship between PFC serum concentrations outcomes a large publicly available data set.We analyzed from 20032004 National Health Nutrition Examination Survey (NHANES) for participants 1280 years of age. Using linear regression to control covariates, we studied association...
Concern has arisen that the use of hand-held cellular telephones might cause brain tumors. If such a risk does exist, matter would be considerable public health importance, given rapid increase worldwide in these devices.
Previous studies found associations between childhood leukemia and surrogate indicators of exposure to magnetic fields (the power-line classification scheme known as "wire coding"), but not measurements 60-Hz residential fields.
Although diet and activity are key factors in the obesity epidemic, laboratory studies suggest that endocrine disrupting chemicals may also affect obesity. We analyzed associations between six phthalate metabolites measured urine body mass index (BMI) waist circumference (WC) National Health Nutrition Examination Survey (NHANES) participants aged 6–80. included 4369 from NHANES 1999–2002, with data on mono-ethyl (MEP), mono-2-ethylhexyl (MEHP), mono-n-butyl (MBP), mono-benzyl (MBzP)...
Before 1971, several million women were exposed in utero to diethylstilbestrol (DES) given their mothers prevent pregnancy complications. Several adverse outcomes have been linked such exposure, but cumulative effects are not well understood.We combined data from three studies initiated the 1970s with continued long-term follow-up of 4653 DES and 1927 unexposed controls. We assessed risks 12 including 45 years age for reproductive 55 other outcomes, relationships baseline presence or absence...
Abstract It has been hypothesized that breast cancer risk is influenced by prenatal hormone levels. Diethylstilbestrol (DES), a synthetic estrogen, was widely used pregnant women in the 1950s and 1960s. Women who took drug have an increased of cancer, but whether also daughters were exposed utero less clear. We assessed relation DES exposure to cohort DES-exposed unexposed followed since 1970s mailed questionnaires. Eighty percent both completed most recent questionnaire. Self-reports...
Some reproductive-aged individuals remain unvaccinated against coronavirus disease 2019 (COVID-19) because of concerns about potential adverse effects on fertility. Using data from an internet-based preconception cohort study, we examined the associations COVID-19 vaccination and severe acute respiratory syndrome 2 (SARS-CoV-2) infection with fertility among couples trying to conceive spontaneously. We enrolled 2,126 self-identified female participants aged 21-45 year residing in United...
Recent studies have shown that both female and male obesity may delay time-to-pregnancy (TTP). Little is known about central adiposity or weight gain fecundability in women.We examined the association between anthropometric factors TTP among 1651 Danish women participating an internet-based prospective cohort study of pregnancy planners (2007-2008). We categorized body mass index (BMI = kg/m(2)) as underweight (<20), normal (20-24), overweight (25-29), obese (30-34) very (> =35). used...
An association between prenatal diethylstilbestrol (DES) exposure and cancer in men, especially testicular cancer, has been suspected, but findings from case-control studies have inconsistent. This study was conducted to investigate the DES risk men via prospective follow-up.A total of 3613 whose status known were followed 1978 through 1994. The overall site-specific incidence rates among DES-exposed compared with those unexposed population-based rates. relative rate (RR) used assess...
The association between in utero exposure to diethylstilbestrol (DES) and clear cell adenocarcinoma (CCA) of the vagina cervix is well known, yet there has been no systematic study DES-exposed daughters determine whether they have an increased risk other cancers. As many as 3 million women United States may exposed DES utero.To a higher cancer after average 16 years follow-up.A cohort with mailed questionnaires medical record review reported outcomes.A 4536 (of whom 81% responded) 1544...
Abstract Prenatal diethylstilbestrol (DES) exposure is associated with excess risks of clear cell adenocarcinoma (CCA), and breast cancer in older women. Whether overall risk also elevated unclear. Total site‐specific were evaluated the DES Combined Cohort Follow‐up Study using age‐ calendar‐year specific standardized incidence rate ratios (SIR), age‐adjusted (RR) comparing exposed unexposed A total 143 49 cases occurred 97,831 34,810 person‐years among unexposed, respectively. There was no...
Journal Article EFFECT OF MARIJUANA USE IN PREGNANCY ON FETAL GROWTH Get access ELIZABETH E. HATCH, HATCH From the Perinatal Epidemiology Unit, and Departments of Public Health, Obstetrics Gynecology, Yale University Medical SchoolNew Haven, CT Search for other works by this author on: Oxford Academic PubMed Google Scholar MICHAEL B. BRACKEN Reprint requests to Dr. Michael Bracken, Department School, 60 College Street, New 06510. American Epidemiology, Volume 124, Issue 6, December 1986,...
Abstract Background We launched the B oston U niversity P regnancy S tudy O nline ( PRESTO ) to assess feasibility of carrying out an I nternet‐based preconception cohort study in US and C anada. Methods recruited female participants age 21–45 their male partners through nternet advertisements, word mouth, flyers. Female were randomised with 50% probability receive a subscription FertilityFriend.com FF ), web‐based programme that collects real‐time data on menstrual characteristics. compared...
Diethylstilbestrol (DES), a synthetic estrogen widely prescribed to pregnant women during the 1940s-70s, has been shown cause reproductive problems in daughters. Studies of prenatally-exposed males have yielded conflicting results. In data from collaborative follow-up three U.S. cohorts DES-exposed sons, we examined relation prenatal DES exposure occurrence male urogenital abnormalities. Exposure status was determined through review records. Mailed questionnaires (1994, 1997, 2001) asked...
Bisphenol A (BPA) and polyfluoroalkyl chemicals (PFCs) are suspected endocrine disrupting compounds known to be ubiquitous in people's bodies. Population disparities exposure these have not been fully characterized. We analyzed data from the 2003-2006 National Health Nutrition Examination Survey. Using multivariable linear regression we examined association between urinary concentrations of BPA, serum four PFCs, multiple measures socioeconomic position (SEP): family income, education,...
Selection bias is a potential concern in all epidemiologic studies, but it usually difficult to assess. Recently, concerns have been raised that internet-based prospective cohort studies may be particularly prone selection bias. Although use of the internet efficient and facilitates recruitment subjects are otherwise enroll, any compromise internal validity would great concern. Few evaluated studies. Using data from Danish Medical Birth Registry 2008 2012, we compared six well-known...
ABSTRACT Background Epidemiologic studies have demonstrated that ambient concentrations of particulate matter < 2.5 μm (PM ) are associated with reduced fecundability, the per cycle probability conception. The specific constituents driving this association unknown. Objectives We examined between PM and fecundability in a Danish preconception cohort study. Methods During 2007–2018, we enrolled female pregnancy planners an Internet‐based included 5905 participants who had been trying to...
Causes of brain tumors are largely unknown, and there is an urgent need to identify possible risk factors. Several observations point a role reproductive hormones, but few epidemiologic studies have examined whether factors, such as age at menarche parity, associated with tumor risk. We conducted multi-center case-control study newly diagnosed glioma (n = 212) meningioma 151) frequency-matched controls 436) in women from hospitals Phoenix, Arizona; Boston, Massachusetts; Pittsburgh,...