Alexis M. Walker

ORCID: 0000-0001-7909-5003
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About
Contact & Profiles
Research Areas
  • Microbial Community Ecology and Physiology
  • Environmental DNA in Biodiversity Studies
  • Indigenous Studies and Ecology
  • Monoclonal and Polyclonal Antibodies Research
  • Methane Hydrates and Related Phenomena
  • RNA and protein synthesis mechanisms
  • Climate change and permafrost
  • Plant Molecular Biology Research
  • Plant Reproductive Biology
  • CAR-T cell therapy research
  • Advanced Biosensing Techniques and Applications
  • Marine and coastal ecosystems
  • Glycosylation and Glycoproteins Research
  • Photosynthetic Processes and Mechanisms

University of Colorado Boulder
2024

University of Alaska Fairbanks
2021-2022

Brown University
2009

Kansas State University
2009

Max Planck Institute for Plant Breeding Research
2009

Like many species, the model plant Arabidopsis thaliana exhibits multiple different life histories in natural environments. We grew mutants impaired signaling pathways field experiments across species' native European range order to dissect mechanisms underlying this variation. Unexpectedly, mutational loss at loci implicated cold requirement for flowering had little effect on history except late-summer cohorts. A genetically informed photothermal of progression toward explained most...

10.1126/science.1165826 article EN Science 2009-01-16

Antibodies are engineerable quantities in medicine. Learning antibody molecular recognition would enable the silico design of high affinity binders against nearly any proteinaceous surface. Yet, publicly available experiment sequence-binding datasets may not contain mutagenic, antigenic, or sequence diversity necessary for deep learning approaches to capture recognition. In part, this is because limited experimental platforms exist assessing quantitative and simultaneous sequence-function...

10.1038/s41467-024-48072-z article EN cc-by Nature Communications 2024-05-10

The paradigm of tight pelagic-benthic coupling in the Arctic suggests that current and future fluctuations sea ice, primary production, riverine input resulting from global climate change will have major impacts on benthic ecosystems. To understand how these changes affect ecosystem function, we must characterize diversity, spatial distribution, community composition for all faunal components. Bacteria archaea link biotic abiotic realms, playing important roles organic matter (OM)...

10.3389/fmicb.2021.581124 article EN cc-by Frontiers in Microbiology 2021-01-28
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