- Medical Image Segmentation Techniques
- Computer Graphics and Visualization Techniques
- Advanced Neuroimaging Techniques and Applications
- Trigeminal Neuralgia and Treatments
- 3D Shape Modeling and Analysis
- Advanced MRI Techniques and Applications
- Intracranial Aneurysms: Treatment and Complications
- Functional Brain Connectivity Studies
- Facial Nerve Paralysis Treatment and Research
- Vascular Malformations Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Meningioma and schwannoma management
- Digital Image Processing Techniques
- Tensor decomposition and applications
- Botulinum Toxin and Related Neurological Disorders
- Medical Imaging and Analysis
- Anatomy and Medical Technology
- Fetal and Pediatric Neurological Disorders
- Geological Modeling and Analysis
- Elasticity and Material Modeling
- Robotics and Sensor-Based Localization
- Glioma Diagnosis and Treatment
- Cerebral Venous Sinus Thrombosis
- Neurosurgical Procedures and Complications
Universitätsklinikum Erlangen
2008-2023
Friedrich-Alexander-Universität Erlangen-Nürnberg
2007-2022
University Hospital Schleswig-Holstein
2011
University of Lübeck
2011
University Hospital Ulm
2011
Institute of Electrical and Electronics Engineers
2006
Massachusetts General Hospital
2005
University of Stuttgart
2002
OBJECTIVE Modern neuronavigation systems lack spatial accuracy during ongoing surgical procedures because of increasing brain deformation, known as shift. Intraoperative magnetic resonance imaging was used for quantitative analysis and visualization this phenomenon. METHODS For a total 64 patients, we 0.2-T, open-configuration, scanner, located in an operating theater, pre- intraoperative imaging. The three-dimensional data were aligned using rigid registration methods. maximal displacements...
Abstract OBJECTIVE: To investigate the intraoperative displacement of major white matter tracts during glioma resection by comparing preoperative and diffusion tensor imaging-based fiber tracking. METHODS: In 37 patients undergoing surgery, imaging was performed with a 1.5-T magnetic resonance scanner applying an echo-planar sequence six directions. For three-dimensional tractography, we implemented knowledge-based multiple-region-of-interest approach user-defined seed regions in color-coded...
PURPOSE: To prospectively evaluate the location of white matter tracts with diffusion-tensor imaging (DTI) during neurosurgical procedures. MATERIALS AND METHODS: Ethical committee approval and signed informed consent were obtained. A 1.5-T magnetic resonance imager an adapted rotating surgical table that is placed in a radiofrequency-shielded operating theater was used for pre- intraoperative imaging. DTI performed by applying echo-planar sequence six diffusion directions 38 patients (20...
<h3>BACKGROUND AND PURPOSE:</h3> High-resolution MR imaging is useful for diagnosis and preoperative planning in patients with NVC. Because high-field promises higher SNR resolution, the aim of this study was to determine value high-resolution 3D-CISS 3D-TOF MRA at 3T compared 1.5T <h3>MATERIALS METHODS:</h3> Forty-seven NVC, trigeminal neuralgia, hemifacial spasm, glossopharyngeal neuralgia were examined 3T, including sequences. Delineation anatomic structures, overall image quality,...
Glossopharyngeal neuralgia is a rare condition with neuralgic sharp pain in the pharyngeal and auricular region. Classical glossopharyngeal caused by neurovascular compression at root entry zone of nerve. Regarding occurrence neuralgia, we report clinical data magnetic resonance imaging (MRI) findings case series 19 patients, whom 18 underwent surgery. Two patients additionally suffered from trigeminal three additional symptomatic vagal nerve compression. In all ipsilateral syndrome IX...
Object In this paper, the authors introduce a method of noninvasive anatomical analysis facial nerve–vestibulocochlear nerve complex and depiction variable vascular relationships by using 3D volume visualization. With technique, detailed spatial representation vestibulocochlear nerves was obtained. Patients with hemifacial spasm (HFS) resulting from neurovascular compression (NVC) were examined. Methods A total 25 patients (13 males 12 females) HFS underwent visualization magnetic resonance...
Reliable elasticity parameters describing the behavior of a given material are an important issue in context physically-based simulation. In this paper we introduce method for determination mechanical properties brain tissue. Elasticity Young's modulus E and Poisson's ratio ν estimated iterative framework coupling finite element simulation with image registration. Within framework, outcome is parameterized both moduli that automatically varied until optimal correspondence between simulated...
Nimsky, Christopher M.D.; Ganslandt, Oliver Hastreiter, Peter Ph.D.; Wang, Ruopeng Benner, Thomas Sorensen, A. Gregory Fahlbusch, Rudolf M.D.
Line integral convolution (LIC) is an effective technique for visualizing vector fields. The application of LIC to 3D flow fields has yet been limited by difficulties efficiently display and animate the resulting 3D-images. Texture-based volume rendering allows interactive visualization manipulation 3D-LIC textures. In order ensure comprehensive convenient exploration fields, we suggest functionality including transfer functions different clipping mechanisms. Thereby, substitute calculation...
For a comprehensive understanding of tomographic image data in medicine, interactive and high-quality direct volume rendering is an essential prerequisite. This provided by visualization using 3D texture mapping which still limited to high-end graphics hardware. In order make it available clinical environment, we present system uniquely combines local desktop computers remote this context, exploit the standard capabilities maximum are environment. representations high resolution quality...
Object. The goal of this study was to describe the authors' technique for three-dimensional (3D) visualization neurovascular relationships in posterior fossa at surface brainstem. This is based on processing high-resolution magnetic resonance (MR) imaging data. principles and technical details involved accurate simultaneous vessels cranial nerves as tiny structures are presented using explicit implicit segmentation well volume rendering. Methods. In approach 3D MR constructive interference...
Figure 1: Samples generated with our diffusion tensor visualization application.(a) shows automatically clustered whole brain tracking assigned colors.(b) displays the optic tract (orange) and pyramidal (blue) in combination direct volume rendering of high resolution magnetic resonance data.(c) is an example for safety estimation use staggered hulls.(d) color encoded cluster segments corpus callosum combined MRI T 1 data.
Diffusion tensor imaging is of high value in neurosurgery, providing information about the location white matter tracts human brain. For their reconstruction, streamline techniques commonly referred to as fiber tracking model underlying structures and have therefore gained interest. To meet requirements surgical planning overcome visual limitations line representations, a new real-time visualization approach quality introduced. this purpose, textured triangle strips point sprites are...
Line integral convolution (LIC) is an effective technique for visualizing vector fields. The application of LIC to 3D flow fields has yet been limited by difficulties efficiently display and animate the resulting 3D-images. Texture-based volume rendering allows interactive visualization manipulation 3D-LIC textures. In order ensure comprehensive convenient exploration fields, we suggest functionality including transfer functions different clipping mechanisms. Thereby, substitute calculation...
Different imaging modalities give insight to vascular, anatomical and functional information which assist diagnosis therapy planning in medicine. Registration consecutive visualization allow combine the image data thereby convey more meaningful images clinician. Applying a voxel based approach on mutual information, accurate retrospective registration is provided. However, optimization procedures require huge amount of trilinear interpolation operations re-sample data. Ensuring fast...
Object The authors systematically analyzed 3D visualization of neurovascular compression (NVC) syndromes in the operating room (OR) during microvascular decompression (MVD). Methods A total 50 patients (26 women and 24 men) with trigeminal neuralgia (TN), hemifacial spasm (HFS), glossopharyngeal (GN) were examined underwent MVD. Preoperative imaging structures was performed using constructive interference steady state magnetic resonance (CISS MR) imaging, which consisted 2D image slices....
Computed tomography (CT) is the modality of choice for detailed imaging bony labyrinth. Usually, information about complex three-dimensional anatomic structures inner ear presented as two-dimensional section images. Interactive direct volume rendering a powerful method visualization Unlike other methods, enables labyrinth without explicit segmentation prior to process. Direct was applied temporal bone in five patients pathologic conditions and four with conditions. In all cases, clear...
The increasing capabilities of magnetic resonance (MR) imaging and multisection spiral computed tomography (CT) to acquire volumetric data with near-isotropic voxels make three-dimensional (3D) postprocessing a necessity, especially in studies complex structures like intracranial vessels. Since most modern CT MR imagers provide limited capabilities, 3D visualization interactive direct volume rendering requires expensive graphics workstations that are not available at many institutions. An...