- Computer Graphics and Visualization Techniques
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- 3D Shape Modeling and Analysis
- Radiation Dose and Imaging
- Advanced Vision and Imaging
- Surface and Thin Film Phenomena
- Anatomy and Medical Technology
- Medical Image Segmentation Techniques
- Advanced X-ray Imaging Techniques
- Quantum and electron transport phenomena
- Advanced Semiconductor Detectors and Materials
- AI in cancer detection
- Rheumatoid Arthritis Research and Therapies
- Geological Modeling and Analysis
- Computational Geometry and Mesh Generation
- Force Microscopy Techniques and Applications
- Semiconductor Quantum Structures and Devices
- Digital Image Processing Techniques
- Radiation Detection and Scintillator Technologies
- Advanced MRI Techniques and Applications
- Digital Imaging in Medicine
- Data Visualization and Analytics
- Molecular Junctions and Nanostructures
- Theoretical and Computational Physics
Siemens Healthcare (Germany)
2016-2024
University College London
2024
European Synchrotron Radiation Facility
2024
Université Grenoble Alpes
2024
RWTH Aachen University
2024
Johannes Gutenberg University Mainz
2024
Philips (Germany)
2006-2022
Philips (Netherlands)
2012-2020
Siemens Healthcare (United States)
2019
Amsterdam Scientific Instruments (Netherlands)
2015
We introduce a novel texture-based volume rendering approach that achieves the image quality of best post-shading approaches with far less slices. It is suitable for new flexible consumer graphics hardware and provides high even low-resolution data non-linear transfer functions frequencies, without performance overhead caused by additional interpolated This especially useful volumetric effects in computer games professional scientific visualization, which heavily depend on memory bandwidth...
Interactive direct volume rendering has yet been restricted to high-end graphics workstations and special-purpose hardware, due the large amount of trilinear interpolations, that are necessary obtain high image quality. Implementations use 2D-texture capabilities standard PC usually render object-aligned slices in order substitute by bilinear interpolation. However resulting images often contain visual artifacts caused lack spatial In this paper we propose new techniques significantly...
Background Current clinical imaging modalities such as CT and MRI provide resolution adequate to diagnose cardiovascular diseases but cannot depict detailed structural features in the heart across length scales. Hierarchical phase-contrast tomography (HiP-CT) uses fourth-generation synchrotron sources with improved x-ray brilliance high energies micron-resolution of intact adult organs unprecedented detail. Purpose To evaluate capability HiP-CT macro- microanatomy structurally normal...
We propose clipping methods that are capable of using complex geometries for volume clipping. The tests exploit per-fragment operations on the graphics hardware to achieve high frame rates. In combination with texture-based rendering, these techniques enable user interactively select and explore regions data set. present depth-based analyze depth structure boundary representation clip geometry decide which parts have be clipped. another approach, a voxelized object is used identify clipped...
To test whether the presence of structural entheseal lesions in psoriasis patients influences risk progression to psoriatic arthritis (PsA).We conducted a prospective cohort study without clinical evidence musculoskeletal involvement who underwent baseline assessment and volumetric bone mineral density (vBMD) at intraarticular sites by high-resolution peripheral quantitative computed tomography. Adjusted relative risks developing PsA associated with vBMD were calculated using multivariable...
Imaging detectors for medical X-ray and computed tomography (CT) applications have undergone many improvements technology changes over time. But most (dynamic) sold in this field still rely on indirect conversion, using scintillators photodiodes to convert the quanta ultimately into electrical signals. Direct conversion promise very high spatial resolution signal-to-noise ratios. Some direct materials may allow counting or even energy resolving detection of quanta. Based this, example...
For medical imaging applications, such as cardiac imaging, dual-source computed tomography (CT) improves the temporal resolution by simultaneous use of two cone beams, which acquire twice many projections single-source CT does within same time interval. Besides this advantage, a drawback system is additional x-ray scatter originating from extra (cross-illuminating) beam. In work, comparison with images performed under same-dose conditions for different thorax phantoms, and beam angles...
To investigate the properties of tomographic grating-based phase contrast imaging with respect to its noise power spectrum and energy dependence achievable ratio.Tomographic simulations an object 11 cm diameter constituted materials biological interest were conducted at different energies ranging from 25 85 keV by using a wave propagation approach. Using Monte Carlo simulation x-ray attenuation within object, it is verified that simulated measurement deposits same dose each energy.The in...
Abstract Background Currently, alternative medical imaging methods for the assessment of pulmonary involvement in patients infected with COVID-19 are sought that combine a higher sensitivity than conventional (attenuation-based) chest radiography lower radiation dose CT imaging. Methods Sixty COVID-19-associated lung changes scan and 40 subjects without pathologic visible were included (in total, 100, 59 male, mean age 58 ± 14 years). All gave written informed consent. We employed clinical...
For a comprehensive understanding of tomographic image data in medicine, interactive and high-quality direct volume rendering is an essential prerequisite. This provided by visualization using 3D texture mapping which still limited to high-end graphics hardware. In order make it available clinical environment, we present system uniquely combines local desktop computers remote this context, exploit the standard capabilities maximum are environment. representations high resolution quality...
We propose new clipping methods that are capable of using complex geometries for volume clipping. The tests exploit per-fragment operations on the graphics hardware to achieve high frame rates. In combination with texture-based rendering, these techniques enable user interactively select and explore regions data set. present depth-based analyze depth structure boundary representation clip geometry decide which parts have be clipped. another approach, a voxelized object is used identify...
The need for fine detail visibility in various applications such as dental imaging, mammography, but also neurology and cardiology, is the driver intensive efforts development of new x‐ray detectors. spatial resolution current scintillator layers limited by optical diffusion. This limitation can be overcome a pixelation, which prevents photons from crossing interface between two neighboring pixels. In this work, an array pores was etched silicon wafer with pixel pitch . A very high aspect...
CIX is a direct converting hybrid pixel detector designed for medical X-ray imaging applications. Its key feature the simultaneous counting and integrating of absorbed quanta, which offers, among other benefits, large dynamic range as well opportunity to calculate average photon energy spectrum. In this work several different Si, CdTe CdZnTe sensors are characterized their suitability sensor materials combined system assessed. The measurements indicate that temporal stability an issue tested...
The reconstruction of isosurfaces from scalar volume data has positioned itself as a fundamental visualization technique in many different applications. But the dramatically increasing size volumetric sets often prohibits handling these models on affordable low-end single processor architectures. Distributed client-server systems integrating high-bandwidth transmission channels and Web-based tools are one alternative to attack this particular problem, but therefore new approaches reduce load...
Patient education is crucial for successful chronic disease management. Current material rheumatic patients however rarely includes images of pathologies, limiting patients' understanding. Cinematic rendering (CR) a new tool that allows segmentation standard medical (DICOMs) into pictures illustrate pathologies in photorealistic way. Thus CR has the potential to simplify and improve explanation activity consequences could therefore be valuable effectively educate inform about their...
We present a volume visualization framework that allows high-quality interactive rendering of teravoxel scale data sets on standard PCs. It is based progressive multi-resolution out-of-core approach. Data loading controlled by rays are cast through the set. The tree structure representing hierarchy traversed and updated directly GPU during ray casting. Consequently, occluded empty never loaded or rendered. able to render dense, anisotropic, scalar regular grids with all common modes.