A5100421328- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- Nanopore and Nanochannel Transport Studies
- Molecular Communication and Nanonetworks
- Microbial Metabolic Engineering and Bioproduction
- Microtubule and mitosis dynamics
- Microbial metabolism and enzyme function
- Power Systems and Renewable Energy
- Advanced Image and Video Retrieval Techniques
- Single-cell and spatial transcriptomics
- Gene Regulatory Network Analysis
- Advanced Data Compression Techniques
- Microfluidic and Bio-sensing Technologies
- Micro and Nano Robotics
- DNA and Nucleic Acid Chemistry
- Energy Load and Power Forecasting
- Image Retrieval and Classification Techniques
- Advanced Materials and Mechanics
- Biochemical Acid Research Studies
- GABA and Rice Research
- Polyamine Metabolism and Applications
- Neural Networks and Applications
University of Washington
2005-2022
Johns Hopkins University
2018-2022
Jinan University
2019
Self-assembled DNA nanostructures have potential applications in therapeutics, diagnostics, and synthetic biology. A challenge using biological environments or cell culture, however, is that they may be degraded by enzymes found these environments, such as nucleases. Such degradation can slowed introducing alternative substrates for nucleases, coating with membranes peptides. Here we demonstrate a means which reversed situ through the repair of nanostructure defects. To this effect, show...
Designed and engineered protein DNA nanopores can be used to sense characterize single molecules control transmembrane transport of molecular species. However, designed biomolecular pores are less than 100 nm in length primarily for across lipid membranes. Nanochannels that span longer distances could as conduits between nonadjacent compartments or cells. Here, we design micrometer-long, 7-nm-diameter nanochannels small traverse according the laws continuum diffusion. Binding origami caps...
Mesoscale molecular assemblies on the cell surface, such as cilia and filopodia, integrate information, control transport amplify signals. Synthetic devices mimicking these structures could sensitively monitor cellular functions direct new ones. The challenges in creating devices, however are that they must be integrated with cells a precise kinetically controlled process device's structure its precisely structured interface then maintained during active function. Here we report ability to...
This article proposes a combined prediction method based on the Markov chain to realize precise short-term wind power predictions. First, three chaotic models are proposed for of time series, which can master physical principles in processes and guide long-term prediction. Then, considering mechanism switching between different via chain, model is constructed. Finally, industrial data from Chinese farm were taken as study case, results validated feasibility superiority method.
ABSTRACT Techniques from structural DNA nanotechnology make it possible to assemble complex 3-dimensional nanostructures with virtually arbitrary control over their sizes, shapes and features at length scales of 3–100 nm, providing a flexible means for constructing nanoscale devices machines. Here, we micron-length nanotubes assess performance as pipes controlled ion transport. grow via assembly tiles seed pore, 12-helix origami cylinder functionalized cholesterol, form nanotube channel. The...
Abstract Designed and engineered protein DNA nanopores can sense characterize single molecules control transmembrane transport of molecular species. However, designed biomolecular pores are less than 100 nm in length used primarily for across lipid membranes. Nanochannels that span longer distances could be as conduits between non-adjacent compartments or cells. Here, we design microns-long, 7 diameter nanochannels small traverse according to the laws continuum diffusion. Binding origami...