A5043148907- Optical Imaging and Spectroscopy Techniques
- Photoacoustic and Ultrasonic Imaging
- Spectroscopy Techniques in Biomedical and Chemical Research
- Ultrasound and Hyperthermia Applications
- Photodynamic Therapy Research Studies
- Plant Surface Properties and Treatments
- Greenhouse Technology and Climate Control
- Tree Root and Stability Studies
- Advanced Radiotherapy Techniques
- Laser Applications in Dentistry and Medicine
Lund University
2023-2025
SpectraCure (Sweden)
2023-2025
Politecnico di Milano
2021
SignificanceThe spatial distribution of the photosensitizing drug concentration is an important parameter for predicting photodynamic therapy (PDT) outcome. Current diffuse fluorescence tomography methods lack accuracy in quantifying concentration. The development accurate monitoring temporal evolution tissue can advance real-time light dosimetry PDT tumors, leading to better treatment outcomes.AimWe develop optical based on interstitial measurements accurately reconstruct fluorescent drugs...
Phantoms simultaneously mimicking anatomical and optical properties of real tissues can play a pivotal role for improving dosimetry algorithms. The aim the paper is to design develop hybrid phantom model that builds up on strengths solid liquid phantoms various structures prostate cancer photodynamic therapy (PDT) validation. comprises photosensitizer-embedded gelatin lesion within Intralipid shape surrounded by silicone outer shell. was well characterized properties. final assembled also...
Incorrect pesticide use in plant protection often involve a risk to the health of operators and consumers can have negative impacts on environment crops. The application artificial intelligence techniques help reduction volume sprayed, decreasing these impacts. In Italy, production ready-to-eat salad greenhouses requires usually from 8 12 treatments per year. Moreover, inappropriate sprayers are frequently used, being originally designed for open-field operations. To solve this problem,...
Diffuse Raman spectroscopy (DIRS) extends the high chemical specificity of scattering to in-depth investigation thick biological tissues. We present here a novel approach for time-domain diffuse (TD-DIRS) based on single-pixel detector and digital micromirror device (DMD) within an imaging spectrometer wavelength encoding. This overcomes intrinsic complexity cost detection arrays with ps-resolving time capability. Unlike spatially offset (SORS) or frequency (FORS), TD-DIRS exploits...
Bioresorbable photonic implants are emerging as potential material choice for interstitial theranostic and monitoring applications. They gradually dissolve within the physiological environment in a clinically relevant period, eliminating need extraction surgeries. In present study, we tested suitability of in-house fabricated bioresorbable optical fibres based on calcium phosphate (CaP) glass diffuse correlation spectroscopic (DCS) fluorescence tomographic (DFT) The results represent fibers...
We derive and validate an analytical model that describes the migration of Raman scattered photons in two-layer diffusive media, based on diffusion equation time domain. The is derived under a heuristic approximation background optical properties are identical excitation emission wavelengths. Methods for reconstruction spectra have been developed, tested computer simulations validated tissue-mimicking phantom measurements data. Effects different parameters were studied simulations, showing...
We present and derive an analytical model that describes the migration of Raman scattered photons in two-layer diffusive media, based on diffusion equation time domain. The is derived under a heuristic approximation background optical properties are identical excitation emission wavelengths. Methods for reconstruction spectra have been developed, tested computer simulations validated tissue-mimicking phantom measurements data. Effects different parameters were studied simulations, showing...
We present and derive an analytical model that describes the migration of Raman scattered photons in two-layer diffusive media, based on diffusion equation time domain. The is derived under a heuristic approximation background optical properties are identical excitation emission wavelengths. Methods for reconstruction spectra have been developed, tested computer simulations validated tissue-mimicking phantom measurements data. Effects different parameters were studied simulations, showing...
Phantoms simultaneously mimicking anatomical and optical properties of real tissues can play a pivotal role for improving dosimetry algorithms. The aim the paper is to design develop hybrid phantom model that builds up on strengths solid liquid phantoms various structures prostate cancer photodynamic therapy (PDT) validation. comprises photosensitizer-embedded gelatin lesion within intralipid shape surrounded by silicone outer shell. was well characterized properties. final assembled also...
Phantoms simultaneously mimicking anatomical and optical properties of real tissues can play a pivotal role for improving dosimetry algorithms. The aim the paper is to design develop hybrid phantom model that builds up on strengths solid liquid phantoms various structures prostate cancer photodynamic therapy (PDT) validation. comprises photosensitizer-embedded gelatin lesion within intralipid shape surrounded by silicone outer shell. was well characterized properties. final assembled also...
We propose a novel analytical time-domain model for migration of Raman scattered photons in inhomogeneous two-layer diffusive media. Based on this model, the methods reconstruction spectra two layers are developed, tested simulations and validated phantom measurements data.