A5008139128- Metal complexes synthesis and properties
- Synthesis and biological activity
- Advanced Nanomaterials in Catalysis
- TiO2 Photocatalysis and Solar Cells
- X-ray Diffraction in Crystallography
- Advanced Photocatalysis Techniques
- Crystallization and Solubility Studies
- Synthesis and Biological Evaluation
- Nanoplatforms for cancer theranostics
- Microbial Metabolic Engineering and Bioproduction
- Microplastics and Plastic Pollution
- Synthesis and Characterization of Heterocyclic Compounds
- Graphene and Nanomaterials Applications
- Luminescence and Fluorescent Materials
- Antimicrobial Peptides and Activities
- Ferrocene Chemistry and Applications
- Marine and coastal ecosystems
- Photodynamic Therapy Research Studies
- Aquaculture disease management and microbiota
- Aquatic Ecosystems and Phytoplankton Dynamics
- Protein Hydrolysis and Bioactive Peptides
- Click Chemistry and Applications
- Recycling and Waste Management Techniques
- Enzyme Catalysis and Immobilization
- Enzyme Structure and Function
Pukyong National University
2019-2025
Korea Research Institute of Chemical Technology
2023
Abstract Deaths caused by cancer and bacterial infection necessitate the development of new potential compounds with desired properties that could circumvent problem chemo resistant bacteria. The present review focuses on potent transition metal complexes tunable activity against cells multidrug‐resistant Mechanistically, induce cell accumulation in G2 phase, as well DNA breakage endoplasmic reticulum stress inhibit growth cancerous cells. Parallelly, redox‐active, cationic oxidative...
The development of heavy-atom-free photosensitizers (PSs) for photodynamic therapy (PDT) has encountered significant challenges in achieving simultaneous high fluorescence emission and reactive oxygen species (ROS) generation. Moreover, the limited water solubility these PSs imposes further limitations on their biomedical applications. To overcome obstacles, this study presents a molecular design strategy employing hydrophilic based imidazolium salts. photophysical properties were...
In this study, we developed a label-free biosensor based on aptamer-modified multi-walled carbon nanotube extended gate field-effect transistor (MWCNT-EG-FET) for easy and selective detection of microcystin-LR (MC-LR), prominent cyanotoxin associated with liver damage, bleeding, necrosis. EG-FET had two parts: MOSFET an extended-gate Au/SiO2 electrode, which serves as the sensitive membrane. A custom-designed DNA oligonucleotide (5-NH2-C6-AN6) was used MC-LR-targeting aptamer (MCTA). MWCNTs...
Cold-active enzymes increase their catalytic efficiency at low-temperature, introducing structural flexibility or near the active sites. Inevitably, this feat seems to be accompanied by lower thermal stability. These characteristics have made cold-active into attractive targets for industrial applications, since they could reduce energy cost in reaction, attenuate side-reactions, and simply inactivated. In addition, increased result broad substrate specificity various non-native substrates,...
Interest in protein engineering for the enzymatic production of valuable products, such as pharmaceutical compounds and biofuels, is growing rapidly. The cold-active acetyl xylan esterase from Paenibacillus sp. (PbAcE) presents unusually broad substrate specificity. Here, we engineered a hydrophobic substrate-binding pocket to enable accommodation relatively large alcohol substrates, linalyl acetate α-terpinyl acetate. To identify candidate residues engineering, performed covalent docking...
Abstract In this study, we synthesized the cobalt(II) chelation free complexes ( 1 – 3 ) with general formula of [CoCl 2 L ] containing monodentate ligands (L=2‐methylbenzimidazole L1 ), 2‐methylbenzoxazole L2 and 2‐methylbenzothiazole L3 fully characterized by UV‐vis, FT‐IR spectroscopy, crystal structures were determined X‐ray crystallography. Complexes showed substantial antibacterial activity against tested bacteria. more active S. aureus Minimum Inhibitory concentration (MIC) value 12.5...
In this work, solar-light-active copper–vanadium oxide (Cu-VO) was synthesized by a simple microwave method and characterized FESEM, EDS, XRD, XPS, UV–Vis/near-infrared (NIR), FT-IR spectroscopy. Antialgal dye degradation activities of Cu-VO were investigated against Microcystis aeruginosa methylene blue (MB), respectively. The mechanism action examined regarding the production hydroxyl radical (·OH) in medium intracellular reactive oxygen species (ROS) M. aeruginosa. FESEM XRD analyses...
Liver-expressed antimicrobial peptides (LEAPs) are cysteine-containing cationic peptides. LEAP-1 and LEAP-2 eight- four-cysteine containing found in animals, respectively. is widely known as antibacterial peptide involved the innate immunity of fish, but roles Antarctic fish species unknown. In present study, we synthesized characterized novel LEAPs with four eight cysteine residues, derived from notothenioid (Dissostichus mawsoni) eelpout (Lycodichthys dearborni). Circular dichroism...
In this study, we attempted to synthesize visible light active nano-sized photocatalysts using metal oxides such as zinc oxide, zirconium tungsten and strontium titanium oxide with (MoCl5)2 a dopant by the simple ball-milling method. Fourier-transform infrared spectroscopy data confirmed presence of M-O-Mo linkage (M = Zn, Zr, W, SrTi) in all molybdenum-doped (MoMOs), but only MoZnO inhibited growth bloom-forming Microcystis aeruginosa under concentration-dependent manner up 10 mg/L....
Cancer has emerged as a significant global health challenge, ranking the second leading cause of death worldwide. Moreover, cancer patients frequently experience compromised immune systems, rendering them susceptible to bacterial infections. Combining anticancer and antibacterial properties in single drug could lead improved overall treatment outcomes patient well-being. In this context, present study focused on series hydrophilic naphthoimidazolium salts with donor groups (NI-R), aiming...