A5032168106- Magnesium Alloys: Properties and Applications
- Corrosion Behavior and Inhibition
- Hydrogen Storage and Materials
- Tracheal and airway disorders
- Periodontal Regeneration and Treatments
- Bone Tissue Engineering Materials
- Aluminum Alloys Composites Properties
- Calcium Carbonate Crystallization and Inhibition
- Esophageal and GI Pathology
- Osteoarthritis Treatment and Mechanisms
- Antimicrobial Peptides and Activities
- Surface Modification and Superhydrophobicity
- Advanced biosensing and bioanalysis techniques
- MXene and MAX Phase Materials
- Invertebrate Immune Response Mechanisms
- Electrochemical Analysis and Applications
- Neonatal Health and Biochemistry
- Porphyrin Metabolism and Disorders
- Hydrogen embrittlement and corrosion behaviors in metals
- Proteoglycans and glycosaminoglycans research
- Marine Biology and Environmental Chemistry
- Polymer Surface Interaction Studies
- Insect Utilization and Effects
- Foreign Body Medical Cases
- Electrostatics and Colloid Interactions
Jiangsu Institute of Parasitic Diseases
2024
University of Pittsburgh
2016-2020
East China University of Science and Technology
2019-2020
McGowan Institute for Regenerative Medicine
2017-2020
Soochow University
2014
Zero to Three
2013
Chinese Academy of Sciences
2013
University of Science and Technology of China
2013
Magnesium alloys have been extensively studied as a novel biodegradable metallic material for cardiovascular stent application. However, the ductility limitation of magnesium alloy has key issue stents applications. In this study, two different multiphase ultrahigh Mg–Li–Zn alloys, LZ61 and LZ91, are fabricated in form extruded rods evaluated both vitro vivo. The microstructure, mechanical properties degradation well cytotoxicity. vivo degradation, tissue response, systematic toxicity mouse...
Abstract Using a zebrafish model for hepatoerythropoietic porphyria (HEP), we found new mechanism underlying heme regulation of exocrine zymogens. Zebrafish bach1b, nrf2a and mafK are all expressed in the pancreas. Overexpression bach1b knockdown result downregulation zymogens, whereas overexpression cause their upregulation. In vitro luciferase assays demonstrated that activates zymogens dosage-dependent manner, promoter activities require integral MARE (Maf Recognition Element) motif. The...
Pediatric laryngotracheal stenosis is a complex congenital or acquired airway injury that may manifest into potentially life-threatening emergency condition. Depending on the severity of obstruction, treatment often requires combination endoscopic techniques, open surgical repair, intraluminal stenting, tracheostomy. A balloon expandable biodegradable stent maintaining patency while safely degrading over time address complications and morbidity issues existing treatments providing less...
Magnesium alloys are the most widely studied biodegradable metals for vascular stent application. Two major issues with current magnesium alloy based stents their low ductility and fast corrosion rates. Several studies have validated that introduction of Li into will significantly improve while alloying Al resistance strength. In present study, we effects different amounts on Mg–Li–Al–Zn (LAZ) quaternary system. Rods were made from four LAZ alloys, namely, LAZ611, LAZ631, LAZ911, LAZ931...
Abstract Tracheal stenting currently using non‐degradable stents is commonplace for treatment of trauma, prolonged intubation related adult airway obstructions, and pediatric patients‐associated tracheal stenosis conditions. Degradable stent placement will avoid complications removal restenosis. Widespread reports exist on degradable magnesium alloys success orthopedic cardiovascular applications but none to date intra use. This research explores the use pure Mg, AZ31, Mg‐3Y assessment. In...
Optimal integration between the polyethylene terephthalate (PET) graft and host bone is a prerequisite to obtain satisfactory outcome after implantation for ligament reconstruction. Recent studies indicate that complex biosignals including immunoregulation, cell recruitment, osteogenic differentiation provided by extracellular matrix (ECM) are conducive promoting osseointegration. In present study, chondroitin sulfate (CS)/polydopamine-modified PET was developed regulate local immune...
Species of Ostreidae family are key ecosystem engineers and many them (including Crassostrea gigas C. virginica) commercially important aquaculture species. Despite similarities in their morphology ecology, these two species differ ability to defend against pathogens potentially reflecting species-specific differential specialization hemocytes on immune defense vs. biomineralization. To test this hypothesis, we investigated the expression levels biomineralization-related genes as well...
Airway obstruction conditions are relatively rarely observed in clinical settings but nevertheless, extremely challenging to handle, especially when pediatric patients. Several surgical procedures, including tracheal resection, end-to-end anastomosis, and tracheoplasty, have been developed practised of late, treat airway obstruction. However, the outcome is typically not satisfactory due restenosis that develop following surgery. Various types stents currently available for stenting ranging...
For biodegradable iron coronary stents, the major problem is low degradation rate in body environment. In this study, a new strategy was proposed to increase of vitro. The hydrion evolution intended be introduced into system rate. To realize strategy, polylactic-co-glycolic acid (PLGA) coated onto surface pure iron. process and mechanism with PLGA were investigated. results showed that exhibited higher static immersion test all along. With PLGA, oligomers could release abundant H+ which...
ABSTRACT The emergence of clinically drug-resistant malaria parasites requires the urgent development new drugs. Mosquitoes are vectors multiple pathogens and have developed resistance mechanisms against them, which often involve antimicrobial peptides (AMPs). An-cecB is an AMP malaria-transmitting mosquito genus Anopheles , we herein report its antimalarial activity Plasmodium falciparum 3D7, artemisinin-resistant strain 803, chloroquine-resistant Dd2 in vitro . We also demonstrate...
For biodegradable iron coronary stents, the major problem is low degradation rate in body environment. In this study, a new strategy was proposed to increase of vitro. The hydrion evolution intended be introduced into system rate. To realize strategy, polylactic-co-glycolic acid (PLGA) coated onto surface pure iron. process and mechanism with PLGA were investigated. results showed that exhibited higher static immersion test all along. With PLGA, oligomers could release abundant H