A5015094482- Stress Responses and Cortisol
- Neuroendocrine regulation and behavior
- Tryptophan and brain disorders
- Adipose Tissue and Metabolism
- Neuroscience and Neuropharmacology Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurotransmitter Receptor Influence on Behavior
- Cannabis and Cannabinoid Research
- Animal Behavior and Welfare Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Meat and Animal Product Quality
- Regulation of Appetite and Obesity
- Diet, Metabolism, and Disease
- Animal Nutrition and Physiology
- Effects of Environmental Stressors on Livestock
- Biochemical effects in animals
- Birth, Development, and Health
- Immune Cell Function and Interaction
- Inflammatory mediators and NSAID effects
- Immune Response and Inflammation
- Diet and metabolism studies
- Neuropeptides and Animal Physiology
- Pharmacological Effects and Assays
- Eicosanoids and Hypertension Pharmacology
- Neuroscience of respiration and sleep
University of Gdańsk
2014-2025
Institute of Agricultural and Food Biotechnology
2019-2024
Louisiana State University Health Sciences Center Shreveport
2004-2017
Louisiana State University
1995-2014
Institute of Plant Genetics, Polish Academy of Sciences
2004-2013
Polish Academy of Sciences
1984-2012
Louisiana State University Health Sciences Center New Orleans
2005-2011
Instytut Biologii Doświadczalnej im. Marcelego Nenckiego
2003
University Medical Center
1995-2000
University Hospital and Clinics
1995-2000
Corticotropin-releasing hormone (CRH) is a central regulator of the hormonal stress response, causing stimulation corticotropin and glucocorticoid secretion. CRH also widely believed to mediate stress-induced behaviors, implying broader, integrative role for in psychological response. Mice lacking gene exhibit normal behavior that specifically blocked by type 1 receptor antagonist. The other known mammalian ligand receptors urocortin. Normal CRH-deficient mice have an identical distribution...
Psychogenic stress contributes to the formation of brain pathology. Using gene expression microarrays, we analyzed hippocampal transcriptome mice subjected acute and chronic social different duration. The longest period altered highest number genes most stress-induced changes in transcription were reversible after 5 days rest. Chronic affected involved functioning vascular system (Alas2, Hbb-b1, Hba-a2, Hba-a1), injury response (Vwf, Mgp, Cfh, Fbln5, Col3a1, Ctgf) inflammation (S100a8,...
In order to better understand the effects of social stress on prefrontal cortex, we investigated gene expression in mice subjected acute and repeated encounters different duration using microarrays. The most important finding was identification hemoglobin genes (Hbb-b1, Hbb-b2, Hba-a1, Hba-a2, Beta-S) as potential markers chronic mice. Expression these progressively increased animals 8 13 days correlated with altered Mgp (Mglap), Fbln1, 1500015O10Rik (Ecrg4), SLC16A10, Mndal. Chronic also...
Alpha-hydroxy acids (AHAs) are one of the classes hydroxy being beneficial for human health. The manuscript summarizes biological properties two popular members AHAs, i.e., Mandelic Acid (MA) and Gallic (GA), with particular emphasis on antimicrobial properties. Moreover, attempts to design new derivatives improving natural AHAs by using chemical physical approach discussed.Antimicrobial MA, an arylalkyl AHA containing phenyl group attached α- carbon, GA, aromatic trihydroxybenzoic acid...
Cannabidiol (CBD), the major non-psychotropic compound of Cannabis sp., is an effective treatment for inflammatory and autoimmune diseases produces various anti-tumor effects but mechanisms its long-term actions in vivo remain unclear. We have previously shown that CBD administration (5 mg/kg) healthy rats significantly decreased lymphocyte numbers peripheral blood, involving B, T CD4+ CD8+ subsets, not natural killer (NK) cells. To examine on subsets spleen NK cellular cytotoxicity (NKCC),...