A5005950405- Neuroscience and Neuropharmacology Research
- Cannabis and Cannabinoid Research
- Memory and Neural Mechanisms
- Neurotransmitter Receptor Influence on Behavior
- Tryptophan and brain disorders
- Sleep and Wakefulness Research
- GABA and Rice Research
- Stress Responses and Cortisol
- Diet, Metabolism, and Disease
- Neuroendocrine regulation and behavior
- Photoreceptor and optogenetics research
- Neuroinflammation and Neurodegeneration Mechanisms
- Transcranial Magnetic Stimulation Studies
- Circadian rhythm and melatonin
- Cytomegalovirus and herpesvirus research
- Herpesvirus Infections and Treatments
- Neural dynamics and brain function
- Toxoplasma gondii Research Studies
- Neurogenesis and neuroplasticity mechanisms
- Vestibular and auditory disorders
- Neuroscience of respiration and sleep
Okinawa Institute of Science and Technology Graduate University
2022-2025
Universidade de São Paulo
2014-2016
Instituto de Neurociências e Comportamento
2014-2016
Universidade Federal de Minas Gerais
2010-2014
In recent years, a growing interest has been dedicated to the study of endocannabinoid system. The isolation Cannabis sativa main psychotropic compound, Δ(9)-tetrahydrocannabinol (THC), led discovery an atypical neurotransmission system that modulates release other neurotransmitters and participates in many biological processes, including cascade inflammatory responses. this context, cannabinoids have studied for their possible therapeutic properties neuroinflammatory diseases. review,...
Cannabidiol (CBD), the major non-psychotropic compound of Cannabis sp., is an effective treatment for inflammatory and autoimmune diseases produces various anti-tumor effects but mechanisms its long-term actions in vivo remain unclear. We have previously shown that CBD administration (5 mg/kg) healthy rats significantly decreased lymphocyte numbers peripheral blood, involving B, T CD4+ CD8+ subsets, not natural killer (NK) cells. To examine on subsets spleen NK cellular cytotoxicity (NKCC),...
We recently determined that the excitatory manipulation of Qrfp-expressing neurons in preoptic area hypothalamus (quiescence-inducing [Q neurons]) induced a hibernation-like hypothermic/hypometabolic state (QIH) mice. To control QIH with higher time resolution, we develop an optogenetic method using modified human opsin4 (OPN4; also known as melanopsin), G protein-coupled-receptor-type blue-light photoreceptor. C-terminally truncated OPN4 (OPN4dC) stably and reproducibly induces for at least...
OBJETIVO: Este artigo revisa o sistema endocanabinoide e as respectivas estratégias de intervenções farmacológicas. MÉTODO: Realizou-se uma revisão da literatura sobre a sua farmacologia, considerando-se artigos originais ou escritos em inglês. DISCUSSÃO: Canabinoides são um grupo compostos presentes na Cannabis Sativa (maconha), exemplo do Δ9-tetraidrocanabinol seus análogos sintéticos. Estudos seu perfil farmacológico levaram à descoberta cérebro mamíferos. é composto por pelo menos dois...
The cerebellum is more than just motor control: over the past 30 years, notion that "little brain" participates in cognitive functions and emotional response has grown to encompass social-related behaviors. Chao et al. bring light role of cerebellar vermis orchestrating a specific component social memory mice.
The use of Cannabis sativa by humans dates back several thousand years, for both its psychotomimetic and potential medicinal properties.As scientific research methods developed, the cannabinoids present in this herb were characterized, as well their complex interface with human central nervous system, provided activation specific receptors.The subsequent description an endogenous cannabinoid system mammalian brain shifted notion cannabis a recreational drug to therapeutic alternative...