The aim of this study is to evaluate the effect apigenin on inflammatory response in brain tissue Parkinson's mouse model.

The current study was designed to determine the changes of cardiac troponin I (cTnI) expression in blood and tissue during myocardial degeneration calves with foot-and-mouth disease (FMD). Seventeen crossbred presenting pathological signs for FMD confirmed by viral analysis were studied. A biochemistry panel immunohistochemistry performed on 17 diseased 7 used as controls. Creatine kinase (CK), CK-myocardial band (CK-MB), aspartate aminotransferase (AST), lactate dehydrogenase (LDH)...

Fifty canine lymphomas were classified cytomorphologically using the updated Kiel classification scheme. Aspirates of lymph nodes from dogs with lymphoma stained 5 canine-specific antibodies and 3 human-specific that cross-react lymphocytes. The antibody-stained aspirates analyzed by flow cytometry. A total 32 (64%) 50 characterized as B-cell origin 18 (36%) T-cell origin. identified in 12 females 20 males a mean age 8.35 years. 8 10 7.9 minority low-grade (6/50, 12% 4/50, 8%, respectively)....

The present study was conducted to investigate the effect of silymarin on experimental liver toxication induced by Fumonisin B₁1 (FB₁) in BALB/c mice. mice were divided into six groups (n = 15). Group 1 served as control. 2 control (100 mg/kg gavage). Groups 3 and 4 treated with FB₁ (Group 3, 1.5 FB₁, intraperitoneally; 4, 4.5 FB₁). 5 received (1.5 mg/kg) mg/kg), 6 given a higher dose (4.5 FB₁) mg/kg). Silymarin treatment significantly decreased (p < 0.0001) apoptotic rate. FB1...

Uterine tissue was collected from bitches after ovariohysterectomy at different times ovulation. Samples were assigned to four groups: metestrous non-pregnant, day 10-12, n = 4; pre-implantation, 9; post-implantation, 18-25, 13; mid-gestation, 30-40, 7. RT-qPCR detection performed for kiss1 and the G protein-coupled receptor 54 (GPR54, specific kisspeptin). In addition, immunohistochemistry of kisspeptin-10 (KP-10), GPR54, as well pan-cytokeratin vimentin. The latter two included...

Abstract The main challenges in treating cancer using chemotherapeutics are insufficient dose at the target site and development of drug resistance, while higher doses can induce side effects by damaging nontarget tissues. Combinatorial therapy may overcome these limitations permitting lower more specific targeting, thereby mitigating resistance effects. Recent reports indicate that nonsteroidal anti‐inflammatory drugs (NSAIDs) have anticancer potential be used together with conventional to...

Summary In animals and man, some forms of cutaneous papillomas are caused by papillomaviruses. Twelve different genotypes bovine papillomavirus (BPV) have been identified. BPV-1 through BPV-12 all strictly species-specific. BPV-2 associated with fibropapillomas in cattle; these tumors formed excessive proliferation virus-infected dermal fibroblasts epidermal keratinocytes. the present study well known diagnostic procedures including histopathological, immunohistochemical molecular methods...

White muscle disease (WMD) is a world-wide nutritional of all animal species characterised by degeneration skeletal and cardiac muscles. In the present study we determined troponin I (cTnI) inducible nitric oxide synthase (iNOS) expression in hearts lambs with WMD (n = 15). Eight clinically healthy served as control. Creatine kinase (CK), creatine MB (CK-MB), aspartate aminotransferase (AST), lactate dehydrogenase (LDH) activities were analysed for both groups. cTnI levels measured...

Six colostrum‐deprived, hysterotomy‐derived calves were maintained under sterile conditions and fed a milk replacer diet. At five days of age, the dosed orally with 10 9 cfu Escherichia coli 0157: H7 strain A84. They killed after, one, two, six, 12 24 days, samples taken for bacteriological pathological examination. The sixth uninfected control calf was at seven age matched comparison. animals remained normal throughout observation period. Bacteriological data indicated heavy bacterial load...

Summary Basal cell adenocarcinoma of the salivary gland is described in a cat and two dogs; tumour tissue was characterized by cords islands epithelial cells with distinct basal layer. The tumours were stained various immunohistochemical methods. In addition to positive staining cytokeratin 14 pancytokeratin (CKs 5, 6, 8, 17 19), there also Jack bean agglutinin A (ConA) soya (SBA); this occurs many other types feature normal acinar cells. one dog SBA. This first report domestic animals;...

Objective— To evaluate the feasibility of urethroplasty using a free fascia lata (FL) graft in dog. Study Design— In vivo experimental study. Animals— Mixed‐breed dogs (n=14). Methods— Half circumference urethra, ∼1.5 cm long, was excised 14 male to induce urethral defect. FL (∼2 × 2 cm) harvested from lateral thigh sutured urethra 3‐0 polyglactin 910 continuous pattern. Dogs were monitored daily for bladder distention and had catheters until normal voiding observed. On day 60, each dog...

Commercial probiotic capsules that contain bacteria, kefir, koumiss and yogurt beneficial microorganisms affect cholesterol levels immune response, are used for treatment of some diseases. We investigated using immunohistochemistry the effects koumiss, a commercial formulation on expression peroxisome proliferator-activated receptor-α (PPARα) receptor-β/δ (PPAR-β/δ), which members nuclear steroid hormone receptor superfamily in mouse kidney. Mice were assigned to five groups: group 1,...

We investigated the expression of microtubule-associated protein 1 light chain 3 (LC3) in cerebellums dogs infected with canine distemper virus (CDV) using immunohistochemistry to detect autophagy. The 20 CDV were used. Specimens showing demyelination white matter considered have an acute infection, whereas specimens signs severe perivascular cuffing and classified as having chronic CDV. Cerebellar sections immunostained LC3 antibodies. cytoplasm Purkinje cells, granular layer motor neurons...

Benign connective tumours of the canine salivary glands are rare. This report describes lipomatous infiltration parotid or submandibular in seven dogs which were enlarged as a result by fat cells; they appeared to have been successfully treated local excision. The precise cause is unclear but different causes similar lesions humans discussed.