A5011493769- Microbial Natural Products and Biosynthesis
- Fungal Biology and Applications
- Marine Sponges and Natural Products
- Plant Pathogens and Fungal Diseases
- Mycotoxins in Agriculture and Food
- Phytochemical compounds biological activities
- Plant-Microbe Interactions and Immunity
- Natural product bioactivities and synthesis
- Synthetic Organic Chemistry Methods
- Chemical synthesis and alkaloids
- Plant biochemistry and biosynthesis
- Essential Oils and Antimicrobial Activity
- Plant and fungal interactions
- Fungal and yeast genetics research
- Synthesis and Biological Activity
- Phytochemistry and Biological Activities
- Phytochemicals and Antioxidant Activities
- Microbial Metabolism and Applications
- Alkaloids: synthesis and pharmacology
- Insect Pest Control Strategies
- CRISPR and Genetic Engineering
- Phytochemical Studies and Bioactivities
- Genomics and Phylogenetic Studies
- Pharmacological Effects of Natural Compounds
- Traditional and Medicinal Uses of Annonaceae
China Agricultural University
2016-2025
Sanya University
2025
Institute of Plant Protection
2016-2025
Ministry of Agriculture and Rural Affairs
2020
State Council of the People's Republic of China
2020
Heinrich Heine University Düsseldorf
2012-2015
University of Benin
2015
Beijing University of Agriculture
2015
Institut für Biotechnologie und Wirkstoff-Forschung
2014
Peking University
2010-2013
Coculturing the fungal endophyte Fusarium tricinctum with bacterium Bacillus subtilis 168 trpC2 on solid rice medium resulted in an up to 78-fold increase accumulation constitutively present secondary metabolites that included lateropyrone (5), cyclic depsipeptides of enniatin type (6-8), and lipopeptide fusaristatin A (9). In addition, four compounds (1-4) including (-)-citreoisocoumarin (2) as well three new natural products (1, 3, 4) were not discrete bacterial controls only detected...
A chemical investigation of the endophytic fungus Epicoccum nigrum isolated from leaves Mentha suaveolens collected in Morocco resulted isolation five new polyketides, epicocconigrones and B (1 2), 3-methoxyepicoccone (3), (4), 2,3,4-trihydroxy-6-(methoxymethyl)-5-methylbenzaldehyde (5), together with known compounds (6-10). The structures were unambiguously determined by extensive analysis 1D 2D NMR mass spectroscopic data. Compounds 1 10 showed potent inhibition at least 15 protein kinases...
The endophytic fungus Penicillium citrinum was isolated from a fresh stem of the Moroccan plant Ceratonia siliqua. Extracts P. grown on rice and white bean media yielded five new compounds, namely, citriquinochroman (1), tanzawaic acids G H (2 3), 6-methylcurvulinic acid (4), 8-methoxy-3,5-dimethylisoquinolin-6-ol (5), one natural product, 1,2,3,11b-tetrahydroquinolactacide (6), which had previously been described as synthetic compound. In addition, 13 known compounds including seven...
Ustilaginoidins were bis-naphtho-γ-pyrones mycotoxins possessing an aR configuration of the chiral axis previously reported from false smut balls rice infected by fungal pathogen Ustilaginoidea virens. To investigate chemical diversity these metabolites and their bioactivities, we fermented this fungus on solid media, which afforded isolation 13 ustilaginoidins, including seven new compounds, namely ustilaginoidins K–P, 1–6, E1, 7, together with known A, 8, D, 9, E, 10, F, 11, G, 12,...
Chemical investigation of the EtOAc extract endophytic fungus Bionectria ochroleuca, isolated from inner leaf tissues plant Sonneratia caseolaris (Sonneratiaceae) Hainan island (China), yielded two new peptides, pullularins E and F (1 2) together with three known compounds (3–5). The structures were unambiguously determined on basis one- two-dimensional NMR spectroscopy as well by high-resolution mass spectrometry. absolute configurations amino acids HPLC analysis acid hydrolysates using...
Ustiloxins were cyclopeptide mycotoxins from rice false smut balls (FSBs) that formed in spikelets infected by the fungal pathogen Ustilaginoidea virens. To investigate chemical diversity of these metabolites and their bioactivities, one new cyclopeptide, ustiloxin G (1), together with four known congeners-ustiloxins A (2), B (3), D (4), F (5)-were isolated water extract FSBs. Their structures elucidated analyses physical spectroscopic data, including ultraviolet spectrometry (UV), infrared...
Ustilaginoidins are a class of bis-naphtho-γ-pyrones, typically produced by Villosiclava virens, the pathogen rice false smut (RFS), which has been one most destructive fungal diseases. Previously, we found that ustilaginoidins identified from culture V. virens on medium were less polar than those reported RFS balls in general. In this study, reinvestigated high-performance liquid chromatography with diode array detection and high-resolution mass spectrometry (HPLC-DAD-HRMS) profile ethyl...
Nine new spirobisnaphthalenes, palmarumycins B1-B9 (1-9), along with 13 known compounds (10-22), were isolated from cultures of the fungus Berkleasmium sp., an endophyte medicinal plant Dioscorea zingiberensis C. H. Wright. The structures elucidated by analysis 1D and 2D NMR HRESIMS spectra comparison compounds. Compounds 7-9 contain uncommon 2,3-dihydro-1H-inden-1-one unit. All evaluated for their antibacterial activities against Bacillus subtilis, Staphylococcus hemolyticus, Agrobacterium...
Six new dibenzo-α-pyrones, rhizopycnolides A (1) and B (2) rhizopycnins A–D (3–6), together with eight known congeners (7–14), were isolated from the endophytic fungus Rhizopycnis vagum Nitaf22 obtained Nicotiana tabacum. The structures of compounds unambiguously elucidated using NMR, HRESIMS, TDDFT ECD calculation, X-ray crystallography data. Rhizopycnolides feature an uncommon γ-butyrolactone-fused dibenzo-α-pyrone tetracyclic skeleton (6/6/6/5), while rhizopycnin (4) was first amino group...
The EtOAc extract of the liquid fermentation Alternaria sp. Samif01, an endophytic fungus obtained from Salvia miltiorrhiza Bunge, showed antibacterial activity against several tested bacterial pathogens. Fractionation this led to isolation seven dibenzo-α-pyrones (1–7), including one new compound, 2-acetoxy-2-epi-altenuene (1) and natural product, 3-epi-dihydroaltenuene A (2). structures metabolites were elucidated by comprehensive analysis spectroscopic data (1D, 2D) NMR HRESIMS, while...