About
Contact & Profiles
A5048672340
Research Areas
- Immune Cell Function and Interaction
- Adipokines, Inflammation, and Metabolic Diseases
- IL-33, ST2, and ILC Pathways
- SARS-CoV-2 and COVID-19 Research
- vaccines and immunoinformatics approaches
- COVID-19 Clinical Research Studies
Universitätsklinikum Erlangen
2022
Obesity has become a major health problem in the industrialized world. Immune regulation plays an important role adipose tissue homeostasis; however, initial events that shift balance from noninflammatory homeostatic environment toward inflammation leading to obesity are poorly understood. Here, we report for costimulatory molecule programmed death-ligand 1 (PD-L1) limitation of diet-induced obesity. Functional ablation PD-L1 on dendritic cells (DCs) using conditional knockout mice increased...
10.1126/scitranslmed.abj6879
article
EN
Science Translational Medicine
2022-03-09
10.1016/j.ebiom.2022.104294
article
EN
cc-by-nc-nd
EBioMedicine
2022-10-04
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