A5025563363- Fullerene Chemistry and Applications
- Graphene and Nanomaterials Applications
- Nanoparticles: synthesis and applications
- Carbon Nanotubes in Composites
- Chemotherapy-induced cardiotoxicity and mitigation
- Diamond and Carbon-based Materials Research
- Immune Response and Inflammation
- Liver Disease Diagnosis and Treatment
- Boron and Carbon Nanomaterials Research
- Alcohol Consumption and Health Effects
- Carbon and Quantum Dots Applications
- Endoplasmic Reticulum Stress and Disease
- Nanoparticle-Based Drug Delivery
- Ferroptosis and cancer prognosis
- Fatty Acid Research and Health
- GDF15 and Related Biomarkers
- Diet, Metabolism, and Disease
- Polymer Nanocomposite Synthesis and Irradiation
- Paraoxonase enzyme and polymorphisms
- ATP Synthase and ATPases Research
University of Belgrade
2013-2025
Vinča Institute of Nuclear Sciences
2014
This review describes the chemical synthesis of polar polyhydroxylated fullerene C 60 derivatives, fullerenols (OH) n , 2 ≤ 44, H z O x y and polyanion 15 (ONa) 9 ranging from very first synthetic methods up to some contemporary approaches separation. It also provides basic information about physical characteristics fullerenols. With increasing number hydroxyl groups, water solubility increases as well. Fullerenols both in biological media build nanoparticles different dimensions stability....
Background/Objectives: Dietary lifestyle, particularly the intake of fatty acids (FAs), may be useful in alleviating key pathogenic processes multiple sclerosis (MS); however, data are still scarce, with regard to course disease. Therefore, objectives this study were investigate erythrocyte profile FAs patients relapsing-remitting (RR)MS and progressive (P)MS, examine whether dietary supplementation n-3 PUFAs could influence FA profile, according Methods: The was determined erythrocytes by...
Fullerenol as a promising intracellular targeting carrier for the efficient delivery of antitumor drugs into tumor cells.
Fullerenes are molecules that, due to their unique structure, have very specific chemical properties which offer them wide array of applications in nanomedicine. The most prominent protection from radiation‐induced injury, neuroprotection, drug and gene delivery, anticancer therapy, adjuvant within different treatments, photosensitizing, sonosensitizing, bone reparation, biosensing. However, it is crucial importance be elucidated how fullerenes immunomodulate human system defense. In...
Fullerenol (C60(OH)24) is present in aqueous solutions the form of polyanion nanoparticles with particles' size distribution within range from 15 to 42 nm. In this research it assumed that these features could enable fullerenol (FNPs) bind positively charged molecules like doxorubicin (DOX) and serve as drug carriers. Considering this, fullerenol/doxorubicin nanocomposite (FNP/DOX) formed characterized by ultra-performance liquid chromatography tandem mass spectrometry, dynamic light...
Fullerenol (C60(OH)24) nanoparticles (FNP) have a significant role in biomedical research due to their numerous biological activities, some of which are cytoprotective and antioxidative properties. The aim this study was measure distribution fullerenol zeta potential cell medium RPMI 1640 with 10% fetal bovine serum (FBS) investigate the influence FNP on Chinese hamster ovary cells (CHO-K1) survival, as well determine activity three enzymes: superoxide-dismutase, glutathione-reductase...
Cardioprotective effects of fullerenol C60(OH)24 nanoparticles (FNP) were investigated in pigs after a single treatment with doxorubicin (DOX). Semithin and ultrathin sections myocardial tissue routinely prepared for transmission electron microscopy analyzed. Extensive intracellular damage was confirmed cardiomyocytes DOX-treated animals. By means ultrastructural analysis, certain degree parenchymal degeneration even animals treated FNP alone, including both the oral intraperitoneal...
Fullerenols are polyhydroxylated, water soluble derivatives of fullerene C60, with potential application in medicine as diagnostic agents, antioxidants or nano drug carriers. This paper describes synthesis and physical characterization a new nanocomposite hydroxyapatite/fullerenol. Surface the hydroxyapatite/fullerenol is inhomogeneous diameter particles range from 100 nm to 350 nm. The ζ this ten times lower when compared hydroxyapatite. phosphate groups hydroxyapatite prone forming...