Justin P. McWilliams

ORCID: 0000-0001-8027-0112
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About
Contact & Profiles
Research Areas
  • Vascular Anomalies and Treatments
  • Liver Disease Diagnosis and Treatment
  • Liver Disease and Transplantation
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Tracheal and airway disorders
  • Prostate Cancer Diagnosis and Treatment
  • Urinary Bladder and Prostate Research
  • Organ Transplantation Techniques and Outcomes
  • Central Venous Catheters and Hemodialysis
  • Radiation Dose and Imaging
  • Venous Thromboembolism Diagnosis and Management
  • Vascular Malformations and Hemangiomas
  • Pulmonary Hypertension Research and Treatments
  • Vascular Procedures and Complications
  • Radiology practices and education
  • Vascular anomalies and interventions
  • Advanced X-ray and CT Imaging
  • Pelvic and Acetabular Injuries
  • Sharing Economy and Platforms
  • Hormonal and reproductive studies
  • Total Knee Arthroplasty Outcomes
  • Urologic and reproductive health conditions
  • Medical Imaging and Pathology Studies
  • Knee injuries and reconstruction techniques
  • Coronary Interventions and Diagnostics

University of California, Los Angeles
2016-2025

UCLA Health
2013-2024

University Medical Centre Mannheim
2024

UCLA Jonsson Comprehensive Cancer Center
2024

UCLA Medical Center
2014-2023

Ronald Reagan UCLA Medical Center
2010-2023

Olive View-UCLA Medical Center
2021

University of California System
2021

Society of Interventional Radiology
2016

Creative Research Enterprises (United States)
2016

Description: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease with estimated prevalence of 1 in 5000 that characterized by the presence vascular malformations (VMs). These result chronic bleeding, acute hemorrhage, and complications from shunting through VMs. The goal Second International HHT Guidelines process was to develop evidence-based consensus guidelines for management prevention HHT-related symptoms complications. Methods: were developed using AGREE II...

10.7326/m20-1443 article EN Annals of Internal Medicine 2020-09-07

Dual-Energy CT for the Assessment of Contrast Material Distribution in Pulmonary ParenchymaSven F. Thieme1, Thorsten R. C. Johnson1, Christopher Lee2, Justin McWilliams3, Christoph Becker1, Maximilian Reiser1 and Konstantin Nikolaou1Audio Available | Share

10.2214/ajr.08.1653 article EN American Journal of Roentgenology 2009-06-19

In Brief Objectives: To evaluate the rate, effect, and predictive factors of a complete pathologic response (cPR) in patients with hepatocellular carcinoma (HCC) undergoing locoregional therapy (LRT) before liver transplantation (LT). Background: Eligible HCC receive equal model for end-stage disease prioritization, despite variable risks tumor progression, waitlist dropout, posttransplant recurrence. Pretransplant LRT mitigates these by inducing necrosis. Methods: Comparisons were made...

10.1097/sla.0000000000001384 article EN Annals of Surgery 2015-08-08

Hereditary hemorrhagic telangiectasia (HHT, Osler-Weber-Rendu disease) is a rare multisystem vascular disorder causing chronic gastrointestinal bleeding, epistaxis, and severe anemia. Bevacizumab, an anti-vascular endothelial growth factor antibody, may be effective to treat bleeding in HHT. This international, multicenter, retrospective study evaluated the use of systemic bevacizumab HHT-associated anemia at 12 HHT treatment centers. Hemoglobin, epistaxis severity score, red cell units...

10.3324/haematol.2020.261859 article EN cc-by-nc Haematologica 2020-07-16

To describe the technical feasibility, safety, and clinical outcomes of coil-assisted retrograde transvenous obliteration (CARTO) in treating portal hypertensive non-esophageal variceal hemorrhage.From October 2012 to December 2013, 20 patients who received CARTO for treatment bleeding were retrospectively evaluated. All had at least 6-month follow-up. detachable coils placed occlude efferent shunt gelfoam embolization achieve complete thrombosis/obliteration varices. Technical success,...

10.1038/ctg.2014.12 article EN cc-by-nc-nd Clinical and Translational Gastroenterology 2014-10-01

In a long-term (10-year) study of radiofrequency ablation (RFA) hepatocellular carcinoma (HCC) as bridging therapy in patients listed for orthotopic liver transplantation (LT), we evaluated the impact RFA on waiting list dropout rate, post-LT tumor recurrence, and intention-to-treat, disease-specific survival (DSS). From March 2004 to October 2014, was performed initial stand-alone bridge LT 121 (men/women ratio, 83:38; mean age, 60.0 years) with 156 de novo HCCs (mean size, 2.4 cm)....

10.1002/hep.29098 article EN cc-by Hepatology 2017-02-07

Abstract Pazopanib (Votrient) is an orally administered tyrosine kinase inhibitor that blocks VEGF receptors potentially serving as anti-angiogenic treatment for hereditary hemorrhagic telangiectasia (HHT). We report a prospective, multi-center, open-label, dose-escalating study [50 mg, 100 200 and 400 mg], designed proof-of-concept to demonstrate efficacy of pazopanib on HHT-related bleeding, measure safety. Patients, recruited at 5 HHT Centers, required ≥ 2 Curacao criteria AND [anemia OR...

10.1007/s10456-018-9646-1 article EN cc-by Angiogenesis 2018-09-06

<h3>Importance</h3> Epistaxis is a major factor negatively affecting quality of life in patients with hereditary hemorrhagic telangiectasia (HHT; also known as Osler-Weber-Rendu disease). Optimal treatment for HHT-related epistaxis uncertain. <h3>Objective</h3> To determine whether topical therapy any 3 drugs differing mechanisms action effective reducing epistaxis. <h3>Design, Setting, and Participants</h3> The North American Study HHT was double-blind, placebo-controlled randomized...

10.1001/jama.2016.11724 article EN JAMA 2016-09-06

Total contact casting is the current recommended treatment for Wagner Stage 1 and 2 neuropathic plantar ulcers. The rationale this includes equalization of foot pressures generalized unweighting through a total fit at calf. requires meticulous technique multiple cast applications to avoid complications before ulcer healing. An alternative use prefabricated brace designed maintain fit. This study compares pressure metrics in standardized shoe (SS), (TCC), pneumatic walking (PPWB). Five...

10.1177/107110079701800106 article EN Foot & Ankle International 1997-01-01

Most posterior cruciate ligament reconstruction techniques use a tibial bone tunnel, which results in an acute bend the graft as it passes over portion of plateau.The inlay technique will result lower pretensions, less laxity, and stretch-out after cyclic loading.Controlled laboratory study.Graft pretensions necessary to restore normal laxity at 90 degrees knee flexion (laxity match pretension) anteroposterior laxities five angles were recorded 12 fresh-frozen specimens with bone-patellar...

10.1177/03635465020300030201 article EN The American Journal of Sports Medicine 2002-05-01

Background and Purpose— Hereditary hemorrhagic telangiectasia (HHT) is a systemic disease characterized by mucocutaneous telangiectasias, epistaxis, arteriovenous malformations (AVMs). Intracranial hemorrhage (ICH) rates in this population are not well described. We report ICH characteristics HHT patients with brain AVMs (HHT-BAVMs). Methods— studied the first 153 HHT-BAVM follow-up data enrolled Brain Vascular Malformation Consortium Project. estimated after BAVM diagnosis. Results— The...

10.1161/strokeaha.114.007367 article EN Stroke 2015-04-10

Background: The tibial inlay technique of reconstruction the posterior cruciate ligament offers potential advantages over conventional transtibial tunnel technique, particularly with regard to graft force levels that develop a functional range knee flexion. Abnormally high forces generated during rehabilitation activities could lead stretch-out critical early healing period. purpose this study was compare between these two techniques and in native ligament. Methods: A load cell installed at...

10.2106/00004623-200206000-00007 article EN Journal of Bone and Joint Surgery 2002-06-01

To investigate the usefulness of minimal ablative margin (MAM) control by intra-procedural contrast-enhanced CT (CECT) in microwave ablation (MWA) liver tumors.A total 334 consecutive tumors (240 hepatocellular carcinomas [HCCs] and 94 colorectal metastases [CRLMs]) 172 patients treated with percutaneous MWA were retrospectively included. MAM each tumor was assessed after expected completion using CECT, allowing within-session additional to any potentially insufficient margin. On immediate...

10.1007/s00330-022-08723-5 article EN cc-by European Radiology 2022-04-07

Background Prostatic artery embolization (PAE) is a safe, minimally invasive angiographic procedure that effectively treats benign prostatic hyperplasia; however, PAE-related patient radiation exposure and associated risks are not completely understood. Purpose To quantify dose assess radiation-related adverse events in patients who underwent PAE at multiple centers. Materials Methods This retrospective study included undergoing for any indication performed by experienced operators 10...

10.1148/radiol.231877 article EN Radiology 2024-03-01

To evaluate the safety and efficacy of two different methods proximal cystic artery embolization in patients undergoing yttrium-90 radioembolization.Forty-six had performed immediately before radioembolization, either by using Gelfoam pledgets (n = 35) or coils 11). Clinical symptomatology during admission angiographic findings at 1-month follow-up were retrospectively reviewed. Rates collateralization recanalization compared, as well frequency postprocedural abdominal pain need for...

10.1007/s00270-010-0021-x article EN cc-by-nc CardioVascular and Interventional Radiology 2010-11-09

Overt hepatic encephalopathy (OHE) is a serious complication of liver dysfunction, which associated with severe morbidity/mortality and healthcare resource utilization. OHE can be medically refractory due to spontaneous portosystemic shunts (SPSSs) therefore new treatment option for these SPSSs critical.This retrospective study 43 patients OHE, who underwent CARTO (Coil-Assisted Retrograde Transvenous Obliteration) procedures between June 2012 October 2016. The patient demographic...

10.1038/s41395-018-0109-5 article EN The American Journal of Gastroenterology 2018-06-12
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