A5020838398- Research on Leishmaniasis Studies
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Vasculitis and related conditions
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Dermatological diseases and infestations
- Zoonotic diseases and public health
- Vector-Borne Animal Diseases
- Sarcoidosis and Beryllium Toxicity Research
- Toxin Mechanisms and Immunotoxins
- Iron Metabolism and Disorders
- Vector-borne infectious diseases
- Leptospirosis research and findings
- Malaria Research and Control
- Insect Pest Control Strategies
- Paraoxonase enzyme and polymorphisms
- Plant Virus Research Studies
Shahid Beheshti University of Medical Sciences
2014-2024
Tehran University of Medical Sciences
2024
Phlebotomine sandflies are vectors of a large variety arboviruses, mostly in the genus Phlebovirus. Many were discovered during last decade, but only partially sequenced because extremely high genetic diversity. Next-Generation sequencing (NGS) is key tool to achieve rapid these viruses. Here we present results obtained with custom-made automated platform for throughput processing (HTP) field-trapped sandflies. The aim an integrated approach discover new/existing viruses vectored by...
Phlebotomine sandflies are vectors of phleboviruses that cause sandfly fever or meningitis with significant implications for public health. Although several strains these viruses had been isolated in Iran the late 1970's, there was no recent data about present situation at outset this study. Entomological investigations performed 2009 and 2011 collected 4,770 from 10 different regions. Based on morphological identification, they were sorted into 315 pools according to species, sex, trapping...
Leishmaniasis refers to a disease with wide range of manifestations; and there are three main forms disease, cutaneous, mucocutaneous, visceral. is one the diseases protozoan agent which vector-borne. Visceral leishmaniasis (VL) most severe form that can be fiercely life-threatening if left untreated. VL caused by members Leishmania donovani complex, in Iran, infantum considered primary causative VL, resulting zoonotic VL. The two goals our work, followed prior sero-epidemiological...
Leishmaniasis is a vector-borne disease caused by an intracellular protozoan parasite called Leishmania spp. Different species produce different clinical outcomes; the majority of cases are cutaneous forms. major one main causative agents leishmaniasis (CL). Various methods being using to diagnose CL, including microscopic examination, culture, and molecular detection genome.In current study, we tried compare three common markers, Kinetoplast DNA (kDNA), Cytochrome b (Cyt b), Internal...
Abstract Background Leishmaniasis as a neglected tropical disease (NTD) is caused by the inoculation of Leishmania parasites via bite phlebotomine sand flies. After an infected bite, series innate and adaptive immune responses occurs, among which neutrophils can be mentioned initiators. Among multiple functions these fighting cells, neutrophil extracellular traps (NETs) were studied in presence major promastigotes salivary gland homogenates (SGH) Phlebotomus papatasi alone, combination to...
Abstract Background Leishmaniasis as a neglected tropical disease (NTD) is caused by the inoculation of Leishmania parasites via bite phlebotomine sand flies. After an infected bite, series innate and adaptive immune responses occurs, among which neutrophils can be mentioned initiators. Among multiple functions these fighting cells, neutrophil extracellular traps (NETs) were studied in presence major promastigotes salivary gland homogenates (SGH) Phlebotomus papatasi alone, combination to...
Leishmaniasis is a protozoal and vector-borne disease. World health organization has considered the disease as neglected tropical Phlebotomus Lutzumyia species (order: Diptera, family: Psychodidae) are human leishmaniasis vectors in new old worlds. Sergentomyia spp. (Diptera, proven of lizard leishmaniasis. Although some studies have identified Leishmania parasites Sergentomyia, their role parasite circulation unknown yet. Hence, parasitological molecular methods were used to study possible...